“…The use of the iron chelator, deferasirox, as adjunctive therapy also improved outcomes in animal models of mucormycosis. …”
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“…Both Cd(2+) ions display coordination polyhedra with a distorted octa­hedral geometry that includes two pyridine N atoms from bridging and terminal nicotinate anions, two amine N atoms from chelating ethylene­diamine ligands, carboxylate O atoms from bridging nicotinate anions and water O atoms. …”
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“…In addition, dexrazoxane was capable to inhibit the generation superoxide and hydroxyl radicals in iron free reaction system, indicating that the antioxidant properties of dexrazoxane were not solely dependent on iron chelation. Thus the application of dexrazoxane should not be limited to doxorubicin-induced cardiotoxicity. …”
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“…The title compound, [Ni(C(8)H(10)F(3)O(2))(2)(CH(4)O)(1.55)(H(2)O)(0.45)][Ni(C(8)H(10)F(3)O(2))(2)(CH(4)O)(0.51)(H(2)O)(1.49)], is an octa­hedral nickel(II) complex with two acetyl­acetonate-like 1,1,1-trifluoro-5,5-dimethyl­hexane-2,4-dionate ligands. The two chelating ligands are in cis positions with respect to each other and the remaining two adjacent coordination sites are taken up by water and methanol donor mol­ecules. …”
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“…A benzene C and the azomethine N atom chelate the Hg(II) atoms with weak intra­molecular Hg⋯N bonding distances of 2.735 (3) and 2.739 (3) Å, respectively. …”
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“…Each Pb(II) cation is hepta­coordinated and chelated by four carboxyl­ate O atoms from two MBA ligands. …”
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“…The (py)(2)C(OH)O ligand acts in an η(1):η(3):η(1):μ(3) manner, forming two five-membered ZnNCCO chelating rings with two different Zn(II) atoms sharing a common C—O bond, and an alkoxide-type bond to a third Zn(II) ion. …”
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“…The K(+) ion is 7-coordinated by the oxygen atoms of two water mol­ecules and by five oxygen atoms of four carboxyl­ate groups, one of which is chelating. The extended structure can be described as a binodal network in which each K(+) is a six-connected node, bonding to four carboxyl­ate groups and two bridging water mol­ecules, and the 2,2′-bipyridyl-5,5′-dicarboxyl­ate linkers are eight-connected nodes, with each carboxyl­ate group bridging four metal centers. …”
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“…The software package for detecting GIs can be accessed at http://www.esu.edu/cpsc/che_lab/software/GIDetector/.…”
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“…The Cu(II) atom is coordinated by two pydc dianions acting as tridentate ligands, and forming five-membered chelate rings with copper(II) as the central atom. …”
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“…Each Sb(III) atom is six-coordinated by one chelating 4-oxidopyridine-2,6-dicarboxyl­ate ligand, one water mol­ecule, one OH group and one bridging O atom from a neighboring carboxyl­ate group in a distorted penta­gonal-pyramidal geometry, with the OH group at the apical position. …”
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“…The compound crystallizes as a racemate, i.e. a mixture of (R (N2),C (Sb1)) and (S (N2),A (Sb1)) isomers with respect to planar chirality induced by the coordinating N atom and chelate-induced Sb chirality. These isomers are associated through C(phen­yl)—H⋯Cl/Br hydrogen bonds, forming a three-dimensional architecture.…”
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“…The aptamer adopts a characteristic structure fit to hFc1 that is stabilized by a calcium ion, and the binding activity of the aptamer can be controlled many times by calcium chelation and addition. Importantly, the aptamer–hFc1 interaction involves mainly van der Waals contacts and hydrogen bonds rather than electrostatic forces, in contrast to other known aptamer–protein complexes. …”
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“…Enzyme activity was inhibited by the substrate mimics, levulinic acid and succinylacetone, and by chelating agents. PBGS behaved as a relatively heat-stable octameric complex of 292.3 kDa composed of 36.5 kDa subunits. …”
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“…HIV-1 infection was detected using a double antigen sandwich format wherein anti-HIV-1 antibodies were captured using an in vivo biotinylated version of a chimeric HIV-1 antigen and revealed using the same antigen labeled with Tb(3+ )chelate. Hepatitis B surface antigen (HBsAg), which served as the marker of HBV infection, was detected in a double antibody sandwich using two monoclonal antibodies (mAbs), one chemically biotinylated to capture, and the other labeled with Eu(3+ )nanoparticles, to reveal. …”
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“…The K(+) ion is coordinated by the O atoms of the OH groups, leading to a six-membered chelate ring that adopts a very distorted boat conformation. …”
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“…Given these factors, the endogenous peptide carnosine may be potentially beneficial in the treatment of AD because of its free-radical scavenger and metal chelating properties. METHODOLOGY: In this study, we explored the effect of L-carnosine supplementation in the 3xTg-AD mouse, an animal model of AD that shows both Aβ- and tau-dependent pathology. …”
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“…The enrichment of heavy isotopes at the roots was attributed to Zn uptake mediated by transporter proteins under Zn-sufficient conditions and to chelation and compartmentation in Zn excess. The isotopically lighter Zn in shoots and leaves is consistent with long-distance root to shoot transport. …”
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“…The presence of two bidentate chelating ligands determines the chirality of the Ti(IV) atom. …”
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“…METHODS: Based on the structure of the 2-fluoro-2-deoxy-D-glucose molecule ((18)FDG), a new compound consisting of D-glucose (1.1 nm) conjugated to a well-known chelator, diethylenetriamine penta-acetic acid (DTPA), was synthesized, labeled with Gd(3+), and examined in vitro and in vivo. …”
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