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581por Nobre, Paula, Cabral, Maria de Fátima, Costa, Judite, Castro-Caldas, Margarida, Carvalho, Cristina, Branco, Vasco“…Current clinical approaches to mitigate the toxicity of MeHg rely on the use of chelators, such as meso-2,3-dimercaptosuccinic acid (DMSA) which largely replaced British anti-Lewisite or 2,3-dimercapto-1-propanol (BAL) as the prime choice. …”
Publicado 2019
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582por Gholami, Yaser H, Josephson, Lee, Akam, Eman A, Caravan, Peter, Wilks, Moses Q, Pan, Xiang-Zuo, Maschmeyer, Richard, Kolnick, Aleksandra, El Fakhri, Georges, Normandin, Marc D, Kuncic, Zdenka, Yuan, Hushan“…PURPOSE: Using our chelate-free, heat-induced radiolabeling (HIR) method, we show that a wide range of metals, including those with radioactive isotopologues used for diagnostic imaging and radionuclide therapy, bind to the Feraheme (FH) nanoparticle (NP), a drug approved for the treatment of iron anemia. …”
Publicado 2020
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583por Rychen, Guido, Aquilina, Gabriele, Azimonti, Giovanna, Bampidis, Vasileios, Bastos, Maria de Lourdes, Bories, Georges, Chesson, Andrew, Cocconcelli, Pier Sandro, Flachowsky, Gerhard, Gropp, Jürgen, Kolar, Boris, Kouba, Maryline, López Puente, Secundino, López Alonso, Marta, Mayo, Baltasar, Ramos, Fernando, Saarela, Maria, Villa, Roberto Edoardo, Wallace, Robert John, Wester, Pieter, Pechova, Alena, López‐Gálvez, Gloria, Mantovani, Alberto“…The additive ‘Zinc chelate of methionine sulfate’ is zinc chelated with methionine in a molar ratio 1:1, with a minimum zinc content of 19.1%. …”
Publicado 2017
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584“…In addition to metal chelation, bifunctional chelators have also been found to impact imaging outcomes due to their differences in stability, charge, hydrophilicity, etc. …”
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585“…OBJECTIVE: The aim of this study was to assess institutional delivery utilization and associated factors among mothers who gave birth in the last one year in Chelia District. Methodology. A community-based cross-sectional study design supplemented by a qualitative method was employed from March 15 to 30, 2018. …”
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586“…A better understanding of the pathophysiology of β-thalassemia in addition to key developments in optimizing transfusion programs and iron-chelation therapy has led to an increase in the life span of thalassemia patients and paved the way for new therapeutic strategies. …”
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587“…We critically highlight the properties of π-conjugated N^C-chelate organoboron materials. This is followed by a discussion on the potential applications of the new materials in opto-electronics (O-E) and other areas. …”
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588por Fu, Ji-jun, Guo, Jun-jie, Qin, Ai-ping, Yu, Xi-yong, Zhang, Qiang, Lei, Xue-ping, Huang, Yu-gang, Chen, Ming-yue, Li, Jie-xia, Zhang, Yu, Liu, Jing-ping, Dang, Yuan-ye, Wu, Dan, Zhao, Xiao-ya, Lin, Zhong-xiao, Lin, Yin-lei, Li, Song-pei, Zhang, Ling-yan“…METHODS: In this investigation, a small molecular bismuth chelate using diethylenetriaminepentaacetic acid (DPTA) as the chelating agent was proposed to be an ideal CT contrast agent. …”
Publicado 2020
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589por Chang, Li, Duan, Wenjie, Chen, Anguo, Li, Jianjun, Huang, Siqi, Tang, Huijuan, Pan, Gen, Deng, Yong, Zhao, Lining, Li, Defang, Zhao, Liang“…In this study, a series of novel polyacrylonitrile-based fibres with chelated Ag ions (referred to as Ag-SH-PANF) were prepared by a two-step chemical modification process: grafting and chelating. …”
Publicado 2020
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590por Tong, Kelvin K. H., Hanif, Muhammad, Lovett, James H., Hummitzsch, Katja, Harris, Hugh H., Söhnel, Tilo, Jamieson, Stephen M. F., Hartinger, Christian G.Enlace del recurso
Publicado 2020
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591por Bruchertseifer, Frank, Comba, Peter, Martin, Bodo, Morgenstern, Alfred, Notni, Johannes, Starke, Miriam, Wadepohl, Hubert“…It follows that nonadentate bispidines probably will be more suited as bifunctional chelators for (213)Bi(III)‐based radiopharmaceuticals. …”
Publicado 2020
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592por Brander, Søren, Horvath, Istvan, Ipsen, Johan Ø., Peciulyte, Ausra, Olsson, Lisbeth, Hernández-Rollán, Cristina, Nørholm, Morten H. H., Mossin, Susanne, Leggio, Leila Lo, Probst, Corinna, Thiele, Dennis J., Johansen, Katja S.“…PfCopC is not reduced by ascorbate but is a very strong Cu(II) chelator due to residues that interacts with the N-terminus. …”
Publicado 2020
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593por Marques, Eduardo Fernandes, Marceliano-Alves, Marília Fagury Videira, Pelegrine, Rina Andrea, Pinheiro, Sérgio Luiz, Bueno, Carlos Eduardo Da Silveira“…Objective This study aimed to evaluate the influence of chelating agents (EDTA, citric acid and Tetraclean) on glass fiber posts adhesion to root dentin. …”
Publicado 2020
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595por Chhabra, Ravneet, Saha, Aishwarya, Chamani, Ashkon, Schneider, Nicole, Shah, Riya, Nanjundan, Meera“…Thus, controlling microorganismal survival by limiting iron availability may prove feasible through the use of agents targeting their iron uptake pathways and/or use of iron chelators as a means to hinder development of infections. …”
Publicado 2020
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596“…Overall, the results, together with those from other studies, revealed serious limitations for each of the three hematological chelators, i.e., as potentially repurposed for treating infection/sepsis. …”
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597por Murata, Yoshiko, Yoshida, Masami, Sakamoto, Naho, Morimoto, Shiho, Watanabe, Takehiro, Namba, Kosuke“…Iron is an essential metal for all living organisms that is absorbed in the intestinal cells as a heme-chelated or free form. It is unclear how important plant-derived chelators, such as nicotianamine (NA), an organic small molecule that is ubiquitous in crops, vegetables, and various other foods, contribute to iron bioavailability in mammals. …”
Publicado 2020
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598“…To this end, triglycine (HG(3)), a tripeptide of the amino acid glycine, was chosen as a chelating ligand for magnesium, given its natural occurrence and water solubility, and entropically-driven metal binding. …”
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599“…Nonadherence to iron chelation therapy (ICT) remains a long-standing and serious issue in thalassemia, especially in resource-constrained developing countries. …”
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600por Argenziano, Maura, Tortora, Chiara, Paola, Alessandra Di, Pota, Elvira, Martino, Martina Di, Pinto, Daniela Di, Leva, Caterina Di, Rossi, Francesca“…Eltrombopag (ELT), a thrombopoietin receptor agonist used in immunethrombocytopenia, shows anticancer properties related to its emerging iron chelating properties. We compare the anticancer effect of classically used cytarabine with DFX and ELT effects in a pediatric AML cell line, THP-1, in order to identify innovative and more effective therapeutic strategies. …”
Publicado 2021
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