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10501por Budy, Hendrik, Kaese, Thomas, Bolte, Michael, Lerner, Hans‐Wolfram, Wagner, Matthias“…Two subvalent, redox‐active diborane(4) anions, [3](4−) and [3](2−), carrying exceptionally high negative charge densities are reported: Reduction of 9‐methoxy‐9‐borafluorene with Li granules without stirring leads to the crystallization of the B(sp(3))−B(sp(2)) diborane(5) anion salt Li[5]. [5](−) contains a 2,2′‐biphenyldiyl‐bridged B−B core, a chelating 2,2′‐biphenyldiyl moiety, and a MeO substituent. …”
Publicado 2021
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10502por Lee, Yi-Nan, Wang, Hsueh-Hsiao, Su, Cheng-Huang, Lee, Hsin-I, Chou, Yen-Hung, Hsieh, Chin-Ling, Liu, Wen-Ting, Shu, Kuo-Tung, Chang, Kai-Ting, Yeh, Hung-I, Wu, Yih-Jer“…Here, we established an accelerated senescence model by treating EPCs with deferoxamine (DFO), an FDA-approved iron chelator. Four days of low-dose (3 μM) DFO induced senescent phenotypes in EPCs, including a senescent pattern of protein expression, impaired mitochondrial bioenergetics, altered mitochondrial protein levels and compromised angiogenic activity. …”
Publicado 2021
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10503por Wang, Tingting, Jiang, Zhiming, Wang, Yiya, Wu, Hao, Fang, Yan, Dong, Weiliang, Wu, Bin, Ma, Jiangfeng, Jiang, Min“…Moreover, L-dextran was oxidized with NaOH and chelated with ferric trichloride, and an OL-dextran-iron complex was synthesized with a high iron-loading potential of 33.5% (w/w). …”
Publicado 2021
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10504por Gluba-Brzózka, Anna, Franczyk, Beata, Rysz-Górzyńska, Magdalena, Rokicki, Robert, Koziarska-Rościszewska, Małgorzata, Rysz, Jacek“…The most important factors promoting such alterations involve iron overload, phenotypical and functional abnormalities of immune system cells resulting from chronic inflammation oxidative stress, multiple blood transfusion, iron chelation therapy, and splenectomy. Unravelling the mechanisms underlying immune deficiency in β-thalassemia patients may enable the designing of appropriate therapies for this group of patients.…”
Publicado 2021
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10505por Sun, Fang, Ye, Xin-Lu, Wang, Yu-Bo, Yue, Ming-Li, Li, Ping, Yang, Liu, Liu, Yu-Long, Fu, Ying“…Glyphosate exhibited a stronger chelation with Cu(2+) than NPA and the system released free NPA through competitive coordination. …”
Publicado 2021
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10506por Droste, Annika, Chaves, Gustavo, Stein, Stefan, Trzmiel, Annette, Schweizer, Matthias, Karl, Hubert, Musset, Boris“…Our results strongly suggest the essential interconnection of H(V)1 and NOX2 during the respiratory burst of phagocytes. Zinc chelation during the time course of the experiments postulates that zinc leads to an irreversible termination of the respiratory burst over time. …”
Publicado 2021
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10507“…Due to quercetin’s inherent metal-chelating ability, (Ca+Mg)/Si increased with quercetin concentration. …”
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10508por Rukavina, Iva, Rodrigues, Maria João, Pereira, Catarina G., Mansinhos, Inês, Romano, Anabela, Ślusarczyk, Sylwester, Matkowski, Adam, Custódio, Luísa“…NADES and conventional extracts were made by an ultrasound-assisted procedure and evaluated for in vitro antioxidant properties by the radical scavenging activity (RSA) on the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical, oxygen radical absorbance capacity (ORAC), and copper chelating activity (CCA). Samples were profiled by liquid chromatography (LC)-electrospray ionization (ESI)-QTOF-MS analysis. …”
Publicado 2021
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10509“…In addition, two new siderophore analogues chelating gallium ions (Ga(3+)), Ga (III)-acremonpeptide E (7) and Ga (III)-acremonpeptide F (8), using isolated acremonpeptides E and F, were prepared. …”
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10510por Cappai, Rosita, Crisponi, Guido, Sanna, Daniele, Ugone, Valeria, Melchior, Andrea, Garribba, Eugenio, Peana, Massimiliano, Zoroddu, Maria Antonietta, Nurchi, Valeria Marina“…The good chelating properties of hydroxypyrone (HPO) derivatives towards oxidovanadium(IV) cation, V(IV)O(2+), constitute the precondition for the development of new insulin-mimetic and anticancer compounds. …”
