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2121“…We believe that the results of our 2% EDTA chelation treatment were comparable with results obtained with 3.75% EDTA chelation treatment in previous reports. …”
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2122por Sung, Kyung-Il, Ghassemi Nejad, Jalil, Hong, Seok-Man, Ohh, Sang-Jip, Lee, Bae-Hun, Peng, Jing-Lun, Ji, Do-Hyeon, Kim, Byong-Wan“…It is concluded that supplementation of chromium-methionine chelate could improve meat quality in beef steers.…”
Publicado 2015
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2123por Pinto, Valeria, Balocco, Manuela, Ambaglio, Ilaria, Derchi, Giorgio, Malcovati, Luca, Forni, Gian Luca“…Here, we report the recovery of cardiac function after an intensive iron chelation therapy in a MDS patient who had developed heart failure due to iron overload.…”
Publicado 2015
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2124por Senol, Sefika Pinar, Tiftik, Eyup Naci, Unal, Selma, Akdeniz, Aydan, Tasdelen, Bahar, Tunctan, Bahar“…OBJECTIVES: There is a need to remove excess iron with iron chelation therapy (ICT) to avoid the serious clinical sequelae associated with iron overload in patients with beta thalassemia major (BTM) and sickle cell anemia (SCA). …”
Publicado 2016
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2125por Lee, Jehn-Chuan, Chiang, Kun-Chun, Feng, Tsui-Hsia, Chen, Yu-Jen, Chuang, Sung-Ting, Tsui, Ke-Hung, Chung, Li-Chuan, Juang, Horng-Heng“…Current research has considered iron chelators as new anti-cancer agents; however, the anticancer activities of iron chelators and their target genes in OSCC have not been well investigated. …”
Publicado 2016
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2126por Zwanenburg, Renée J, Bocca, Gianni, Ruiter, Selma A J, Dillingh, Jan H, Flapper, Boudien C T, van den Heuvel, Edwin R, van Ravenswaaij-Arts, Conny M A“…Phelan-McDermid syndrome (PMS) or 22q13.3 deletion syndrome is a rare neurodevelopmental disorder with at least 60 children and 35 adults diagnosed in the Netherlands. …”
Publicado 2016
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2127
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2128“…Erythrocytapheresis can limit iron loading and oral chelation provides a more tolerable alternative to subcutaneous administration. …”
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2129por Taher, Ali T, Porter, John B, Kattamis, Antonis, Viprakasit, Vip, Cappellini, M DomenicaEnlace del recurso
Publicado 2016
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2130“…Phelan McDermid Syndrome (PHMDS) (OMIM #606232), is a contiguous gene disorder resulting from deletion of the distal long arm of chromosome 22. …”
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2131por Hierlinger, Claus, Roisnel, Thierry, Cordes, David B., Slawin, Alexandra M. Z., Jacquemin, Denis, Guerchais, Véronique, Zysman-Colman, Eli“…[Image: see text] A new family consisting of three luminescent neutral Ir(III) complexes with the unprecedented [Ir(C^N^C)(N^N)Cl] architecture, where C^N^C is a bis(six-membered) chelating tridentate tripod ligand derived from 2-benzhydrylpyridine (bnpy) and N^N is 4,4′-di-tert-butyl-2,2′-bipyridine (dtBubpy), is reported. …”
Publicado 2017
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2132por Martin-Bastida, Antonio, Ward, Roberta J., Newbould, Rexford, Piccini, Paola, Sharp, David, Kabba, Christina, Patel, Maneesh C., Spino, Michael, Connelly, John, Tricta, Fernando, Crichton, Robert R., Dexter, David T.“…This study evaluated whether the iron chelator, deferiprone, is well tolerated, able to chelate iron from various brain regions and improve PD symptomology. …”
Publicado 2017
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2133por Maximova, Natalia, Gregori, Massimo, Simeone, Roberto, Sonzogni, Aurelio, Boz, Giulia, Fucile, Carmen, Marini, Valeria, Martelli, Antonietta, Mattioli, Francesca“…In the DFX C(trough) < 10 mcg/mL group only one patient interrupted chelation therapy versus 16 (84.2%) patients in the DFX C(trough) > 10 mcg/mL group. …”
Publicado 2017
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2134“…Biological chelating molecules called siderophores are used to sequester iron and maintain its ferric state. …”
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2135“…Recent proteomic studies have identified that Ferric Chelate Reductase 1 Like protein (FRRS1L), whose mutations in human lead to epilepsy, choreoathetosis, and cognitive deficits, is present in native AMPAR complexes in the brain. …”
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2136“…BACKGROUND: We recently developed a chelating platform based on the macrocycle 1,4,7-triazacyclononane with up to three, five-membered azaheterocyclic arms for the development of (68)Ga- and (64)Cu-based radiopharmaceuticals. …”
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2137por Leblanc, Nicolas, Sproules, Stephen, Fink, Karin, Sanguinet, Lionel, Alévêque, Olivier, Levillain, Eric, Rosa, Patrick, Powell, Annie K.“…To intimately combine a chelating ligand function with the numerous properties of a viologen-like redox-active centre would offer a rare possibility to design controllable multi-redox states, whose properties arise from strongly correlated phenomena between the organic ligand as well as with any metalloid coordinated centres. …”
Publicado 2016
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2138por Oroujeni, Maryam, Andersson, Ken G., Steinhardt, Xenia, Altai, Mohamed, Orlova, Anna, Mitran, Bogdan, Vorobyeva, Anzhelika, Garousi, Javad, Tolmachev, Vladimir, Löfblom, John“…The (99m)Tc-labeled variant containing the EEEC chelator provided the highest tumor-to-organ ratios. …”
Publicado 2018
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2139por Sengupta, Sagnik, Krishnan, Mena Asha, Dudhe, Premansh, Reddy, Ramesh B, Giri, Bishnubasu, Chattopadhyay, Sudeshna, Chelvam, Venkatesh“…In this article, we have successfully designed and demonstrated a novel continuous process for assembling targeting ligands, peptidic spacers, fluorescent tags and a chelating core for the attachment of cytotoxic molecules, radiotracers, nanomaterials in a standard Fmoc solid-phase peptide synthesis in high yield and purity. …”
Publicado 2018
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2140por Máté, Gábor, Šimeček, Jakub, Pniok, Miroslav, Kertész, István, Notni, Johannes, Wester, Hans-Jürgen, Galuska, László, Hermann, Petr“…Overall, replacement of a single phosphinate donor with a carboxylate does not challenge (68)Ga labelling of TRAP-type chelators. However, the presence of carboxylates facilitates labelling at neutral or weakly acidic pH.…”
Publicado 2015
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