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  1. 11201
    “…Catalase and bathocuproine, a Cu(I)‐specific chelator, inhibited the DNA damage, suggesting the involvement of H(2)O(2) and Cu(I). …”
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    Oxidative DNA Damage Induced by a Metabolite of 2–Naphthylamine, a Smoking‐related Bladder Carcinogen
  2. 11202
    por Aronow, Wilbert S.
    Publicado 2017
    “…In these patients, the treatment of choice is iron chelation therapy.…”
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    Management of cardiac hemochromatosis
  3. 11203
    “…Here, we found that GDF11 induced intracellular Ca(2+) increases in neonatal rat cardiomyocytes and that this response was blocked by chelating the intracellular Ca(2+) with BAPTA-AM or by pretreatment with inhibitors of the inositol 1,4,5-trisphosphate (IP(3)) pathway. …”
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    GDF11 Modulates Ca(2+)-Dependent Smad2/3 Signaling to Prevent Cardiomyocyte Hypertrophy
  4. 11204
    “…Substituents on the chelated ligand decreased the turnover frequency in the order Nb > Tf > Ts > Ms. …”
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    Transfer Hydrogenation and Antiproliferative Activity of Tethered Half-Sandwich Organoruthenium Catalysts
  5. 11205
    “…The third Co center has an octa­hedral N(3)O(3) coordination environment that involves three pyridine ligands, and two bridging sulfate ligands with one sulfate chelating the cobalt atom.…”
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    The crystal structures of iron and cobalt pyridine (py)–sulfates, [Fe(SO(4))(py)(4)](n) and [Co(3)(SO(4))(3)(py)(11)](n)
  6. 11206
    “…These compunds were tested for metal chelating effects and to determine the phrase in which inhibition occured between two physiologically pertinent compunds and carbonic anhydrase (CA) isozymes I and II (hCA I and II), butyrylcholinesterase (BChE) and acetylcholinesterase (AChE). …”
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    Synthesis and bioactivity of several new hetaryl sulfonamides
  7. 11207
    “…If lactones coordinate to MgCl(2), the most likely binding mode is via the carbonyl oxygen. A chelating coordination cannot be ruled out and seems to gain importance upon increasing ring-size of the lactone. …”
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    The Lewis Pair Polymerization of Lactones Using Metal Halides and N-Heterocyclic Olefins: Theoretical Insights
  8. 11208
    “…Echinochrome A (EchA) is a marine bioproduct extracted from sea urchins having antioxidant, antimicrobial, anti-inflammatory, and chelating effects, and is the active component of the clinical drug histochrome. …”
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    A Novel Atypical PKC-Iota Inhibitor, Echinochrome A, Enhances Cardiomyocyte Differentiation from Mouse Embryonic Stem Cells
  9. 11209
    por Maragos, Chris M.
    Publicado 2018
    “…The potential for CPA to act as a chelator also has implications for methods to detect this toxin. …”
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    Complexation of the Mycotoxin Cyclopiazonic Acid with Lanthanides Yields Luminescent Products
  10. 11210
    “…First, the antioxidant system maintaining ROS homeostasis and osmotic adjustment is excited to maintain stability of cell osmotic potential. Cd is chelated into its stable form to reduce its toxicity. …”
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    Physiological and biochemical analysis of mechanisms underlying cadmium tolerance and accumulation in turnip
  11. 11211
    “…Speciation analysis using synchrotron-based X-ray absorption near-edge structure (XANES) showed that ZnEDTA was in fact taken up in chelated form and not as ionic Zn (Zn(2+)). The XANES data also showed that Zn, from both treatments, was then complexed by ligands in the leaf (e.g. phytate and citrate), potentially in response to localized Zn toxicity. …”
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    Foliar application of zinc sulphate and zinc EDTA to wheat leaves: differences in mobility, distribution, and speciation
  12. 11212
    “…The results demonstrated salinomycin to be a better potential chelating agent for treatment of Cd-induced brain injury compared to DMSA and monensin.…”
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    Comparative effects of meso-2,3- dimercaptosuccinic acid, monensin, and salinomycin on cadmium-induced brain dysfunction in cadmium-intoxicated mice
  13. 11213
    “…Importantly, this may also have relevance for therapeutic directions, and indeed, the use of iron chelators such as deferiprone and deferoxamine have been reported to alleviate the phenotypes, reduce phosphorylated tau levels and stabilize iron regulation in various animal models. …”
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    Untangling Tau and Iron: Exploring the Interaction Between Iron and Tau in Neurodegeneration
  14. 11214
    “…Moreover, increased tension at AJs was indicated by immunostaining with a conformation-sensitive antibody targeting the α18-subunit of α-catenin. Ca(2+) chelation by BAPTA-AM and ROCK1 inhibition by Y27632 abolished both increase of tension along AJs as well as barrier dysfunction. …”
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    Histamine causes endothelial barrier disruption via Ca(2+)-mediated RhoA activation and tension at adherens junctions
  15. 11215
    por Park, Ga-Bin, Jin, Dong-Hoon, Kim, Daejin
    Publicado 2018
    “…Targeted inhibition of p53 activity or ER stress or treatment with the Ca(2+)-chelating agent BAPTA-AM suppressed the ER stress-mediated Ca(2+) release and apoptosis. …”
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    Sequential treatment with celecoxib and bortezomib enhances the ER stress-mediated autophagy-associated cell death of colon cancer cells
  16. 11216
    “…Its r1 relaxation rate was 10.515 mM(−1) s(−1), much higher than that of other Gd chelates in clinical use. The probe showed no cytotoxicity at the tested concentrations in vitro, and its ability to target A549 cells and SUNE-1-5-8F cells was preliminarily evaluated through in vitro fluorescence imaging and MR imaging. …”
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    Synthesis and In Vitro Study of a Dual-Mode Probe Targeting Integrin α(v)β(3)
  17. 11217
    “…The main potential market segments identified (from a financial perspective) include composite nanofillers, solid foams, emulsion stabilizers, chelating agents, and UV protection. Our technical, financial, and market assessment represent the basis for R&D planning and efforts to lower the risk related to expected industrialization efforts. …”
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    Techno-Economic Assessment, Scalability, and Applications of Aerosol Lignin Micro- and Nanoparticles
  18. 11218
    “…Also, the observed selectivity in the case of ortho-methoxyphenylboronic acid suggested an additional metal O-chelation effect in the transition state, apparently not present in the ortho-chloro analogues. …”
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    Some mechanistic aspects regarding the Suzuki–Miyaura reaction between selected ortho-substituted phenylboronic acids and 3,4,5-tribromo-2,6-dimethylpyridine
  19. 11219
    “…A highly selective fluorescent sensor H(4)L based on a bis(salamo)-type compound with two N(2)O(2) chelating moieties as ionophore was successfully developed. …”
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    Exploration and application of a highly sensitive bis(salamo)-based fluorescent sensor for B(4)O(7)(2−) in water-containing systems and living cells
  20. 11220
    “…Herein, the coordination chemistry of chelating ligands with a diphosphine imine framework (PCNP) to nickel is investigated. …”
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    Versatile Coordination and C–C Coupling of Diphosphine-Tethered Imine Ligands with Ni(II) and Ni(0)
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