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601por Byrne, Fergal P., Assemat, Jamie M. Z., Stanford, Amy E., Farmer, Thomas J., Comerford, James W., Pellis, Alessandro“…The application of the synthesized polymers as effective metal chelators in biphasic, green solvent systems was also described, together with the characterisation of the synthesised materials.…”
Publicado 2021
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602por Straathof, Natan J. W., Magnus, Charlotte B., Zhuravlev, Fedor, Jensen, Andreas I.“…This is due in part to a lack of compatible bifunctional chelators. These allow for the practical bioconjugation to targeting vectors, in turn enabling radiolabeling. …”
Publicado 2021
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603por Zou, Yatao, Teng, Pengpeng, Xu, Weidong, Zheng, Guanhaojie, Lin, Weihua, Yin, Jun, Kobera, Libor, Abbrent, Sabina, Li, Xiangchun, Steele, Julian A., Solano, Eduardo, Roeffaers, Maarten B. J., Li, Jun, Cai, Lei, Kuang, Chaoyang, Scheblykin, Ivan G., Brus, Jiri, Zheng, Kaibo, Yang, Ying, Mohammed, Omar F., Bakr, Osman M., Pullerits, Tönu, Bai, Sai, Sun, Baoquan, Gao, Feng“…Here, we reveal the largely ignored yet critical role of the chelate effect on governing crystallization dynamics of perovskite emitters and mitigating trap-mediated non-radiative losses. …”
Publicado 2021
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604por Kuźmicka, Weronika, Moskalik, Aneta, Manda-Handzlik, Aneta, Demkow, Urszula, Wachowska, Małgorzata, Ciepiela, Olga“…The aim of this study was to assess how lack of iron and zinc generated by ion sequestration using chelators affects NET release. Neutrophils were isolated from whole blood or buffy coats of healthy blood donors by density gradient centrifugation and incubated with zinc chelators: 20 µM N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine (TPEN), 40 µM diethylenetriaminepentaacetic acid (DTPA) or iron chelators: 400 µM deferoxamine mesylate salt (DFO) and 50 µM iminodiacetic acid (IDA). …”
Publicado 2021
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605por Srivastava, Siddharth, Condy, Emma, Carmody, Erin, Filip-Dhima, Rajna, Kapur, Kush, Bernstein, Jonathan A., Berry-Kravis, Elizabeth, Powell, Craig M., Soorya, Latha, Thurm, Audrey, Buxbaum, Joseph D., Sahin, Mustafa, Kolevzon, Alexander“…BACKGROUND: Phelan McDermid syndrome (PMS) is a neurogenetic condition associated with a high prevalence of intellectual disability (ID) and autism spectrum disorder (ASD). …”
Publicado 2021
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606por Lachowicz, Joanna I., Pichiri, Giusi, Piludu, Marco, Fais, Sara, Orrù, Germano, Congiu, Terenzio, Piras, Monica, Faa, Gavino, Fanni, Daniela, Dalla Torre, Gabriele, Lopez, Xabier, Chandra, Kousik, Szczepski, Kacper, Jaremko, Lukasz, Ghosh, Mitra, Emwas, Abdul-Hamid, Castagnola, Massimo, Jaremko, Mariusz, Hannappel, Ewald, Coni, Pierpaolo“…We state the hypothesis that Tβ4 is an endogenous iron chelator and take part in iron homeostasis in the ferroptosis process. …”
Publicado 2022
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607por Blumberg, Markus, Al-Ameed, Karrar, Eiselt, Erik, Luber, Sandra, Mamat, Constantin“…Two sets of functionalised calix[4]arenes, either with a 1,3-crown ether bridge or with an open-chain oligo ether moiety in 1,3-position were prepared and further equipped with additional deprotonisable sulfonamide groups to establish chelating systems for selected cations Sr(2+), Ba(2+), and Pb(2+) ions. …”
Publicado 2022
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608“…Hydroxypyridinones (HPs) are recognized as excellent chemical tools for engineering a diversity of metal chelating agents, with high affinity for hard metal ions, exhibiting a broad range of activities and applications, namely in medical, biological and environmental contexts. …”
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609“…Upon chelation, viscous oils are converted to (very) soft elastomers. …”
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610“…Phytoextraction of Pb using switchgrass (Panicum virgatum L.), a second-generation biofuel crop, is typically enhanced by soil chelation. The effectiveness of four different chelating agents, phytic acid (inositol hexaphosphate), citric acid, NTA (nitrilotriacetic acid), and EDTA (ethylenediaminetetraacetic acid) was examined in pot culture. …”
