“…The DPPH assay showed that OESA possesses a stronger antioxidant activity (84%) at 1 mg/mL while the FRAP method showed a strong metal ion chelating activity (90%) at 1 mg/mL. The low IC(50) values, obtained by two different methods, implies that OESA has a noticeable effect on scavenging free radicals comparable to standards. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, when coupling with chelating agents (e.g., EDTA) to target the biofilm architecture by breaking or weakening the EPS protection, much enhanced photoinactivation of biofilm-associated cells by CDots was achieved. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The research results showed that GNP had fairly strong scavenging activities on 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical, hydroxyl radical, and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and had Fe(2+)-chelating ability in a dose-dependent manner. At the same time, it significantly inhibits the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) and the production of pro-inflammatory cytokines in RAW 264.7 cells induced by LPS through blocking the mitogen-activated protein kinase (MAPK)/nuclear factor kappa beta (NF-κB) signaling pathway. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Manipulation experiments confirm that benzoxazinoids suppress herbivore growth under iron-deficient conditions and in the presence of chelated iron but enhance herbivore growth in the presence of free iron in the growth medium. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Current treatment strategies can be roughly classified into six groups: 1) lowering ASYN expression (antisense therapy), 2) inhibition of formation of toxic ASYN aggregates (aggregation inhibitors, chelators), 3) dissolving or removal of intracellular or extracellular toxic AYSN aggregates (active and passive immunotherapy, aggregation inhibitors), 4) enhancement of cellular clearance mechanisms (autophagy, lysosomal microphagy) for removal of toxic forms of alpha-synuclein, 5) modulation of neuroinflammatory processes and 6) neuroprotective strategies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Many studies of (212)Pb-labeling of various biomolecules through bifunctional chelators have been conducted. Another approach to exploiting the cytotoxic effect is coupling the radionuclide to a microparticle acting as a carrier vehicle, which could be used for treating disseminated cancers in body cavities. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Both the kinetic analysis and docking study revealed that 17f was a mixed type AChE inhibitor. 17f was also a good antioxidant (ORAC = 3.3 eq), selective metal chelator and huMAO-B inhibitor (IC(50) = 8.8 µM). Moreover, it showed remarkable inhibition of self- and Cu(2+)-induced Aβ(1–42) aggregation with a 78.0 and 93.5% percentage rate at 25 µM, respectively, and disassembled self-induced and Cu(2+)-induced aggregation of the accumulated Aβ(1–42) fibrils with 72.3 and 84.5% disaggregation rate, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The orally bioavailable copper chelating agent tetrathiomolybdate (TM) has been associated with a significant survival benefit in high-risk triple negative breast cancer (TNBC) patients. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We demonstrated a novel, faster, and less laborious extraction method using the chelator ethylene glycol l-bis(β-aminoethyl ether)-N,N,N′,N′-tetra acetic acid (EGTA) as a stabilizing agent and synthetic quartz beads for homogenization under an argon atmosphere. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To evaluate antioxidant effects, different chemical methods (ABTS, DPPH, CUPRAC, FRAP, metal chelating and phosphomolybdenum) were applied. With regard to enzyme inhibitory properties, cholinesterases, amylase, glucosidase and tyrosinase were used. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These findings suggested that the chelate thermodynamic stability and Fe(2+) may play important roles in attenuating the effect of GBCAs on the thyroid hormone-mediated dendritogenesis of Purkinje cells in in vitro settings.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Greater antioxidant capacity in honeydew honey was proven with higher total phenolic compounds, ABTS, DPPH, superoxide radical scavenging activities, peroxyl radical inhibition, iron chelation, and ferric reducing power. Using principal component analysis (PCA), two clusters of stingless bee honey from the honeydew and blossom origin were observed. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The molecular features of the dipeptide underlie the antioxidant, anti-aggregating and metal chelating ability showed in a large number of physiological effects, while the biological mechanisms involved in the protective role found against several diseases cannot be explained on the basis of the above-mentioned properties alone, requiring further research efforts. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Inspired by the performance of h-BN based nanomaterials in expediting key organic transformations, we channelized our research efforts towards engineering the inherent surface properties of the exclusively stacked h-BN nanosheets through the incorporation of a novel competent copper complex of a bidentate chelating ligand 2-hydroxy-4-methoxybenzophenone (BP). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The effect of an iron chelator deferoxamine pretreatment on aged sepsis rats was also examined. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Taking advantage of alginate’s superior metal chelating properties, copper nanoparticle-decorated photocatalysts were developed after a pyrolytic or calcination-sintering procedure, yielding ceramic beads with enhanced photocatalytic and mechanical properties, excellent resistance to attrition, and optimized handling compared to powdered photocatalysts. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…High levels of antioxidant components and high antioxidant activities such as DPPH radical scavenging, ferrous ion chelation, and reducing power were measured in 20 mg/mL water and ethanol extracts of the white truffle fermentation products. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, we prepared PVA–CS/SA–Ca(2+) core–shell hydrogels with bilayer space by cross-linking PVA and CS to form a core structure and chelating SA and Ca(2+) to form a shell structure to achieve multiple substance loading and multifunctional expression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It is well-known that 1,3-dicarbonyl compounds such as TeA are relatively easy to deprotonate (the pK(a) of TeA is 3.5), yielding an enolate anion stabilized by resonance. The chelating and hydrogen-donor features of bim allow simultaneous binding to the metal core and to the target β-diketonate delocalized anion. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this paper, bioactive properties such as antioxidant, enzyme inhibition, and chelating power are reviewed in terms of synergism and antagonism of coffee phenolics and other bioactive compounds that are introduced into the matrix, such as cacao, ginger, cinnamon, willow bark, cardamom, and chili pepper. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso