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  1. 10561
    “…These findings offer the opportunity, e.g., by using chelating therapies, to improve mitochondrial bioenergetics in patients with idiopathic Parkinson's disease. …”
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    Relationship between brain iron deposition and mitochondrial dysfunction in idiopathic Parkinson’s disease
  2. 10562
    “…Each Ag(I) ion is coordinated by two carboxyl­ate oxygen atoms in a chelating coordination mode, as well as one of the nitro­gen atoms of two neighbouring L ligands. …”
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    Novel three-dimensional coordination polymer of 2-(1,3,5-tri­aza-7-phospho­niatri­cyclo­[3.3.1.1(3,7)]decan-7-yl)ethanoic acid with silver(I) tetra­fluoro­borate
  3. 10563
    “…The total antioxidant capacity and the metal chelating activities of CWSP at 3 mg/ml were equivalent to 116.34 µg ascorbic acid and 62.57%, respectively. …”
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    Antioxidant activities, functional properties, and application of a novel Lepidium sativum polysaccharide in the formulation of cake
  4. 10564
    “…In summary, a short stretch of nucleotides has been cloned, coding for the HEV MTase of 37 kDa, which binds Mg(2+) and modulate its activity. The chelation of magnesium reversed the changes, confirming its role in enzyme activity.…”
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    Biochemical and Biophysical Characterisation of the Hepatitis E Virus Guanine-7-Methyltransferase
  5. 10565
    “…All studied ethanolic leaf extracts exhibited significant DPPH and NO radical scavenging ability, lipid peroxidation inhibition, and reducing power, as well as moderate iron-chelating properties. Together with S. officinalis and S. fruticosa, S. verticillata showed anti-acetylcholinesterase activity, while S. glutinosa was also found to possess the ability to inhibit α-glucosidase. …”
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    Comparative Antioxidant, Anti-Acetylcholinesterase and Anti-α-Glucosidase Activities of Mediterranean Salvia Species
  6. 10566
    “…Our studies further revealed that the resting state of VP1 dimer is stabilized by a divalent ion, and chelation using EDTA increases capsid diameter, exposing new hydrophobic and antigenic sites and suggesting a transition to the rising conformation. …”
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    Atomic structure of the predominant GII.4 human norovirus capsid reveals novel stability and plasticity
  7. 10567
    por Chanpong, Atchariya, Dhawan, Anil
    Publicado 2022
    “…For WD patients treated with chelating agents, adherence to the therapy is essential for long-term success. …”
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    Wilson disease in children and young adults - State of the art
  8. 10568
    “…LaCl(3) and GdCl(3), both Ca(2+) channel blockers, at concentrations ≥ 50 μM showed complete inhibition of zoospore chemotaxis, root attachment and zoosporangia root infection. The Ca(2+) chelator EGTA, showed efficient chemotaxis inhibition but had relatively less effect on root attachment. …”
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    Subversion of Phytomyxae Cell Communication With Surrounding Environment to Control Soilborne Diseases; A Case Study of Cytosolic Ca(2+) Signal Disruption in Zoospores of Spongospora subterranea
  9. 10569
    “…Prophylactic treatment in beta-thalassemia patients with iron-chelator deprivation drugs, such as deferiprone, may help in preventing these particular fungal infections.…”
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    Disseminated Cunninghamella spp. Endocarditis in a Beta-Thalassemia Patient after Asymptomatic COVID-19 Infection
  10. 10570
    “…PCPLC enzymatic activity essentially requires Zn(2+), and D609 might act as a potential chelator of Zn(2+), thereby blocking PCPLC enzymatic activity. …”
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    Tricyclodecan-9-yl-Xanthogenate (D609): Mechanism of Action and Pharmacological Applications
  11. 10571
    “…In this work, oligonucleotide aptamers toward STX were screened based on immobilizing libraries on Immobilized Metal-Chelate (IMC), such as Ni-NTA Sepharose, and the IMC-SELEX was conducted by the G-quadruplex library and the random library, respectively. …”
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    A Novel SELEX Based on Immobilizing Libraries Enables Screening of Saxitoxin Aptamers for BLI Aptasensor Applications
  12. 10572
    “…Thiosemicarbazones work as chelating binders, reacting with metal ions. The objective of this work was to investigate the in silico, in vitro, and in vivo toxicity and oxidative stress of 2-acetylpyridine-N(4)-orthochlorophenyl thiosemicarbazone (TSC01). …”
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    Evaluation of Toxicity and Oxidative Stress of 2-Acetylpyridine-N(4)-orthochlorophenyl Thiosemicarbazone
  13. 10573
    por Leong, Stanley P.
