Profilin Interaction with Actin Filament Barbed End Controls Dynamic Instability, Capping, Branching, and Motility

por Pernier, Julien, Shekhar, Shashank, Jegou, Antoine, Guichard, Bérengère, Carlier, Marie-France
Publicado 2016

Maternal DNA Methylation Regulates Early Trophoblast Development

por Branco, Miguel R., King, Michelle, Perez-Garcia, Vicente, Bogutz, Aaron B., Caley, Matthew, Fineberg, Elena, Lefebvre, Louis, Cook, Simon J., Dean, Wendy, Hemberger, Myriam, Reik, Wolf
Publicado 2016

T-Cell-Specific Deletion of Map3k1 Reveals the Critical Role for Mekk1 and Jnks in Cdkn1b-Dependent Proliferative Expansion

por Suddason, Tesha, Anwar, Saba, Charlaftis, Nikolaos, Gallagher, Ewen
Publicado 2016

Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion

por Quétier, Ivan, Marshall, Jacqueline J.T., Spencer-Dene, Bradley, Lachmann, Sylvie, Casamassima, Adele, Franco, Claudio, Escuin, Sarah, Worrall, Joseph T., Baskaran, Priththivika, Rajeeve, Vinothini, Howell, Michael, Copp, Andrew J., Stamp, Gordon, Rosewell, Ian, Cutillas, Pedro, Gerhardt, Holger, Parker, Peter J., Cameron, Angus J.M.
Publicado 2016

De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints

por Smock, Robert G., Yadid, Itamar, Dym, Orly, Clarke, Jane, Tawfik, Dan S.
Publicado 2016

Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity

por Dalgaard, Kevin, Landgraf, Kathrin, Heyne, Steffen, Lempradl, Adelheid, Longinotto, John, Gossens, Klaus, Ruf, Marius, Orthofer, Michael, Strogantsev, Ruslan, Selvaraj, Madhan, Lu, Tess Tsai-Hsiu, Casas, Eduard, Teperino, Raffaele, Surani, M. Azim, Zvetkova, Ilona, Rimmington, Debra, Tung, Y.C. Loraine, Lam, Brian, Larder, Rachel, Yeo, Giles S.H., O’Rahilly, Stephen, Vavouri, Tanya, Whitelaw, Emma, Penninger, Josef M., Jenuwein, Thomas, Cheung, Ching-Lung, Ferguson-Smith, Anne C., Coll, Anthony P., Körner, Antje, Pospisilik, J. Andrew
Publicado 2016

IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via Mitochondria at Hippocampal Synapses

por Gazit, Neta, Vertkin, Irena, Shapira, Ilana, Helm, Martin, Slomowitz, Edden, Sheiba, Maayan, Mor, Yael, Rizzoli, Silvio, Slutsky, Inna
Publicado 2016

Excitatory Cerebellar Nucleocortical Circuit Provides Internal Amplification during Associative Conditioning

por Gao, Zhenyu, Proietti-Onori, Martina, Lin, Zhanmin, ten Brinke, Michiel M., Boele, Henk-Jan, Potters, Jan-Willem, Ruigrok, Tom J.H., Hoebeek, Freek E., De Zeeuw, Chris I.
Publicado 2016

A Transient Translaminar GABAergic Interneuron Circuit Connects Thalamocortical Recipient Layers in Neonatal Somatosensory Cortex

por Marques-Smith, Andre, Lyngholm, Daniel, Kaufmann, Anna-Kristin, Stacey, Jacqueline A., Hoerder-Suabedissen, Anna, Becker, Esther B.E., Wilson, Michael C., Molnár, Zoltán, Butt, Simon J.B.
Publicado 2016

Operon Gene Order Is Optimized for Ordered Protein Complex Assembly

por Wells, Jonathan N., Bergendahl, L. Therese, Marsh, Joseph A.
Publicado 2016

L-selectin Is Essential for Delivery of Activated CD8(+) T Cells to Virus-Infected Organs for Protective Immunity

por Mohammed, Rebar N., Watson, H. Angharad, Vigar, Miriam, Ohme, Julia, Thomson, Amanda, Humphreys, Ian R., Ager, Ann
Publicado 2016

Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells

por Macaulay, Iain C., Svensson, Valentine, Labalette, Charlotte, Ferreira, Lauren, Hamey, Fiona, Voet, Thierry, Teichmann, Sarah A., Cvejic, Ana
Publicado 2016

The Gut Epithelial Receptor LRRC19 Promotes the Recruitment of Immune Cells and Gut Inflammation

por Cao, Shuisong, Su, Xiaomin, Zeng, Benhua, Yan, Hui, Huang, Yugang, Wang, Enlin, Yun, Huan, Zhang, Yuan, Liu, Feifei, Li, Wenxia, Wei, Hong, Che, Yongzhe, Yang, Rongcun
Publicado 2016

Structures of the EphA2 Receptor at the Membrane: Role of Lipid Interactions

por Chavent, Matthieu, Seiradake, Elena, Jones, E. Yvonne, Sansom, Mark S.P.
Publicado 2016

Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds

por Zimmer, Jutta, Tacconi, Eliana M.C., Folio, Cecilia, Badie, Sophie, Porru, Manuela, Klare, Kerstin, Tumiati, Manuela, Markkanen, Enni, Halder, Swagata, Ryan, Anderson, Jackson, Stephen P., Ramadan, Kristijan, Kuznetsov, Sergey G., Biroccio, Annamaria, Sale, Julian E., Tarsounas, Madalena
Publicado 2016

Cause and Consequence of Tethering a SubTAD to Different Nuclear Compartments

por Wijchers, Patrick J., Krijger, Peter H.L., Geeven, Geert, Zhu, Yun, Denker, Annette, Verstegen, Marjon J.A.M., Valdes-Quezada, Christian, Vermeulen, Carlo, Janssen, Mark, Teunissen, Hans, Anink-Groenen, Lisette C.M., Verschure, Pernette J., de Laat, Wouter
Publicado 2016

Nonsense-Mediated Decay Restricts LncRNA Levels in Yeast Unless Blocked by Double-Stranded RNA Structure

por Wery, Maxime, Descrimes, Marc, Vogt, Nicolas, Dallongeville, Anne-Sophie, Gautheret, Daniel, Morillon, Antonin
Publicado 2016

Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites

por Wu, Qian, Paul, Atanu, Su, Dan, Mehmood, Shahid, Foo, Tzeh Keong, Ochi, Takashi, Bunting, Emma L., Xia, Bing, Robinson, Carol V., Wang, Bin, Blundell, Tom L.
Publicado 2016

Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination

por Ham, Jungoh, Costa, Carlotta, Sano, Renata, Lochmann, Timothy L., Sennott, Erin M., Patel, Neha U., Dastur, Anahita, Gomez-Caraballo, Maria, Krytska, Kateryna, Hata, Aaron N., Floros, Konstantinos V., Hughes, Mark T., Jakubik, Charles T., Heisey, Daniel A.R., Ferrell, Justin T., Bristol, Molly L., March, Ryan J., Yates, Craig, Hicks, Mark A., Nakajima, Wataru, Gowda, Madhu, Windle, Brad E., Dozmorov, Mikhail G., Garnett, Mathew J., McDermott, Ultan, Harada, Hisashi, Taylor, Shirley M., Morgan, Iain M., Benes, Cyril H., Engelman, Jeffrey A., Mossé, Yael P., Faber, Anthony C.
Publicado 2016

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

por Lechman, Eric R., Gentner, Bernhard, Ng, Stanley W.K., Schoof, Erwin M., van Galen, Peter, Kennedy, James A., Nucera, Silvia, Ciceri, Fabio, Kaufmann, Kerstin B., Takayama, Naoya, Dobson, Stephanie M., Trotman-Grant, Aaron, Krivdova, Gabriela, Elzinga, Janneke, Mitchell, Amanda, Nilsson, Björn, Hermans, Karin G., Eppert, Kolja, Marke, Rene, Isserlin, Ruth, Voisin, Veronique, Bader, Gary D., Zandstra, Peter W., Golub, Todd R., Ebert, Benjamin L., Lu, Jun, Minden, Mark, Wang, Jean C.Y., Naldini, Luigi, Dick, John E.
Publicado 2016