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611por Nevado, Julián, García-Miñaúr, Sixto, Palomares-Bralo, María, Vallespín, Elena, Guillén-Navarro, Encarna, Rosell, Jordi, Bel-Fenellós, Cristina, Mori, María Ángeles, Milá, Montserrat, del Campo, Miguel, Barrúz, Pilar, Santos-Simarro, Fernando, Obregón, Gabriela, Orellana, Carmen, Pachajoa, Harry, Tenorio, Jair Antonio, Galán, Enrique, Cigudosa, Juan C., Moresco, Angélica, Saleme, César, Castillo, Silvia, Gabau, Elisabeth, Pérez-Jurado, Luis, Barcia, Ana, Martín, Maria Soledad, Mansilla, Elena, Vallcorba, Isabel, García-Murillo, Pedro, Cammarata-Scalisi, Franco, Gonçalves Pereira, Natálya, Blanco-Lago, Raquel, Serrano, Mercedes, Ortigoza-Escobar, Juan Dario, Gener, Blanca, Seidel, Verónica Adriana, Tirado, Pilar, Lapunzina, Pablo“…Phelan-McDermid syndrome (PMS, OMIM# 606232) results from either different rearrangements at the distal region of the long arm of chromosome 22 (22q13.3) or pathogenic sequence variants in the SHANK3 gene. …”
Publicado 2022
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612“…The design of new and efficient chelators that can remove aluminium(iii), a metal with increasing recognition as a potential toxic agent, from biological systems is an area of high therapeutic relevance. …”
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613por Isenstein, Emily L., Grosman, Hannah E., Guillory, Sylvia B., Zhang, Yian, Barkley, Sarah, McLaughlin, Christopher S., Levy, Tess, Halpern, Danielle, Siper, Paige M., Buxbaum, Joseph D., Kolevzon, Alexander, Foss-Feig, Jennifer H.“…Phelan-McDermid Syndrome (PMS) is a rare genetic disorder caused by deletion or sequence variation in the SHANK3 gene at terminal chromosome 22 that confers high likelihood of comorbid autism spectrum disorder (ASD). …”
Publicado 2022
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614“…For 13 of them (designated ferroverdins C2, C3, D, D2, D3, E, F, G, H, CD, DE, DF, and DG), we could elucidate their structure, and for the other 17 new ferroverdins, ambiguity remains for one of the three ligands. p-formylphenyl-3,4-NHBA, p-benzoic acid-3,4-NHBA, 3,4-NHBA, p-phenylpropionate-3,4-NHBA, and p-phenyacetate-3,4-NHBA were identified as new alternative chelators for Fe(2+)-binding, and two compounds (C3 and D3) are the first reported ferroverdins that do not recruit p-vinylphenyl-3,4-NHBA. …”
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615por Huang, Wen, Lao, Linhui, Deng, Yuliang, Li, Ziwei, Liao, Wanwen, Duan, Shan, Xiao, Suyao, Cao, Yong, Miao, Jianyin“…In this study, the preparation of casein phosphopeptide calcium chelate (CPP-Ca) was optimized on the basis of previous studies, and its peptide-calcium chelating activity was characterized. …”
Publicado 2022
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616por An, Jiulong, Zhang, Yinxiao, Ying, Zhiwei, Li, He, Liu, Wanlu, Wang, Junru, Liu, Xinqi“…The stability and safety of calcium–peptide chelates are discussed in this paper, the intestinal absorption pathways of calcium elements and peptides are described, and the bioavailability of calcium–peptide chelates, both in vitro and in vivo, is also introduced. …”
Publicado 2022
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617por Cuffaro, Doretta, Ciccone, Lidia, Rossello, Armando, Nuti, Elisa, Santamaria, Salvatore“…The first aggrecanase inhibitors targeted the active site by chelation of the catalytic zinc ion. Due to the generally disappointing performance of zinc-chelating inhibitors in preclinical and clinical studies, inhibition strategies tried to move away from the active-site zinc in order to improve selectivity. …”
Publicado 2022
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618“…The chelating thiol dimercaptosuccinate (DMSA) and the traditional agent D-penicillamine (PSH) are effective in enhancing the urinary excretion of copper (Cu) and lead (Pb) in poisoned individuals. …”
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619por Nikitin, Evgeny, Mironova, Ekaterina, Shpakovsky, Dmitry, Gracheva, Yulia, Koshelev, Daniil, Utochnikova, Valentina, Lyssenko, Konstantin, Oprunenko, Yury, Yakovlev, Dmitry, Litvinov, Roman, Seryogina, Mariya, Spasov, Alexander, Milaeva, Elena“…A novel polydentate chelating antioxidant ligand and series of organotin complexes on its base were synthesized and characterized by NMR (1)H, (13)C, (119)Sn, IR spectroscopy, X-ray, and elemental analysis. …”
Publicado 2022
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620“…METHODS: The objective of the study was to examine the impact of iron chelation on the growth of AB in vitro and in vivo. …”
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