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  1. 9901
    “…In cultured human cardiomyocytes, Cu chelation blocks insulin-like growth factor (IGF)-1– or Cu-stimulated VEGF expression, which is relieved by addition of excess Cu. …”
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    Dietary copper supplementation reverses hypertrophic cardiomyopathy induced by chronic pressure overload in mice
  2. 9902
    “…The hemolysis induced by CVF with frog serum, as in the higher vertebrates, was inhibited when sera were pretreated with known C inhibitors including heat, chelators, endotoxin, immune complexes, and CVF itself. …”
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    COMPLEMENT AND COMPLEMENT-LIKE ACTIVITY IN LOWER VERTEBRATES AND INVERTEBRATES
  3. 9903
    “…Noninvasive photoactivation of a calcium chelator (Diazo-2) was used to specifically disrupt the transient rise in calcium induced by serum stimulation of starved Swiss 3T3 cells. …”
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    Calcium-dependent regulation of the cell cycle via a novel MAPK–NF-κB pathway in Swiss 3T3 cells
  4. 9904
    “…This indicates that the selective permeabilities of this unique channel class may result from novel mechanisms, including complex van der Waals interactions of permeants with the pore wall, rather than mechanisms involving fixed charges or chelation chemistry as reported for other ion channels.…”
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    Identification of amino acid residues lining the pore of a gap junction channel
  5. 9905
    “…Electrophysiological analyses revealed that NMDA receptor–mediated synaptic responses in CA3 proximal stratum radiatum were inhibited in the immediate aftermath of MF activation and that this inhibition was no longer observed in the presence of a Zn(2+)-chelating agent. Thus, Zn(2+) serves as a spatiotemporal mediator in imprinting the history of MF activity in contiguous hippocampal networks. …”
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    Mossy fiber Zn(2+) spillover modulates heterosynaptic N-methyl-d-aspartate receptor activity in hippocampal CA3 circuits
  6. 9906
    “…These filaments could be disassembled by the addition of a chelating agent. A simple head-to-tail model is proposed for filament formation that explains the metal ion-dependency. …”
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    Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides
  7. 9907
    Publicado 1987
    “…It is shown that external Ca2+ is obligatory for both the TCR-triggered and for the PMA/A23187-triggered exocytosis, since Ca2+ chelators and divalent cations that compete with Ca2+ for A23187 can inhibit exocytosis of granules. …”
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    Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes
  8. 9908
    Publicado 1995
    “…NO was also shown to alter cellular respiration and decrease the concentration of the antioxidant glutathione to a residual level of 15-20% in bacterial cells. The iron chelator desferrioxamine did not stop the action of NO on respiration and glutathione decrease, yet it prevented the NO/H2O2 synergistic cytotoxicity, implicating metal ions as critical participants in the NO/H2O2 cytocidal mechanism. …”
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    Nitric oxide potentiates hydrogen peroxide-induced killing of Escherichia coli
  9. 9909
    Publicado 1996
    “…Both human and A. fumigatus MnSOD coding sequences were expressed in Escherichia coli as [His]6-tagged fusion proteins and purified by Ni(2+)-chelate affinity chromatography. The two recombinant MnSODs were both recognized by IgE antibodies from subjects allergic to the A. fumigatus MnSOD and elicited specific immediate type allergic skin reactions in these individuals. …”
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    Humoral and cell-mediated autoimmunity in allergy to Aspergillus fumigatus
  10. 9910
    “…Studies on hydrogen peroxide decomposition indicated that these ions act probably by accelerating the hydrogen perioxide oxidation of glutathione. The chelating agent, ethylenediaminetetraacetic acid disodium salt, inhibited the oxidation of GSH exposed to high oxygen pressure for 14 hours. …”
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    THE PRODUCTION OF HYDROGEN PEROXIDE BY HIGH OXYGEN PRESSURES
  11. 9911
    “…Surface cathepsin B eluted from live CTL after degranulation by calcium chelation is the single chain processed form of active cathepsin B. …”
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    Surface Cathepsin B Protects Cytotoxic Lymphocytes from Self-destruction after Degranulation
  12. 9912
    Publicado 1986
    “…Like the macroscopic conductance, channel activity was reduced by light adaptation but enhanced by the intracellular injection of the calcium chelator EGTA. The latter observation indicates that channel activation was not a secondary result of the light-induced rise in intracellular calcium. …”
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    Ion channels activated by light in Limulus ventral photoreceptors
  13. 9913
    por Grégoire, Charles
    Publicado 1957
    “…Replicas of these surfaces were prepared before and after etching of graded heaviness, induced by a chelating agent (sequestrene NA 2, titriplex III). …”
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    TOPOGRAPHY OF THE ORGANIC COMPONENTS IN MOTHER-OF-PEARL
  14. 9914
    “…NTA was shown previously to 'free' iron to promote lipid peroxidation and an iron chelate of NTA is known to be carcinogenic to the kidney. …”
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    Induction of mesothelioma by intraperitoneal injections of ferric saccharate in male Wistar rats.
