Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues

por Davies, Katherine A., Fitzgibbon, Cheree, Young, Samuel N., Garnish, Sarah E., Yeung, Wayland, Coursier, Diane, Birkinshaw, Richard W., Sandow, Jarrod J., Lehmann, Wil I. L., Liang, Lung-Yu, Lucet, Isabelle S., Chalmers, James D., Patrick, Wayne M., Kannan, Natarajan, Petrie, Emma J., Czabotar, Peter E., Murphy, James M.
Publicado 2020

Low-Dose vs Standard-Dose Alteplase in Acute Lacunar Ischemic Stroke: The ENCHANTED Trial

por Zhou, Zien, Delcourt, Candice, Xia, Chao, Yoshimura, Sohei, Carcel, Cheryl, Torii-Yoshimura, Takako, You, Shoujiang, Malavera, Alejandra, Chen, Xiaoying, Hackett, Maree L., Woodward, Mark, Chalmers, John, Xu, Jianrong, Robinson, Thompson G., Parsons, Mark W., Demchuk, Andrew M., Lindley, Richard I., Mair, Grant, Wardlaw, Joanna M., Anderson, Craig S.
Publicado 2021

Recommended core outcome instruments for health‐related quality of life, long‐term control and itch intensity in atopic eczema trials: results of the HOME VII consensus meeting

por Thomas, K.S., Apfelbacher, C.A., Chalmers, J.R., Simpson, E., Spuls, P.I., Gerbens, L.A.A., Williams, H.C., Schmitt, J., Gabes, M., Howells, L., Stuart, B.L., Grinich, E., Pawlitschek, T., Burton, T., Howie, L., Gadkari, A., Eckert, L., Ebata, T., Boers, M., Saeki, H., Nakahara, T., Katoh, N.
Publicado 2021

The CD6/ALCAM pathway promotes lupus nephritis via T cell–mediated responses

por Chalmers, Samantha A., Ayilam Ramachandran, Rajalakshmy, Garcia, Sayra J., Der, Evan, Herlitz, Leal, Ampudia, Jeanette, Chu, Dalena, Jordan, Nicole, Zhang, Ting, Parodis, Ioannis, Gunnarsson, Iva, Ding, Huihua, Shen, Nan, Petri, Michelle, Mok, Chi Chiu, Saxena, Ramesh, Polu, Krishna R., Connelly, Stephen, Ng, Cherie T., Mohan, Chandra, Putterman, Chaim
Publicado 2022

Cardiovascular Safety in Type 2 Diabetes With Sulfonylureas as Second-line Drugs: A Nationwide Population-Based Comparative Safety Study

por Wang, Huan, Cordiner, Ruth L.M., Huang, Yu, Donnelly, Louise, Hapca, Simona, Collier, Andrew, McKnight, John, Kennon, Brian, Gibb, Fraser, McKeigue, Paul, Wild, Sarah H., Colhoun, Helen, Chalmers, John, Petrie, John, Sattar, Naveed, MacDonald, Thomas, McCrimmon, Rory J., Morales, Daniel R., Pearson, Ewan R.
Publicado 2023

Glutamine Synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

por Tardito, Saverio, Oudin, Anaïs, Ahmed, Shafiq U., Fack, Fred, Keunen, Olivier, Zheng, Liang, Miletic, Hrvoje, Sakariassen, Per Øystein, Weinstock, Adam, Wagner, Allon, Lindsay, Susan L., Hock, Andreas K., Barnett, Susan C., Ruppin, Eytan, Mørkve, Svein Harald, Lund-Johansen, Morten, Chalmers, Anthony J., Bjerkvig, Rolf, Niclou, Simone P., Gottlieb, Eyal
Publicado 2015

A clinical-scale BioArtificial Liver, developed for GMP, improved clinical parameters of liver function in porcine liver failure

por Selden, Clare, Bundy, James, Erro, Eloy, Puschmann, Eva, Miller, Malcolm, Kahn, Delawir, Hodgson, Humphrey, Fuller, Barry, Gonzalez-Molina, Jordi, Le Lay, Aurelie, Gibbons, Stephanie, Chalmers, Sherri, Modi, Sunil, Thomas, Amy, Kilbride, Peter, Isaacs, Agnes, Ginsburg, Richard, Ilsley, Helen, Thomson, David, Chinnery, Galya, Mankahla, Ncedile, Loo, Lizel, Spearman, C. Wendy
Publicado 2017

