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  1. 10881
    “…Importantly, this modification mitigated the penalty on uPAR-affinity typically observed after conjugation to macrocyclic chelators. Cyclization did not impair tumor targeting efficiency of AE105 in vivo as assessed by PET imaging and a trend towards increased tracer uptake was observed. …”
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    Targeted imaging of uPAR expression in vivo with cyclic AE105 variants
  2. 10882
    “…The results showed that a divalent cation chelating agent (EGTA) and calcium channel inhibitors (Bepridil hydrochloride and BAPTA-acetoxymethylate) could inhibit PEDV proliferation while effectively reducing the intracellular Ca(2+) concentration. …”
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    Mechanism of Lactiplantibacillus plantarum regulating Ca(2+) affecting the replication of PEDV in small intestinal epithelial cells
  3. 10883
    “…The results underscore EPS400′s prowess in scavenging radicals, including the 2,2-diphenyl-1-picrylhydrazyl radical, 2,2′-azino-di-(3-ethylbenzthiazoline sulfonic acid) radical, superoxide radical, hydroxyl radical, and chelating activity targeting the ferrous ion. Furthermore, EPS400 displayed substantial antibacterial effectiveness against prevalent food spoilage bacteria such as Pseudomonas aeruginosa NCDC105 and Micrococcus luteus. …”
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    Multi-Faceted Bioactivity Assessment of an Exopolysaccharide from Limosilactobacillus fermentum NCDC400: Antioxidant, Antibacterial, and Immunomodulatory Proficiencies
  4. 10884
    “…RESULTS: A fully-automated manufacturing process for [(68)Ga]Ga-FAPI-46 was developed starting with the (68)Zn[p,n](68)Ga cyclotron bombardment to provide [(68)Ga]GaCl(3), automated purification of the [(68)Ga]GaCl(3), chelation with the precursor, and final formulation/purification. …”
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    Fully automated radiosynthesis of [(68)Ga]Ga-FAPI-46 with cyclotron produced gallium
  5. 10885
    “…In this study, we present the development and potential application of an iridium (iii) complex, (Cp(xbiPh)) Ir (N^N) Cl, where Cp(xbiPh) represents 1-biphenyl-2,3,4,5-tetramethyl cyclopentadienyl, and N^N denotes 2-(3-(4-nitrophenyl)-1H-1,2,4-triazol-5-yl) pyridine chelating agents, to address this challenge through a mechanism governed by the regulation of an antioxidant protein. …”
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    Iridium metal complex targeting oxidation resistance 1 protein attenuates spinal cord injury by inhibiting oxidative stress-associated reactive oxygen species
  6. 10886
    “…Ketone insertion proceeds via an associative reaction initiated by ketone coordination at the metal center, followed by the opening of the five-membered chelate ring, and finally an intramolecular nucleophilic attack of the noncoordinated phosphine arm at the carbonyl atom of the ketone. …”
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    Pyrrole-Based Ti(III) and Ti(IV) PNP Pincer Complexes: Insertion of Ketones into the Ti(IV)-Phosphorus Bond
  7. 10887
    “…Herein, two copper (Cu)(II) tropolone derivatives, [Cu(Trop)Cl] and [Cu(Trop)Sac], both containing the N,N-chelated 4,4′-bishydroxymethyl-2,2′-bipyridne ligand, were evaluated for their anticancer and anti-invasive properties. …”
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    New Copper-Based Metallodrugs with Anti-Invasive Capacity
  8. 10888
    “…Furthermore, Ca(2+) chelator, CREB inhibitor, and MAPK inhibitors dramatically blocked the up-regulation of IL-6, CXCL1, and COX2 in AJSAF-treated C2C12 cells. …”
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    Mechanism of Innate Immune Response Induced by Albizia julibrissin Saponin Active Fraction Using C2C12 Myoblasts
  9. 10889
    “…Marigolds possessed excellent free radical scavenging and metal chelation activities. Chamomile exhibited strong α-glucosidase inhibition activity, followed by Nasturtium. …”
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    Wild Edible Flowers of Western Himalayas: Nutritional Characterization, UHPLC-QTOF-IMS-Based Phytochemical Profiling, Antioxidant Properties, and In Vitro Bioaccessibility of Polyphenols
  10. 10890
    “…Our drug delivery system was designed to minimalize negative effect of Gd(3+) ions at magnetic resonance imaging and drug 5-FU on healthy cells due to their encapsulation into biocompatible silica matrix, so the Gd(3+) ions are more stable (in comparison to chelates), lower therapeutic dose of 5-FU is needed and its prolongated release from silica pores was confirmed. …”