    Publicado 2021
    “…Technetium-99m-labeled Tilmanocept or Lymphoseek® (Cardinal Health, Dublin, Ohio) is a soluble, synthetic molecule with a small diameter (7 nm), which is comprised of technetium-99m chelated to a dextran backbone containing multiple units of mannose ligands with a high affinity for CD206, a receptor located on the surface of macrophages and dendritic cells that are found in high concentration in lymph nodes. …”
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    Detection of melanoma, breast cancer and head and neck squamous cell cancer sentinel lymph nodes by Tc-99m Tilmanocept (Lymphoseek®)
  14. 10574
    “…Iron deposition and the subsequent ferroptosis has been found to be a potential mechanism underlying neuronal loss in many neurodegenerative diseases. Iron chelators, antioxidants and hepcidin were found useful for treating AD, which represents an important direction for AD treatment research and drug development in the future. …”
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    Iron Dyshomeostasis and Ferroptosis: A New Alzheimer’s Disease Hypothesis?
  15. 10575
    “…HU target these cells by matrix metallopeptidase 2 (MMP2) deficiency rather than subordinate ribonucleotide reductase regulatory subunit M2 (RRM2) inhibition, where MLL directly regulates MMP2 expression and is decreased in most MLL-r AMLs. Moreover, iron chelation of HU is also indispensable for inducing cell stress, and MMP2 is the support factor to protect cells from death. …”
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    Targeting matrix metallopeptidase 2 by hydroxyurea selectively kills acute myeloid mixed-lineage leukemia
  16. 10576
    “…We propose to exploit the properties of tannic acid, a known plant-derived antioxidant, to chelate iron ions, forming hydrophobic complexes that can be coated with a biocompatible and biodegradable phospholipid to improve stability in biological media. …”
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    Tannic Acid–Iron Complex-Based Nanoparticles as a Novel Tool against Oxidative Stress
  17. 10577
    “…Collectively, the present results will provide a basis for the design of a chelating agent (e.g., adding carboxyl or a benzene ring) to effectively remove heavy metals from the environment.…”
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    Interaction Structure and Affinity of Zwitterionic Amino Acids with Important Metal Cations (Cd(2+), Cu(2+), Fe(3+), Hg(2+), Mn(2+), Ni(2+) and Zn(2+)) in Aqueous Solution: A Theoretical Study
  18. 10578
    “…Changes in chaperones, transporters, and chelators demonstrate an initial state of copper overload in the cell that over time shifts to a state of copper deficiency. …”
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    Fatty Acid Uptake in Liver Hepatocytes Induces Relocalization and Sequestration of Intracellular Copper
  19. 10579
    “…Through the special chemical structure of dopamine (DA), superhydrophobic polyester (PET) fabric was fabricated by introducing the low surface energy substance hexadecyltrimethoxysilane (HDS) into the PET fabric and chelating Fe ions with phenolic hydroxyl groups of polydopamine (PDA) to form a rough surface. …”
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    Facile fabrication of superhydrophobic polyester fabric based on rapid oxidation polymerization of dopamine for oil–water separation
  20. 10580
    “…In this work, we describe the photoisomerization of facial rhenium(i) tricarbonyl complexes bearing P,N-bidentate pyridyl/phosphine ligands with different chelating rings and anions: RePNBr, RePNTfO, and RePNNBr, which are triggered under irradiation at 365 nm in solutions. …”
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    Photochemistry of P,N-bidentate rhenium(i) tricarbonyl complexes: reactive species generation and potential application for antibacterial photodynamic therapy
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