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  1. 2401
    “…In our current investigation, we evaluated the effect of Chlorella pyrenoidosa protein hydrolysate (CPPH) and Chlorella pyrenoidosa protein hydrolysate-calcium chelate (CPPH-Ca) on calcium absorption and gut microbiota composition, as well as their in vivo regulatory mechanism in SD rats fed low-calcium diets. …”
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    Effect of Chlorella Pyrenoidosa Protein Hydrolysate-Calcium Chelate on Calcium Absorption Metabolism and Gut Microbiota Composition in Low-Calcium Diet-Fed Rats
  2. 2402
    por Tosato, Marianna, Di Marco, Valerio
    Publicado 2019
    “…Among these compounds, approximately 250 have possible or established metal-chelating properties towards Cu(II), Cu(I), Fe(III), Fe(II), Mn(II), and Zn(II), which are considered to be involved in metal dyshomeostasis during PD. …”
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    Metal Chelation Therapy and Parkinson’s Disease: A Critical Review on the Thermodynamics of Complex Formation between Relevant Metal Ions and Promising or Established Drugs
  3. 2403
    “…Time-of-addition experiments suggested that zinc chelation affected both early and late stages of dengue virus infectious cycle and zinc chelation abrogated dengue virus RNA replication. …”
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    Zinc Chelation Specifically Inhibits Early Stages of Dengue Virus Replication by Activation of NF-κB and Induction of Antiviral Response in Epithelial Cells
  4. 2404
    “…Siderophores are iron chelators with low molecular weight secreted by microorganisms. …”
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    Siderophore (from Synechococcus sp. PCC 7002)-Chelated Iron Promotes Iron Uptake in Caco-2 Cells and Ameliorates Iron Deficiency in Rats
  5. 2405
    “…The tailor‐made adsorbent, Cu(I)@UiO‐66‐(COOH)(2), thus possesses the optimal pore window size and chelated Cu(I) ions to form π‐complexation with C(2)H(4) molecules. …”
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    Boosting Ethylene/Ethane Separation within Copper(I)‐Chelated Metal–Organic Frameworks through Tailor‐Made Aperture and Specific π‐Complexation
  6. 2406
    “…In conclusion, EGCG possesses iron chelator property in CRC and this potential could be further exploited for CRC treatment.…”
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    Iron Chelation Properties of Green Tea Epigallocatechin-3-Gallate (EGCG) in Colorectal Cancer Cells: Analysis on Tfr/Fth Regulations and Molecular Docking
  7. 2407
    “…This inhibitor has been adopted recently by other groups to create radiopharmaceuticals by coupling bifunctional chelator-linker systems. Here, we report squaric acid (SA) containing bifunctional DATA(5m) and DOTA chelators based on UAMC1110 as pharmacophor. …”
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    Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA(5m) chelators
  8. 2408
    “…Accordingly, the oral iron chelator Deferasirox (DFX) has been reported to improve the OS and delay leukemic transformation. …”
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    Deferasirox-Dependent Iron Chelation Enhances Mitochondrial Dysfunction and Restores p53 Signaling by Stabilization of p53 Family Members in Leukemic Cells
  9. 2409
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    Design and Synthesis of a Dual-Purpose Superadsorbent Containing a High Density of Chelating Motifs for the Fast Mitigation of Methylene Blue and Pb(II)
  10. 2410
    por Oh-e, Masahito, Nagasawa, Akira
    Publicado 2020
    “…Therefore, DGA enables efficient quenching through the chelate effect when it binds to Ce(3+).…”
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    Interactions Between Hydrated Cerium(III) Cations and Carboxylates in an Aqueous Solution: Anomalously Strong Complex Formation with Diglycolate, Suggesting a Chelate Effect
  11. 2411
    “…Here, we optimized site-specific conjugation of both a chelator for binding of a radiometal and a photosensitizer to epidermal growth factor receptor (EGFR) binding VHH 7D12. …”
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    Site-Specific Dual-Labeling of a VHH with a Chelator and a Photosensitizer for Nuclear Imaging and Targeted Photodynamic Therapy of EGFR-Positive Tumors
  12. 2412
    por Zamai, Loris
    Publicado 2021
    “…The article describes the rationale for the administration of zinc-chelating agents in COVID-19 patients. In a previous work I have highlighted that the binding of the SARS-CoV spike proteins to the zinc-metalloprotease ACE2 has been shown to induce ACE2 shedding by activating the zinc-metalloprotease ADAM17, which ultimately leads to systemic upregulation of ACE2 activity. …”
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    Upregulation of the Renin–Angiotensin System Pathways and SARS-CoV-2 Infection: The Rationale for the Administration of Zinc-Chelating Agents in COVID-19 Patients
  13. 2413
    “…Associated adjuvant iron chelators may contribute to a good outcome and needs to be confirmed in larger studies.…”
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    Off-label tocilizumab and adjuvant iron chelator effectiveness in a group of severe COVID-19 pneumonia patients: A single center experience
  14. 2414
    “…The exergonicity of chelation reactions of the catalytic Fe(2+) ion with FA and 5OHFA indicate the potency of these chelators to prevent the formation of (•)OH radicals via Fenton-like reactions. …”
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    Theoretical Study of Radical Inactivation, LOX Inhibition, and Iron Chelation: The Role of Ferulic Acid in Skin Protection against UVA Induced Oxidative Stress
  15. 2415
    “…(1) Background: Deferoxamine B (DFO) is the most widely used chelator for labeling of zirconium-89 ((89)Zr) to monoclonal antibody (mAb). …”
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    Re-Evaluations of Zr-DFO Complex Coordination Chemistry for the Estimation of Radiochemical Yields and Chelator-to-Antibody Ratios of (89)Zr Immune-PET Tracers
  16. 2416
    “…Furthermore, antioxidant and metal chelation activities of aerial parts and roots were investigated, revealing a potent activity as an antioxidant and high metal chelation capacity for heavy metals.…”
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    Comparative Volatile Profiling of Ludwigia stolonifera Aerial Parts and Roots Using VSE-GC-MS/MS and Screening of Antioxidant and Metal Chelation Activities
  17. 2417
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    Fe, N-Doped Metal Organic Framework Prepared by the Calcination of Iron Chelated Polyimines as the Cathode-Catalyst of Proton Exchange Membrane Fuel Cells
  18. 2418
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    Thiosemicarbazone Copper Chelator BLT-1 Blocks Apicomplexan Parasite Replication by Selective Inhibition of Scavenger Receptor B Type 1 (SR-BI)
  19. 2419
    “…Furthermore, the sequestering ability and metal chelating affinity of the ligands were investigated by the determination of pL(0.5) and pM parameters at different pH conditions. …”
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    Bifunctional 3-Hydroxy-4-Pyridinones as Potential Selective Iron(III) Chelators: Solution Studies and Comparison with Other Metals of Biological and Environmental Relevance
  20. 2420
    “…A series of chelated dehydroacetic acid–imine-based ligands L(1)H~L(4)H was synthesized by reacting dehydroacetic acid with 2-t-butylaniline, (S)-1-phenyl-ethylamine, 4-methoxylbenzylamine, and 2-(aminoethyl)pyridine, respectively, in moderate yields. …”
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    Ring-Opening Polymerization of ε-Caprolactone and Styrene Oxide–CO(2) Coupling Reactions Catalyzed by Chelated Dehydroacetic Acid–Imine Aluminum Complexes
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