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  1. 2161
    “…Here, we investigated the use of a bacterial strain as a living iron chelator, competing for this nutrient vital to tumor growth and progression. …”
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    Magnetospirillum magneticum as a Living Iron Chelator Induces TfR1 Upregulation and Decreases Cell Viability in Cancer Cells
  2. 2162
    “…The aim of our research was to find a universal chelator that enables the attachment of sensitive bio(macro)molecules and allows (225)Ac-radiolabeling under mild conditions. …”
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    Towards Targeted Alpha Therapy with Actinium-225: Chelators for Mild Condition Radiolabeling and Targeting PSMA—A Proof of Concept Study
  3. 2163
    “…Since the enzymatic characteristics of the ferric chelate reductase (FCR) activity of purified chloroplast inner envelope membranes showed a significant loss for the substrate affinity with an unchanged saturation rate, protein level regulation mechanisms are suggested to be also involved in the suppression of the reduction-based Fe uptake of chloroplasts together with the saturation of the requirement for Fe.…”
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    Supraoptimal Iron Nutrition of Brassica napus Plants Suppresses the Iron Uptake of Chloroplasts by Down-Regulating Chloroplast Ferric Chelate Reductase
  4. 2164
    “…The bio-based lactic acid (LA) and the common metal ion chelating agent iminodiacetic acid (IDA) are used to design and prepare a polymeric sustained-release Pb(2+) chelating agent by a brief one-step reaction. …”
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    Controllable preparation and performance of bio-based poly(lactic acid-iminodiacetic acid) as sustained-release Pb(2+) chelating agent
  5. 2165
    “…Phelan‐McDermid syndrome (PMS, OMIM #606232), also known as chromosome 22q13 deletion syndrome, is a rare genetic disorder characterized by intellectual disability, hypotonia, delayed or absent speech, motor impairment, autism spectrum disorder, behavioral anomalies, and minor aspecific dysmorphic features. …”
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    Genotype–phenotype correlation in Phelan‐McDermid syndrome: A comprehensive review of chromosome 22q13 deleted genes
  6. 2166
    “…CONCLUSION: This study shows for the first time that local/immediate application of Ca++ chelator BAPTA is strongly neuroprotective after severe spinal cord injury.…”
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    BAPTA, a calcium chelator, neuroprotects injured neurons in vitro and promotes motor recovery after spinal cord transection in vivo
  7. 2167
    “…Thus, the combined application of 1.5% Zn-lysine chelates along with ZSB inoculation could be used for combating malnutrition.…”
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    Combined application of zinc-lysine chelate and zinc-solubilizing bacteria improves yield and grain biofortification of maize (Zea mays L.)
  8. 2168
    “…Adjustment of iron chelation therapy did not improve visual function. …”
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    Iron overload and iron chelating agent exposure in anemia-associated outer retinal degeneration: a case report and review of the literature
  9. 2169
    “…SIMPLE SUMMARY: The thick-lipped grey mullet (Chelon labrosus) has good potential for aquaculture diversification in Europe. …”
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    Cultivated and Wild Juvenile Thick-Lipped Grey Mullet, Chelon labrosus: A Comparison from a Nutritional Point of View
  10. 2170
    “…A combination of inorganic and chelated Zn and Mn may improve performance and increase total breast meat yields.…”
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    Effect of methionine chelated Zn and Mn and corn particle size on Large White male turkey live performance and carcass yields
  11. 2171
    “…The study aimed to explore the application value of lumbar Magnetic Resonance Imaging (MRI) images processed by artificial intelligence algorithms in evaluating the efficacy of chinkuei shin chewan decoction (a traditional Chinese medicine to nourish the kidney) in the treatment of lumbar spinal stenosis (LSS). …”
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    Artificial Intelligence Algorithm-Based Lumbar and Spinal MRI for Evaluation of Efficacy of Chinkuei Shin Chewan Decoction on Lumbar Spinal Stenosis
  12. 2172
    “…Two tetradentate dibasic chelating Schiff base iron (III) chelates were prepared from the reaction of 2,2′-((1E,1′E)-(1,2-phenylenebis(azanylylidene))bis(methanylylidene))bis(4-bromophenol) (PDBS) and 2,2′-((1E,1′E)-((4-chloro-1,2-phenylene)bis(azanylylidene))-bis(methanylylidene))bis(4-bromophenol) (CPBS) with Fe(3+) ions. …”
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    Fabrication, DFT Calculation, and Molecular Docking of Two Fe(III) Imine Chelates as Anti-COVID-19 and Pharmaceutical Drug Candidate
  13. 2173
    “…The calcium–chelating capacity was 42.57 ± 0.09%. The results of ultraviolet absorption spectrum, Fourier transform infrared (FT-IR) spectra, differential scanning calorimeter (DSC), X-ray diffraction and amino acid analysis indicated that calcium could be chelated through carboxyl oxygen and amino nitrogen atoms of collagen peptides, forming peptide–calcium chelate. …”
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    Preparation of sheep bone collagen peptide–calcium chelate using enzymolysis-fermentation methodology and its structural characterization and stability analysis
  14. 2174
    “…Two visits 13 months apart included clinical assessment and chelation therapy recommendations based on rapid CMR results. …”
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    Use of rapid cardiac magnetic resonance imaging to guide chelation therapy in patients with transfusion-dependent thalassaemia in India: UMIMI study
  15. 2175
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    One pot synthesis of two cobalt(iii) Schiff base complexes with chelating pyridyltetrazolate and exploration of their bio-relevant catalytic activities
  16. 2176
    “…BACKGROUND: Although iron chelation has garnered attention as a novel therapeutic strategy for cancer, higher levels of efficacy need to be achieved. …”
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    An iron chelation-based combinatorial anticancer therapy comprising deferoxamine and a lactate excretion inhibitor inhibits the proliferation of cancer cells
  17. 2177
    “…Reaction of compounds 3 with CO and CNtBu afforded the opening of the Ru(κ(2)-pyO) chelate motif with the formation of compounds [PhP(μ-pic)(2)(μ-pyO)Ru(κ-O-pyO)(CO)] (4a), [PhP(μ-pic)(2)(μ-pyO)(2)Ru(CNtBu)] (5a), [PhP(μ-pyO)(4)Ru(CO)] (4b) and [PhP(μ-pyO)(4)Ru(CNtBu)] (5b). …”
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    P–Ru-Complexes with a Chelate-Bridge-Switch: A Comparison of 2-Picolyl and 2-Pyridyloxy Moieties as Bridging Ligands
  18. 2178
    “…We therefore hypothesized copper chelation may represent an effective therapeutic strategy for DIPG. …”
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    DIPG-20. Copper chelation therapy targets S-adenosylmethionine (SAM) metabolism and epigenetic regulators in diffuse intrinsic pontine glioma (DIPG)
  19. 2179
    “…When radiometals are employed in nuclear imaging, a chelator is typically inserted into the molecule to facilitate radiolabeling; the availability of the chelator further expands the potential use of these platforms for targeted radionuclide therapy if a therapeutic radiometal is employed. …”
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    Development of a multi faceted platform containing a tetrazine, fluorophore and chelator: synthesis, characterization, radiolabeling, and immuno-SPECT imaging
  20. 2180
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    Casiopeinas of Third Generations: Synthesis, Characterization, Cytotoxic Activity and Structure–Activity Relationships of Mixed Chelate Compounds with Bioactive Secondary Ligands
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