Genetic Diversity of Cryptosporidium hominis in a Bangladeshi Community as Revealed by Whole-Genome Sequencing

por Gilchrist, Carol A, Cotton, James A, Burkey, Cecelia, Arju, Tuhinur, Gilmartin, Allissia, Lin, Ye, Ahmed, Emtiaz, Steiner, Kevin, Alam, Masud, Ahmed, Shahnawaz, Robinson, Guy, Zaman, Sultan Uz, Kabir, Mamun, Sanders, Mandy, Chalmers, Rachel M, Ahmed, Tahmeed, Ma, Jennie Z, Haque, Rashidul, Faruque, Abu S G, Berriman, Matthew, Petri, William A
Publicado 2018

Clinical and research priorities for children and young people with bronchiectasis: an international roadmap

por Chang, Anne B., Boyd, Jeanette, Bell, Leanne, Goyal, Vikas, Masters, I. Brent, Powell, Zena, Wilson, Christine, Zacharasiewicz, Angela, Alexopoulou, Efthymia, Bush, Andrew, Chalmers, James D., Fortescue, Rebecca, Hill, Adam T., Karadag, Bulent, Midulla, Fabio, McCallum, Gabrielle B., Snijders, Deborah, Song, Woo-Jung, Tonia, Thomy, Grimwood, Keith, Kantar, Ahmad
Publicado 2021

LTA4H rs2660845 association with montelukast response in early and late-onset asthma

por Maroteau, Cyrielle, Espuela-Ortiz, Antonio, Herrera-Luis, Esther, Srinivasan, Sundararajan, Carr, Fiona, Tavendale, Roger, Wilson, Karen, Hernandez-Pacheco, Natalia, Chalmers, James D., Turner, Steve, Mukhopadhyay, Somnath, Maitland-van der Zee, Anke-Hilse, Burchard, Esteban G., Pino-Yanes, Maria, Young, Simon, Lassi, Glenda, Platt, Adam, Palmer, Colin N. A.
Publicado 2021

Statistical reanalysis of vascular event outcomes in primary and secondary vascular prevention trials

por Woodhouse, Lisa J., Montgomery, Alan A., Mant, Jonathan, Davis, Barry R., Algra, Ale, Mas, Jean-Louis, Staessen, Jan A., Thijs, Lutgarde, Tonkin, Andrew, Kirby, Adrienne, Pocock, Stuart J., Chalmers, John, Hankey, Graeme J., Spence, J. David, Sandercock, Peter, Diener, Hans-Christoph, Uchiyama, Shinichiro, Sprigg, Nikola, Bath, Philip M.
Publicado 2021

Diel activity patterns of two distinct populations of Aedes aegypti in Miami, FL and Brownsville, TX

por Mutebi, John-Paul, Wilke, André Barretto Bruno, Ostrum, Erik, Vasquez, Chalmers, Cardenas, Gabriel, Carvajal, Augusto, Moreno, Maday, Petrie, William D., Rodriguez, Arturo, Presas, Henry, Rodriguez, Jesus, Barnes, Fred, Hamer, Gabriel L., Juarez, Jose G., Carbajal, Ester, Vitek, Christopher J., Estrada, Xochitl, Rios, Thalia, Marshall, Jeremy, Beier, John C.
Publicado 2022

The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor–resistant ER(+) breast cancer with mitotic aberrations

por Soria-Bretones, Isabel, Thu, Kelsie L., Silvester, Jennifer, Cruickshank, Jennifer, El Ghamrasni, Samah, Ba-alawi, Wail, Fletcher, Graham C., Kiarash, Reza, Elliott, Mitchell J., Chalmers, Jordan J., Elia, Andrea C., Cheng, Albert, Rose, April A. N., Bray, Mark R., Haibe-Kains, Benjamin, Mak, Tak W., Cescon, David W.
Publicado 2022

Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis

por Nazarzadeh, Milad, Bidel, Zeinab, Canoy, Dexter, Copland, Emma, Bennett, Derrick A, Dehghan, Abbas, Davey Smith, George, Holman, Rury R, Woodward, Mark, Gupta, Ajay, Adler, Amanda I, Wamil, Malgorzata, Sattar, Naveed, Cushman, William C, McManus, Richard J, Teo, Koon, Davis, Barry R, Chalmers, John, Pepine, Carl J, Rahimi, Kazem
Publicado 2022

