“…Starting from hydrazine, we described an approach to create new dendritic pseudopeptides linked with biological systems, such as cell membrane, as chelate metal, Ni(2+)-nitrilotriacetic acid moieties which could target histidine rich peptides or proteins. …”
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“…In the present study, we utilized two zinc chelators, N,N,N′,N′-tetrakis (2-pyridylmethyl) ethane-1,2-diamine (TPEN) and 2,3-dimercapto-1-propanesulfonic acid (DMPS) to explore the effect of zinc limitation on aflatoxin synthesis in Aspergillus parasiticus. …”
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“…ChemProteoBase profiling showed that CMA is closely clustered with di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone, an iron chelator. CMA bound to both Fe(II) and Fe(III) ions and formed a 2:1 chelator-iron complex with a redox-inactive center. …”
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“…The development of bifunctional chelators (BFCs) for zirconium-89 immuno-PET applications is an area of active research. …”
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“…Our findings show the proof of principle of chelator scaffolding for hybrid imaging agents and demonstrate FSC being a suitable bifunctional chelator for this approach. …”
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“…In this study, the antioxidant activity of the iron chelators: caffeic acid (CA), 2,3-dihydroxybenzoic acid (DHBA), desferroxamine B (FOB) and benzohydroxamic acid (BHA) were determined using five different in vitro antioxidant assays. …”
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“…Gallium-68 ((68)Ga) is a positron-emitting isotope used for clinical PET imaging of peptide receptor expression. (68)Ga radiopharmaceuticals used in molecular PET imaging consist of disease-targeting biomolecules tethered to chelators that complex (68)Ga(3+). Ideally, the chelator will rapidly, quantitatively and stably coordinate (68)Ga(3+) at room temperature, near neutral pH and low chelator concentration, allowing for simple routine radiopharmaceutical formulation. …”
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“…AIM: This study aimed to compare, through dentin microhardness and colorimetric analysis, the chelating effect of 0.2% chitosan solubilized in different acids. …”
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“…Moreover, most of the investigated hydroxamic acids were stronger Fe(2+) ion chelators than quercetin. In addition, the investigated compounds, especially hydroxamic acids, were proven to be excellent antioxidants. …”
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“…A new class of multifunctionalized sarcophagine derivatives was synthesized for (64)Cu chelation. The platform developed in this study could have broad applications in (64)Cu-radiopharmaceuticals.…”
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“…Zinc chelate of methionine sulfate is intended to be used as a nutritional additive (functional group: compounds of trace elements). …”
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“…Each subject underwent a chelation test with the chelating agent calcium disodium ethylenediaminetetraacetic acid (CaNA(2)EDTA or EDTA) to identify the presence of 20 toxic metals in urine samples using inductively coupled plasma mass spectrometry. …”
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“…Furthermore, patients with progressive or relapsed disease had higher SF levels. Importantly, iron chelation with DFO efficiently inhibited myeloma cell survival and accelerated apoptosis by regulating apoptosis-related genes. …”
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“…In this narrative review, we examine the latest data on the use of oral nonspecific and specific intestinal chelators to reduce levels of gut-derived uremic toxins.…”
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“…The nicotianamine-iron chelate [NA-Fe(2+)], which is found in many plant-based foods, has been recently described as a new form of bioavailable iron in mice and chickens. …”
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“…Iron loading in some brain regions occurs in Parkinson’s Disease (PD), and it has been considered that its removal by iron chelators could be an appropriate therapeutic approach. …”
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