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  1. 241
    “…Copper and iron are two essential metals that play significant roles in the rapid proliferation of cancer cells and several chelators have been studied to suppress the bioavailability of these metals in the cells. …”
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    Iron and Copper Intracellular Chelation as an Anticancer Drug Strategy
  2. 242
    por Bowman, Clive E.
    Publicado 2021
    “…Carpoglyphus lactis typifies a mite with tweezer-like chelae of very feeble adductive force. It is suggested that possible zoophagy (hypocarnivory) is associated with low chelal adductive force together with a small or large gape depending upon the size of the nematode being consumed. …”
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    Cheliceral chelal design in free-living astigmatid mites
  3. 243
    “…BACKGROUND: Phelan-McDermid syndrome (PMS) is a rare genetic disorder compromising the 22q13 terminal region and affecting SHANK3, a gene crucial to the neurobehavioural phenotype and strongly linked to autism (ASD) and intellectual disability (ID). …”
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    Characterisation of the clinical phenotype in Phelan-McDermid syndrome
  4. 244
    por Ben-Shushan, Shira, Miller, Yifat
    Publicado 2021
    “…In the past four decades, there has been extensive effort to design compound agents than can chelate metal ions with the aim of preventing the formation of the amyloid deposits. …”
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    Neuropeptides: Roles and Activities as Metal Chelators in Neurodegenerative Diseases
  5. 245
    “…Bidentate ligands can chelate to the same copper atom via η(2)-mode, forming a mono-cupra-cyclic compounds with at least one acute C-Cu-C angle. …”
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    C,C- and C,N-Chelated Organocopper Compounds
  6. 246
    “…In this study, we developed PSMA ligands with two different hybrid chelators and a modified linker. Both compounds have displayed a promising pharmacokinetic profile. (2) Methods: DATA(5m).SA.KuE and AAZTA(5).SA.KuE were synthesized. …”
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    Hybrid Chelator-Based PSMA Radiopharmaceuticals: Translational Approach
  7. 247
    “…This led to the hypothesis that iron chelation preserves the binding of tetracyclines to the bacterial ribosome. …”
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    Effect of iron chelation on anti-pseudomonal activity of doxycycline
  8. 248
    “…A study of bicyclic tetramates modified with a bulky ester, which leads to steric hindrance of distal chelating atoms as a route for the alteration of metal binding ability is reported. …”
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    Mediation of metal chelation in cysteine-derived tetramate systems
  9. 249
    “…The article presents the characteristics of stemness markers and their influence on the development and course of neoplastic disease. Available iron chelators were also described, and their effects on cancer cells and expression of stemness-related markers were analyzed.…”
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    The Impact of Iron Chelators on the Biology of Cancer Stem Cells
  10. 250
    “…Porphyrin ligands, showing a significant affinity for cancer cells, also have the ability to chelate metallic radioisotopes to form potential diagnostic radiopharmaceuticals. …”
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    Porphyrins as Chelating Agents for Molecular Imaging in Nuclear Medicine
  11. 251
    “…Herein, we report the synthesis of three new bifunctional heptadentate metal ion binding chelates derived from desferrioxamine B (DFO) linked to a tripeptide unit that comprises of a glutamic acid and two glycine residues. …”
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    Heptadentate chelates for (89)Zr-radiolabelling of monoclonal antibodies
  12. 252
    “…This current review evaluates insights into proteomics and metabolomics of metal chelation in food crops with special effects on the toxicity, tolerance, and partitioning of metals towards better health. …”
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    Insights to proteomics and metabolomics metal chelation in food crops
  13. 253
    “…Adding or improving the chelating abilities of existing drugs or finding new, nature-inspired chelating agents seems to be one of the major ways to ensure progress. …”
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    Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond
  14. 254
    “…In this study, peptides-calcium chelate derived from Crimson Snapper scales protein hydrolysates (CSPHs), and xylooligosaccharide (XOS)-peptides-calcium chelate prepared by transglutaminase (TGase) pathway, named CSPHs-Ca and XOS-CSPHs-Ca-TG, were used to explore the effects of glycosylation on their structural properties and osteogenic activity in vitro. …”
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    Characteristics and osteogenic mechanism of glycosylated peptides-calcium chelate
  15. 255
    “…Developments in bifunctional chelator design and application are then presented and grouped according to eight categories of bifunctional chelator: the macrocyclic chelators DOTA and TACN; the acyclic HBED, pyridinecarboxylates, siderophores, tris(hydroxypyridinones), and DTPA; and the mesocyclic diazepines.…”
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    Modern Developments in Bifunctional Chelator Design for Gallium Radiopharmaceuticals
  16. 256
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    Chelating chloride using binuclear lanthanide complexes in water
  17. 257
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    Phosphineoxide-Chelated Europium(III) Nanoparticles for Ceftriaxone Detection
  18. 258
    “…[(68)Ga]Ga(3+) can be introduced into receptor‐specific peptidic carriers via different chelators to obtain radiotracers for Positron Emission Tomography imaging and the chosen chelating agent considerably influences the in vivo pharmacokinetics of the corresponding radiopeptides. …”
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    Synthesis of a Bifunctional Cross‐Bridged Chelating Agent, Peptide Conjugation, and Comparison of (68)Ga Labeling and Complex Stability Characteristics with Established Chelators
  19. 259
    Publicado 1854
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    Medical Obituaries—Dr. McClellan—Dr. Cooke—Dr. Howard
  20. 260
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    Comorbidities in Chilean patients with psoriasis: a Global Healthcare Study on Psoriasis
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