Nfix Regulates Temporal Progression of Muscle Regeneration through Modulation of Myostatin Expression

por Rossi, Giuliana, Antonini, Stefania, Bonfanti, Chiara, Monteverde, Stefania, Vezzali, Chiara, Tajbakhsh, Shahragim, Cossu, Giulio, Messina, Graziella
Publicado 2016

Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy

por Smith, Michael P., Brunton, Holly, Rowling, Emily J., Ferguson, Jennifer, Arozarena, Imanol, Miskolczi, Zsofia, Lee, Jessica L., Girotti, Maria R., Marais, Richard, Levesque, Mitchell P., Dummer, Reinhard, Frederick, Dennie T., Flaherty, Keith T., Cooper, Zachary A., Wargo, Jennifer A., Wellbrock, Claudia
Publicado 2016

Sialic Acid-Binding Immunoglobulin-like Lectin G Promotes Atherosclerosis and Liver Inflammation by Suppressing the Protective Functions of B-1 Cells

por Gruber, Sabrina, Hendrikx, Tim, Tsiantoulas, Dimitrios, Ozsvar-Kozma, Maria, Göderle, Laura, Mallat, Ziad, Witztum, Joseph L., Shiri-Sverdlov, Ronit, Nitschke, Lars, Binder, Christoph J.
Publicado 2016

Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity

por Beerling, Evelyne, Seinstra, Daniëlle, de Wit, Elzo, Kester, Lennart, van der Velden, Daphne, Maynard, Carrie, Schäfer, Ronny, van Diest, Paul, Voest, Emile, van Oudenaarden, Alexander, Vrisekoop, Nienke, van Rheenen, Jacco
Publicado 2016

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

por Campbell, James, Ryan, Colm J., Brough, Rachel, Bajrami, Ilirjana, Pemberton, Helen N., Chong, Irene Y., Costa-Cabral, Sara, Frankum, Jessica, Gulati, Aditi, Holme, Harriet, Miller, Rowan, Postel-Vinay, Sophie, Rafiq, Rumana, Wei, Wenbin, Williamson, Chris T., Quigley, David A., Tym, Joe, Al-Lazikani, Bissan, Fenton, Timothy, Natrajan, Rachael, Strauss, Sandra J., Ashworth, Alan, Lord, Christopher J.
Publicado 2016

A Dynamical Framework for the All-or-None G1/S Transition

por Barr, Alexis R., Heldt, Frank S., Zhang, Tongli, Bakal, Chris, Novák, Béla
Publicado 2016

Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats

por Ori, Alessandro, Toyama, Brandon H., Harris, Michael S., Bock, Thomas, Iskar, Murat, Bork, Peer, Ingolia, Nicholas T., Hetzer, Martin W., Beck, Martin
Publicado 2015

Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches

por Byrne, Kate M., Monsefi, Naser, Dawson, John C., Degasperi, Andrea, Bukowski-Wills, Jimi-Carlo, Volinsky, Natalia, Dobrzyński, Maciej, Birtwistle, Marc R., Tsyganov, Mikhail A., Kiyatkin, Anatoly, Kida, Katarzyna, Finch, Andrew J., Carragher, Neil O., Kolch, Walter, Nguyen, Lan K., von Kriegsheim, Alex, Kholodenko, Boris N.
Publicado 2016

Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA

por Good, James A.D., Andersson, Christopher, Hansen, Sabine, Wall, Jessica, Krishnan, K. Syam, Begum, Afshan, Grundström, Christin, Niemiec, Moritz S., Vaitkevicius, Karolis, Chorell, Erik, Wittung-Stafshede, Pernilla, Sauer, Uwe H., Sauer-Eriksson, A. Elisabeth, Almqvist, Fredrik, Johansson, Jörgen
Publicado 2016

NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions

por Vlantis, Katerina, Wullaert, Andy, Polykratis, Apostolos, Kondylis, Vangelis, Dannappel, Marius, Schwarzer, Robin, Welz, Patrick, Corona, Teresa, Walczak, Henning, Weih, Falk, Klein, Ulf, Kelliher, Michelle, Pasparakis, Manolis
Publicado 2016

A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus Erythematosus

por Menon, Madhvi, Blair, Paul A., Isenberg, David A., Mauri, Claudia
Publicado 2016

Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein

por Behrens, Anna-Janina, Vasiljevic, Snezana, Pritchard, Laura K., Harvey, David J., Andev, Rajinder S., Krumm, Stefanie A., Struwe, Weston B., Cupo, Albert, Kumar, Abhinav, Zitzmann, Nicole, Seabright, Gemma E., Kramer, Holger B., Spencer, Daniel I.R., Royle, Louise, Lee, Jeong Hyun, Klasse, Per J., Burton, Dennis R., Wilson, Ian A., Ward, Andrew B., Sanders, Rogier W., Moore, John P., Doores, Katie J., Crispin, Max
Publicado 2016

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

por Rodriguez, Javier, Pilkington, Ruth, Garcia Munoz, Amaya, Nguyen, Lan K., Rauch, Nora, Kennedy, Susan, Monsefi, Naser, Herrero, Ana, Taylor, Cormac T., von Kriegsheim, Alex
Publicado 2016

The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A

por Segura, Inmaculada, Lange, Christian, Knevels, Ellen, Moskalyuk, Anastasiya, Pulizzi, Rocco, Eelen, Guy, Chaze, Thibault, Tudor, Cicerone, Boulegue, Cyril, Holt, Matthew, Daelemans, Dirk, Matondo, Mariette, Ghesquière, Bart, Giugliano, Michele, Ruiz de Almodovar, Carmen, Dewerchin, Mieke, Carmeliet, Peter
Publicado 2016

Pharmacological Bypass of Cockayne Syndrome B Function in Neuronal Differentiation

por Wang, Yuming, Jones-Tabah, Jace, Chakravarty, Probir, Stewart, Aengus, Muotri, Alysson, Laposa, Rebecca R., Svejstrup, Jesper Q.
Publicado 2016

The SNARE VAMP7 Regulates Exocytic Trafficking of Interleukin-12 in Dendritic Cells

por Chiaruttini, Giulia, Piperno, Giulia M., Jouve, Mabel, De Nardi, Francesca, Larghi, Paola, Peden, Andrew A., Baj, Gabriele, Müller, Sabina, Valitutti, Salvatore, Galli, Thierry, Benvenuti, Federica
Publicado 2016

Neural Progenitors Adopt Specific Identities by Directly Repressing All Alternative Progenitor Transcriptional Programs

por Kutejova, Eva, Sasai, Noriaki, Shah, Ankita, Gouti, Mina, Briscoe, James
Publicado 2016

Memory-Relevant Mushroom Body Output Synapses Are Cholinergic

por Barnstedt, Oliver, Owald, David, Felsenberg, Johannes, Brain, Ruth, Moszynski, John-Paul, Talbot, Clifford B., Perrat, Paola N., Waddell, Scott
Publicado 2016

Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

por Hughes, Michelle A., Powley, Ian R., Jukes-Jones, Rebekah, Horn, Sebastian, Feoktistova, Maria, Fairall, Louise, Schwabe, John W.R., Leverkus, Martin, Cain, Kelvin, MacFarlane, Marion
Publicado 2016

Two Anatomically and Computationally Distinct Learning Signals Predict Changes to Stimulus-Outcome Associations in Hippocampus

por Boorman, Erie D., Rajendran, Vani G., O’Reilly, Jill X., Behrens, Tim E.
Publicado 2016