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981por van Hattem, Jessica, Maes, Philip, Esterhuizen, Tonya Marianne, Devos, Ann, Ruppert, Martin, van Heerden, Jaques“…The aim of this study was to evaluate erythrocytapheresis, either as a standalone therapy or in combination with iron chelation therapy, in children and young adults with hemoglobinopathies in whom current iron chelation therapy is not sufficient in decreasing the iron overload during management. …”
Publicado 2023
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982por D’Accolti, Maria, Bellotti, Denise, Dzień, Emilia, Leonetti, Carlotta, Leveraro, Silvia, Albanese, Valentina, Marzola, Erika, Guerrini, Remo, Caselli, Elisabetta, Rowińska-Żyrek, Magdalena, Remelli, Maurizio“…To improve the plasma stability of calcitermin, a metal-chelating AMP present in the human respiratory tract and investigated in the present study, C- and/or N- terminal modifications have been introduced in the native sequence. …”
Publicado 2023
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983
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984“…Previously it has been shown that bloodstream-form trypanosomes are sensitive to the iron chelator deferoxamine. In this study the effect of 13 iron chelators on the growth of Trypanosoma brucei, T. congolense and human HL-60 cells was tested in vitro. …”
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985
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986“…The effects of the iron chelators ethylenediaminetetraacetic acid (EDTA) and desferrioxamine (DEF) were assessed. …”
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987Publicado 1975“…The use of liposomes as carriers seems to be a useful tool for intracellular delivery of chelating agents or drugs in general.…”
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988“…Copper(II) complexes of amino acids and peptides containing the chelating bis(imidazolyl) residues have been reviewed. …”
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989
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990por Gattermann, Norbert“…These guidelines show that the approaches to managing iron overload in patients with MDS are region specific, differing in their recommendations for when iron chelation therapy should be initiated and strategies for the ongoing management of iron overload. …”
Publicado 2008
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991“…The objective of this study was to determine the efficacy of dietary supplementation with the metal chelators, trientine or citric acid, in preventing the development of cardiomyopathy in the Zucker diabetic rat. …”
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992
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993“…BACKGROUND: The purpose of this study was to assess the in vivo ability of glucosaminic acid-cobalt (II) chelate to reduce glycemia. METHODS: Different concentrations of chelate solution were administrated to mice with diabetes induced by streptozotocin. …”
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994“…BACKGROUND: Trials of iron chelator regimens have increased the treatment options for cardiac siderosis in beta-thalassemia major (TM) patients. …”
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995“…The cytotoxic effects of these iron chelators against Hela cancer cells were also evaluated. …”
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996por Pereira, Leonardo Victor Barbosa, Shimizu, Maria Heloisa Massola, Rodrigues, Lina Paola Miranda Ruiz, Leite, Cláudia Costa, Andrade, Lúcia, Seguro, Antonio Carlos“…The aim of this study was to evaluate the effect of Gd-chelate on renal function, iron parameters and oxidative stress in rats with CRF and a possible protective effect of the antioxidant N-Acetylcysteine (NAC). …”
Publicado 2012
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997por Mohammadpour, M., Sadeghi, A., Fassihi, A., Saghaei, L., Movahedian, A., Rostami, M.“…All of the synthesized compounds had very close chelating ability, compounds containing N(1)-CH3 hydroxypyridinone ring were stronger chelating agents.…”
Publicado 2012
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998“…The effect of TPEN on NAADP-induced Ca(2+) release was not due to an increase in the luminal pH or chelation of trace metals since it could not be mimicked by NH(4)Cl or phenanthroline. …”
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999por Veríssimo, Monica Pinheiro de Almeida, Loggetto, Sandra Regina, Fabron Junior, Antonio, Baldanzi, Giorgio Roberto, Hamerschlak, Nelson, Fernandes, Juliano Lara, Araujo, Aderson da Silva, Lobo, Clarisse Lopes de Castro, Fertrin, Kleber Yotsumoto, Berdoukas, Vasilios Antonios, Galanello, Renzo“…In the absence of an iron chelating agent, patients with beta-thalassemia on regular transfusions present complications of transfusion-related iron overload. …”
Publicado 2013
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1000por Soh, Nobuaki“…This review describes the advances in chemical labeling of proteins, especially highlighting the metal-chelation methodology.…”
Publicado 2008
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