Publicado 2021
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10511por Sen, Amarnath“…The enhanced fungal virulence in COVID-19 can be mitigated by correcting the melatonin deficiency as melatonin can prevent iron acquisition of the mucor species and inhibit their morphological transition from the yeast to the virulent hyphal form, given the fact that melatonin is an iron chelator, calmodulin blocker and inhibitor of myeloperoxidase as well as inhibitor of ferroptosis and pyroptosis. …”
Publicado 2022
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10512“…This is because OTF has two iron binding sites, so it has a strong metal chelating ability. The present study aimed to evaluate the improved immune-enhancing activities of OTF hydrolysates produced using bromelain, pancreatin, and papain. …”
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10513“…The mainstay of treatment for most patients remains regular blood transfusions and iron chelation. This conventional therapy has many limitations and challenges. …”
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10514por Lavin, Christopher V., Abbas, Darren B., Fahy, Evan J., Lee, Daniel K., Griffin, Michelle, Diaz Deleon, Nestor M., Mascharak, Shamik, Chen, Kellen, Momeni, Arash, Gurtner, Geoffrey C., Longaker, Michael T., Wan, Derrick C.“…The iron chelator, deferoxamine (DFO), has been shown to potentially improve dermal radiation‐induced fibrosis (RIF) in mice through increased angiogenesis and reduced oxidative damage. …”
Publicado 2021
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10515por Teofilovic, Branislava, Golocorbin-Kon, Svetlana, Stilinovic, Nebojsa, Grujic-Letic, Nevena, Raškovic, Aleksandar, Mooranian, Armin, Al-Salami, Hani, Mikov, Momir“…Animals were treated with water extract of Ocimum basilicum in microvesicles and with combination of basil extracts and 3α,7α-dihydroxy-12-keto-5-cholanate, also known as 12-monoketocholic acid (MKC) acid in microvesicles for 7 days. …”
Publicado 2021
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10516por Vynohradov, Oleksandr S., Pavlenko, Vadim A., Kucheriv, Olesia I., Golenya, Irina A., Petlovanyi, Denys, Shova, Sergiu“…The pyrazole-based ligands are bidentate coordinated, leading to the formation of two five-membered chelate rings. The coordination geometry of both copper atoms (ON(2)Cl(3)) can be described as distorted octahedral on account of the acetonitrile coordination. …”
Publicado 2021
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10517por AKYÜZ, Esin“…The prooxidant activities were evaluated via measuring the absorption at 450 nm wavelength of the Cu(I)‒neocuproine chelate formed by extraction of protein-bound Cu(I) with neocuproine reagent. …”
Publicado 2021
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10518“…In this study, using various nuclease assays and bioinformatics analysis, we report that the recombinant Cas1 (LinCas1) possesses metal-ion dependent DNase activity, which is inhibited upon substitution or chelation of metal-ion and/or interaction with recombinant Cas2 (LinCas2) of L. interrogans. …”
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10519“…Compared with chromium ions, chitosan fibers have better adsorption of copper ions, which is mainly because the amino groups in chitosan fibers can have good chelation with copper ions. SEM, FTIR, XRD were used to characterize the adsorption of copper ions by chitosan fibers, and the mechanism of the adsorption of metal ions by chitosan fibers was explored.…”
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10520por Dorst, Daphne N., Boss, Marti, Rijpkema, Mark, Walgreen, Birgitte, Helsen, Monique M. A., Bos, Desirée L., van Bloois, Louis, Storm, Gerrit, Brom, Maarten, Laverman, Peter, van der Kraan, Peter M., Buitinga, Mijke, Koenders, Marije I., Gotthardt, Martin“…For radiolabeling, a chelator was also incorporated. RAW 264.7 cells were incubated with liposomes with or without IRDye700DX and exposed to 689 nm light. …”
Publicado 2021
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