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1081por Bastin, Alireza, Shiri, Hamidreza, Zanganeh, Sareh, Fooladi, Saba, Momeni Moghaddam, Mohammad Amin, Mehrabani, Mehrnaz, Nematollahi, Mohammad Hadi“…It could be concluded that the use of iron chelators to reduce iron intake can be considered a therapeutic goal. …”
Publicado 2021
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1082por Zairov, Rustem R., Dovzhenko, Alexey P., Sarkanich, Kirill A., Nizameev, Irek R., Luzhetskiy, Andrey V., Sudakova, Svetlana N., Podyachev, Sergey N., Burilov, Vladimir A., Vatsouro, Ivan M., Vomiero, Alberto, Mustafina, Asiya R.“…The report introduces hybrid polyelectrolyte-stabilized colloids combining blue and green-emitting building blocks, which are citrate carbon dots (CDs) and [TbL](+) chelate complexes with 1,3-diketonate derivatives of calix[4]arene. …”
Publicado 2021
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1083“…Copper chelating enzymatic hydrolysate was isolated by HiTrap chelating column and purified further by rpHPLC. …”
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1084por Xiong, Yu, Chen, Zi-Hong, Zhang, Feng-Li, Yu, Zhi-Ying, Liu, Bin, Zhang, Chong, Zhao, Li-Na“…The results of UV, X-ray diffraction (XRD), (1)H NMR and SEM structure analysis showed that the binding of selenium in the hydrolysate of Grifola frondosa protein was successful, and the amino and carboxyl groups of RLA were involved in the coordination of Se, which was the main site of chelation. The results of absorption of RLA-Se chelate in Caco-2 cells showed that RLA-Se chelate could be used as selenium supplement source. …”
Publicado 2021
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1085por Nazari, Mojgan, Ho, Kenneth W., Langley, Natasha, Cha, Kuan M., Kodsi, Raymond, Wang, Mawson, Laybutt, D. Ross, Cheng, Kim, Stokes, Rebecca A., Swarbrick, Michael M., Gunton, Jenny E.“…These studies identify iron chelation as a strategy to preferentially activate beige fat. …”
Publicado 2022
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1086“…This finding suggests silymarin as a safe and effective natural iron‐chelating agent for the treatment of iron‐overloaded conditions.…”
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1087por Paterson, Joy R., Beecroft, Marikka S., Mulla, Raminder S., Osman, Deenah, Reeder, Nancy L., Caserta, Justin A., Young, Tessa R., Pettigrew, Charles A., Davies, Gareth E., Williams, J. A. Gareth, Sharples, Gary J.“…These effects do not correlate with the absolute known chelant metal ion affinities in solution; however, for at least five chelators for which key data are available, they can be explained by differences in the relative affinity of chelants for each metal ion. …”
Publicado 2022
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1088por Sethuram, S., Levy, T., Foss-Feig, J., Halpern, D., Sandin, S., Siper, P. M., Walker, H., Buxbaum, J. D., Rapaport, R., Kolevzon, A.“…BACKGROUND: Phelan–McDermid syndrome (PMS) is caused by 22q13 deletions including SHANK3 or pathogenic sequence variants in SHANK3 and is among the more common rare genetic findings in autism spectrum disorder (ASD). …”
Publicado 2022
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1089por Phelan, Katy, Boccuto, Luigi, Powell, Craig M., Boeckers, Tobias M., van Ravenswaaij-Arts, Conny, Rogers, R. Curtis, Sala, Carlo, Verpelli, Chiara, Thurm, Audrey, Bennett, William E., Winrow, Christopher J., Garrison, Sheldon R., Toro, Roberto, Bourgeron, Thomas“…Phelan-McDermid syndrome (PMS) was initially called the 22q13 deletion syndrome based on its etiology as a deletion of the distal long arm of chromosome 22. …”
Publicado 2022
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1090“…INTRODUCTION: Iron chelation therapy (ICT) is essential to prevent complications of iron overload in patients with transfusion-dependent thalassaemia. …”