CinE caRdiac magneTic resonAnce to predIct veNTricular arrhYthmia (CERTAINTY)

por Krebs, Julian, Mansi, Tommaso, Delingette, Hervé, Lou, Bin, Lima, Joao A. C., Tao, Susumu, Ciuffo, Luisa A., Norgard, Sanaz, Butcher, Barbara, Lee, Wei H., Chamera, Ela, Dickfeld, Timm-Michael, Stillabower, Michael, Marine, Joseph E., Weiss, Robert G., Tomaselli, Gordon F., Halperin, Henry, Wu, Katherine C., Ashikaga, Hiroshi
Publicado 2021

Anti-Diabetic Actions of a Non-Agonist PPARγ Ligand Blocking Cdk5-Mediated Phosphorylation

por Choi, Jang Hyun, Banks, Alexander S., Kamenecka, Theodore M., Busby, Scott A., Chalmers, Michael J., Kumar, Naresh, Kuruvilla, Dana S., Shin, Youseung, He, Yuanjun, Bruning, John B., Marciano, David P., Cameron, Michael D., Laznik, Dina, Jurczak, Michael J., Schürer, Stephan C., Vidović, Dušica, Shulman, Gerald I., Spiegelman, Bruce M., Griffin, Patrick R.
Publicado 2011

STUMP un“stumped”: anti-tumor response to anaplastic lymphoma kinase (ALK) inhibitor based targeted therapy in uterine inflammatory myofibroblastic tumor with myxoid features harbo...

por Subbiah, Vivek, McMahon, Caitlin, Patel, Shreyaskumar, Zinner, Ralph, Silva, Elvio G, Elvin, Julia A., Subbiah, Ishwaria M., Ohaji, Chimela, Ganeshan, Dhakshina Moorthy, Anand, Deepa, Levenback, Charles F., Berry, Jenny, Brennan, Tim, Chmielecki, Juliann, Chalmers, Zachary R., Mayfield, John, Miller, Vincent A., Stephens, Philip J., Ross, Jeffrey S., Ali, Siraj M.
Publicado 2015

Including all voices in international data-sharing governance

por Kaye, Jane, Terry, Sharon F., Juengst, Eric, Coy, Sarah, Harris, Jennifer R., Chalmers, Don, Dove, Edward S., Budin-Ljøsne, Isabelle, Adebamowo, Clement, Ogbe, Emilomo, Bezuidenhout, Louise, Morrison, Michael, Minion, Joel T., Murtagh, Madeleine J., Minari, Jusaku, Teare, Harriet, Isasi, Rosario, Kato, Kazuto, Rial-Sebbag, Emmanuelle, Marshall, Patricia, Koenig, Barbara, Cambon-Thomsen, Anne
Publicado 2018

A 2 × 2 factorial, randomised, open-label trial to determine the clinical and cost-effectiveness of hypertonic saline (HTS 6%) and carbocisteine for airway clearance versus usual c...

por Bradley, Judy Martina, Anand, Rohan, O’Neill, Brenda, Ferguson, Kathryn, Clarke, Mike, Carroll, Mary, Chalmers, James, De Soyza, Anthony, Duckers, Jamie, Hill, Adam T., Loebinger, Michael R., Copeland, Fiona, Gardner, Evie, Campbell, Christina, Agus, Ashley, McGuire, Alistair, Boyle, Roisin, McKinney, Fionnuala, Dickson, Naomi, McAuley, Danny F., Elborn, Stuart
Publicado 2019

Multiple breath washout in bronchiectasis clinical trials: is it feasible?

por O'Neill, Katherine, Ferguson, Kathryn, Cosgrove, Denis, Tunney, Michael M., De Soyza, Anthony, Carroll, Mary, Chalmers, James D., Gatheral, Timothy, Hill, Adam T., Hurst, John R., Johnson, Christopher, Loebinger, Michael R., Angyalosi, Gerhild, Haworth, Charles S., Jensen, Renee, Ratjen, Felix, Saunders, Clare, Short, Christopher, Davies, Jane C., Elborn, J. Stuart, Bradley, Judy M.
Publicado 2020