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    Nanocomposite based on Gd(2)O(3) nanoparticles and drug 5-fluorouracil as potential theranostic nano-cargo system
  11. 10891
    “…In addition, copper chelation was observed. This activity was previously not detected in AE. …”
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    The Antioxidant and Immunomodulatory Potential of Coccoloba alnifolia Leaf Extracts
  12. 10892
    “…Literature data report on the use of copper in preclinical protocols for cancer treatment based on chemo-, photothermal-, or copper chelating-therapies. Copper nanoparticles exhibit anticancer activity via multiple routes, mainly involving the targeting of mitochondria, the modulation of oxidative stress, the induction of apoptosis and autophagy, and the modulation of immune response. …”
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    Evolving approaches in glioma treatment: harnessing the potential of copper metabolism modulation
  13. 10893
    “…In the presence of TA, the Fe-TA chelation and the reduction of TA could regulate Fe(ii) concentration and activate persulfate for continuously releasing reactive species under alkaline conditions. …”
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    Tannic acid promotes the activation of persulfate with Fe(ii) for highly efficient trichloroethylene removal
  14. 10894
    “…The glutathione oxidase (GSHOx)‐like activity of CMCO depletes glutathione (GSH), which diminishes the ability to chelate Cu ions, thereby exerting Cu toxicity and inducing cuproptosis in cancer cells. …”
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    Mild‐Photothermal Effect Induced High Efficiency Ferroptosis‐Boosted‐Cuproptosis Based on Cu(2)O@Mn(3)Cu(3)O(8) Nanozyme
  15. 10895
    “…The active sites on the surface of AgCu@MOF increased the lipophilicity to bacteria and caused the bacterial membrane to undergo lipid peroxidation, which resulted in the strong bactericidal properties of AgCu@MOF, and the antimicrobial activity of the dressing PCbM was as high as 99.9%. The chelation of silver ions in AgCu@MOF with chitosan occupied the surface functional groups of chitosan and reduced the crosslinking density of chitosan. …”
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    Bimetal–Organic Framework-Loaded PVA/Chitosan Composite Hydrogel with Interfacial Antibacterial and Adhesive Hemostatic Features for Wound Dressings
  16. 10896
    “…Fe(III) quantification is due by measuring the color intensity of the chelate formed between Fe(III) and salicylic acid at 525 nm. …”
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    Microflow injection analysis based on modular 3D platforms and colorimetric detection for Fe(III) monitoring in a wide concentration range
  17. 10897
    “…CONCLUSION: A discussion of sodium thiosulfate's dual role as a potent antioxidant and chelator of calcium is presented in order to better understand its role as an emerging novel therapy for the clinical syndrome of calciphylaxis and its complications.…”
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    Vascular ossification – calcification in metabolic syndrome, type 2 diabetes mellitus, chronic kidney disease, and calciphylaxis – calcific uremic arteriolopathy: the emerging role of sodium thiosulfate
  18. 10898
    “…Co-incubation with the metal chelator diethylenetriaminepentaacetate inhibited these losses, whilst minimal inhibition was seen with superoxide dismutase and catalase treatment. …”
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    Combustion of dried animal dung as biofuel results in the generation of highly redox active fine particulates
  19. 10899
    por Golladay, S A, Park, S H, Aust, A E
    Publicado 1997
    “…Treatment of cells with crocidolite pretreated with the iron chelator desferrioxamine B resulted in the same level of intracellular GSH depletion and efflux and the same decrease in gamma-GCS activity as treatment with unmodified crocidolite, which suggests that iron-catalyzed reactions were not responsible for the GSH depletion.…”
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    Efflux of reduced glutathione after exposure of human lung epithelial cells to crocidolite asbestos.
  20. 10900
    “…When hepatic NK cells were preincubated with the granzyme inhibitor 3,4-dichloroisocoumarin, or when extracellular Ca(2+ )was chelated by ethylene glycol-bis(β-aminoethyl ether)-N, N-tetraacetic acid, the enhanced cytolysis and apoptosis were completely inhibited. …”
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    MHC class I expression protects rat colon carcinoma cells from hepatic natural killer cell-mediated apoptosis and cytolysis, by blocking the perforin/granzyme pathway
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