CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma

por Steele, Colin W., Karim, Saadia A., Leach, Joshua D.G., Bailey, Peter, Upstill-Goddard, Rosanna, Rishi, Loveena, Foth, Mona, Bryson, Sheila, McDaid, Karen, Wilson, Zena, Eberlein, Catherine, Candido, Juliana B., Clarke, Mairi, Nixon, Colin, Connelly, John, Jamieson, Nigel, Carter, C. Ross, Balkwill, Frances, Chang, David K., Evans, T.R. Jeffry, Strathdee, Douglas, Biankin, Andrew V., Nibbs, Robert J.B., Barry, Simon T., Sansom, Owen J., Morton, Jennifer P.
Publicado 2016

Near-Perfect Synaptic Integration by Na(v)1.7 in Hypothalamic Neurons Regulates Body Weight

por Branco, Tiago, Tozer, Adam, Magnus, Christopher J., Sugino, Ken, Tanaka, Shinsuke, Lee, Albert K., Wood, John N., Sternson, Scott M.
Publicado 2016

The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism

por Wootten, Denise, Reynolds, Christopher A., Smith, Kevin J., Mobarec, Juan C., Koole, Cassandra, Savage, Emilia E., Pabreja, Kavita, Simms, John, Sridhar, Rohan, Furness, Sebastian G.B., Liu, Mengjie, Thompson, Philip E., Miller, Laurence J., Christopoulos, Arthur, Sexton, Patrick M.
Publicado 2016

Corpse Engulfment Generates a Molecular Memory that Primes the Macrophage Inflammatory Response

por Weavers, Helen, Evans, Iwan R., Martin, Paul, Wood, Will
Publicado 2016

Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells

por von Meyenn, Ferdinand, Iurlaro, Mario, Habibi, Ehsan, Liu, Ning Qing, Salehzadeh-Yazdi, Ali, Santos, Fátima, Petrini, Edoardo, Milagre, Inês, Yu, Miao, Xie, Zhenqing, Kroeze, Leonie I., Nesterova, Tatyana B., Jansen, Joop H., Xie, Hehuang, He, Chuan, Reik, Wolf, Stunnenberg, Hendrik G.
Publicado 2016

Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination

por Bolland, Daniel J., Koohy, Hashem, Wood, Andrew L., Matheson, Louise S., Krueger, Felix, Stubbington, Michael J.T., Baizan-Edge, Amanda, Chovanec, Peter, Stubbs, Bryony A., Tabbada, Kristina, Andrews, Simon R., Spivakov, Mikhail, Corcoran, Anne E.
Publicado 2016

Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion

por Capellera-Garcia, Sandra, Pulecio, Julian, Dhulipala, Kishori, Siva, Kavitha, Rayon-Estrada, Violeta, Singbrant, Sofie, Sommarin, Mikael N.E., Walkley, Carl R., Soneji, Shamit, Karlsson, Göran, Raya, Ángel, Sankaran, Vijay G., Flygare, Johan
Publicado 2016

CEACAM1-Mediated Inhibition of Virus Production

por Vitenshtein, Alon, Weisblum, Yiska, Hauka, Sebastian, Halenius, Anne, Oiknine-Djian, Esther, Tsukerman, Pinchas, Bauman, Yoav, Bar-On, Yotam, Stern-Ginossar, Noam, Enk, Jonatan, Ortenberg, Rona, Tai, Julie, Markel, Gal, Blumberg, Richard S., Hengel, Hartmut, Jonjic, Stipan, Wolf, Dana G., Adler, Heiko, Kammerer, Robert, Mandelboim, Ofer
Publicado 2016

Robustness of MEK-ERK Dynamics and Origins of Cell-to-Cell Variability in MAPK Signaling

por Filippi, Sarah, Barnes, Chris P., Kirk, Paul D.W., Kudo, Takamasa, Kunida, Katsuyuki, McMahon, Siobhan S., Tsuchiya, Takaho, Wada, Takumi, Kuroda, Shinya, Stumpf, Michael P.H.
Publicado 2016

Translaminar Cortical Membrane Potential Synchrony in Behaving Mice

por Zhao, Wen-Jie, Kremkow, Jens, Poulet, James F.A.
Publicado 2016

Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells

por von Meyenn, Ferdinand, Iurlaro, Mario, Habibi, Ehsan, Liu, Ning Qing, Salehzadeh-Yazdi, Ali, Santos, Fátima, Petrini, Edoardo, Milagre, Inês, Yu, Miao, Xie, Zhenqing, Kroeze, Leonie I., Nesterova, Tatyana B., Jansen, Joop H., Xie, Hehuang, He, Chuan, Reik, Wolf, Stunnenberg, Hendrik G.
Publicado 2016

Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis

por Robson, Michael I., de las Heras, Jose I., Czapiewski, Rafal, Lê Thành, Phú, Booth, Daniel G., Kelly, David A., Webb, Shaun, Kerr, Alastair R.W., Schirmer, Eric C.
Publicado 2016

Cdk1 Phosphorylates Drosophila Sas-4 to Recruit Polo to Daughter Centrioles and Convert Them to Centrosomes

por Novak, Zsofia A., Wainman, Alan, Gartenmann, Lisa, Raff, Jordan W.
Publicado 2016

Protein Abundance Control by Non-coding Antisense Transcription

por Huber, Florian, Bunina, Daria, Gupta, Ishaan, Khmelinskii, Anton, Meurer, Matthias, Theer, Patrick, Steinmetz, Lars M., Knop, Michael
Publicado 2016

T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex

por Hertweck, Arnulf, Evans, Catherine M., Eskandarpour, Malihe, Lau, Jonathan C.H., Oleinika, Kristine, Jackson, Ian, Kelly, Audrey, Ambrose, John, Adamson, Peter, Cousins, David J., Lavender, Paul, Calder, Virginia L., Lord, Graham M., Jenner, Richard G.
Publicado 2016

SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis

por Elkouris, Maximilianos, Kontaki, Haroula, Stavropoulos, Athanasios, Antonoglou, Anastasia, Nikolaou, Kostas C., Samiotaki, Martina, Szantai, Eszter, Saviolaki, Dimitra, Brown, Peter J., Sideras, Paschalis, Panayotou, George, Talianidis, Iannis
Publicado 2016

Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth

por Rowald, Konstantina, Mantovan, Martina, Passos, Joana, Buccitelli, Christopher, Mardin, Balca R., Korbel, Jan O., Jechlinger, Martin, Sotillo, Rocio
Publicado 2016

Risk Taking for Potential Reward Decreases across the Lifespan

por Rutledge, Robb B., Smittenaar, Peter, Zeidman, Peter, Brown, Harriet R., Adams, Rick A., Lindenberger, Ulman, Dayan, Peter, Dolan, Raymond J.
Publicado 2016

Unique Cellular Organization in the Oldest Root Meristem

por Hetherington, Alexander J., Dubrovsky, Joseph G., Dolan, Liam
Publicado 2016

Diversification of a Transcription Factor Family Led to the Evolution of Antagonistically Acting Genetic Regulators of Root Hair Growth

por Breuninger, Holger, Thamm, Anna, Streubel, Susanna, Sakayama, Hidetoshi, Nishiyama, Tomoaki, Dolan, Liam
Publicado 2016