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1091por Selyutina, Olga Yu., Kononova, Polina A., Koshman, Vladimir E., Fedenok, Lidiya G., Polyakov, Nikolay E.“…In the present study, we have examined the influence of ascorbic acid on lipid peroxidation in a model system that mimics the cell membrane, namely micelles of linoleic acid (LA), induced by chelate complexes of iron and copper ions with quinone-chelator 2-phenyl-4-(butylamino)-naphtholquinoline-7,12-dione (Q1). …”
Publicado 2022
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1092por Xu, Yunjie, Wang, Yingwei, An, Jusung, Sedgwick, Adam C., Li, Mingle, Xie, Jianlei, Hu, Weibin, Kang, Jianlong, Sen, Sajal, Steinbrueck, Axel, Zhang, Bin, Qiao, Lijun, Wageh, Swelm, Arambula, Jonathan F., Liu, Liping, Zhang, Han, Sessler, Jonathan L., Kim, Jong Seung“…We report here a dual-therapeutic prodrug, DOXjade, that allows for iron chelation chemo-photothermal cancer therapy. This prodrug takes advantage of the clinically approved iron chelator deferasirox (ExJade®) and the topoisomerase 2 inhibitor, doxorubicin (DOX). …”
Publicado 2021
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1093“…[Image: see text] Chelating agents’ solutions were introduced as effective alternatives to strong acids to be used in acid-sensitive situations such as high temperature and salinity conditions. …”
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1094por Boccuto, Luigi, Mitz, Andrew, Abenavoli, Ludovico, Sarasua, Sara M., Bennett, William, Rogers, Curtis, DuPont, Barbara, Phelan, Katy“…Phelan–McDermid syndrome (PMS) is a multi-systemic disorder characterized by both genetic and phenotypic variability. …”
Publicado 2022
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1095por Kolevzon, A., Breen, M. S., Siper, P. M., Halpern, D., Frank, Y., Rieger, H., Weismann, J., Trelles, M. P., Lerman, B., Rapaport, R., Buxbaum, J. D.“…BACKGROUND: Phelan-McDermid syndrome (PMS) is caused by haploinsufficiency of the SHANK3 gene and is characterized by global developmental delays and autism spectrum disorder (ASD). …”
Publicado 2022
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1096“…BACKGROUND: Regular blood transfusions in thalassemia patients can lead to severe complications and iron chelation therapy is required as a treatment. Thalassemia is common in Thailand and the drugs used in iron chelation therapy are deferoxamine and deferiprone. …”
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1097por Fèvre, Jeanne, Leveille, Elena, Jeanson, Aurélie, Santucci-Darmanin, Sabine, Pierrefite-Carle, Valérie, Carle, Georges F., Den Auwer, Christophe, Di Giorgio, ChristopheEnlace del recurso
Publicado 2022
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1098“…Deferasirox is being increasingly used as an iron-chelating agent for the treatment of iron overload in both adults and children. …”
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1099por Sarkar, Subhendra, Vinokur, Zoya, Buitrago, Bleidis, Mousa, Lin, Sanchez, Hayley, Basilicata, Analia, Douglas, Jodi-Ann, Reddock, Seanetta“…Although the mechanisms are unknown, our experiments were designed to test if this toxicity can be attributed to “transmetallation” or “chelation” reactions freeing up lanthanides or chelated transition metals in acidic fruits used as phantoms representing the biologically active and mineral-rich carbohydrate matrix. …”
Publicado 2022
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1100por Serrada-Tejeda, Sergio, Martínez-Piédrola, Rosa M., Máximo-Bocanegra, Nuria, Sánchez-Herrera-Baeza, Patricia, Pérez-de-Heredia-Torres, Marta“…INTRODUCTION: The variety in symptomatology and clinical presentation of individuals diagnosed with Phelan-McDermid Syndrome (PMS) can delay medical diagnosis, so identifying specific neurobehavioral variables and facilitating differential diagnosis with patients with idiopathic Autism Spectrum Disorder (ASD) can guide early detection. …”
Publicado 2022
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