  15. 9915
    “…A better choice was the use of high M(r) alkali ion polyethylene glycol–400 (PEG-400) crown ether type chelates. PEG-400 complexes alkali ions including rubidium and other alkaliions impeding the diffusion of their basic counter ions into lower varnish or paint layers. …”
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    Alkali-Ion-Crown Ether in Art and Conservation: The Applied Bioinorganic Chemistry Approach
  16. 9916
    “…The decomposition course and steps were analyzed and the activation parameters of the nonisothermal decomposition are determined. The isolated metal chelates have been screened for their antimicrobial activities and the findings have been reported and discussed in relation to their structures.…”
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    Synthesis, Characterization, and Biological Activity of N(1)-Methyl-2-(1H-1,2,3-Benzotriazol-1-y1)-3-Oxobutan- ethioamide Complexes with Some Divalent Metal (II) Ions
  17. 9917
    “…An X-ray crystallographic study has shown PhBi(MeOx)(2) to be a five coordinate monomer with distorted square pyramidal stereochemistry. Chelating MeOx ligands have a cisoid arrangement in the square plane and the phenyl group is apical. …”
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    Preparation and Anti-Tumour Activity of Some Arylbismuth(III) Oxine Complexes
  18. 9918
    “…In our study, we investigated the regulation of frataxin expression by iron and demonstrated that frataxin mRNA levels decrease significantly in multiple human cell lines treated with the iron chelator, desferal (DFO). In addition, frataxin mRNA and protein levels decrease in fibroblast and lymphoblast cells derived from both normal controls and from patients with FA when treated with DFO. …”
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    Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia
  19. 9919
    “…The palladium (II) bis-chelate Pd (L(1−3))(2) and platinum (II) tetranuclear Pt(4)(L(4))(4) complexes of benzaldehyde thiosemicarbazone derivatives have been synthesized, and characterized by elemental analysis and IR, FAB(+)-mass and NMR ((1)H, (13)C) spectroscopy. …”
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    Synthesis, Characterization, and In Vitro Cytotoxic Activities of Benzaldehyde Thiosemicarbazone Derivatives and Their Palladium (II) and Platinum (II) Complexes against Various Human Tumor Cell Lines
  20. 9920
    “…The second and third stages, which are kinetically indistinguishable, do not depend on the concentrations of ligand and chromium(III), accounting for isomerization and chelation processes, respectively. The corresponding activation parameters are ΔH (2(obs)) (≠) = 44.5 ± 5.0 kJ mol(−1), ΔS (2(obs)) (≠) = −175.8 ± 70.3 J mol(−1) K(−1). …”
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    Reaction of Chromium(III) with 3,4-Dihydroxybenzoic Acid: Kinetics and Mechanism in Weak Acidic Aqueous Solutions
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