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  1. 11281
    “…CONCLUSION: The results justify that the chelation of metals with Schiff base ligands enhances their biological activities against drug-resistant microbial strains.…”
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    Biological investigation of novel metal complexes of 2-amino-4-substituted phenylthiazole Schiff bases
  2. 11282
    “…Here, we report that in 1-methyl-4-phenylpyridinium (MPP(+))-induced culture models of PD, the buffering of cytosolic Ca(2+) by calbindin-D28 overexpression or treatment with a chemical Ca(2+) chelator reversed impaired autophagic flux, protecting cells against MPP(+)-mediated neurotoxicity. …”
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    Buffering of cytosolic calcium plays a neuroprotective role by preserving the autophagy-lysosome pathway during MPP(+)-induced neuronal death
  3. 11283
    “…The central idea is the modification of magnetic NPs using Rubia tinctorum extract, which consists of numerous carbonyl and phenolic hydroxyl functional groups to increase adsorption of metals and chelate silver ions, and decrease the adsorption of silver ions by Ag NPs, in situ. …”
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    In Situ Immobilized Silver Nanoparticles on Rubia tinctorum Extract-Coated Ultrasmall Iron Oxide Nanoparticles: An Efficient Nanocatalyst with Magnetic Recyclability for Synthesis of Propargylamines by A(3) Coupling Reaction
  4. 11284
    “…This effect was preserved in the presence of BAPTA (10 and 20 µM) which chelated the intracellular calcium, but eliminated after withdrawal of extracellular calcium, application of 2-aminoethoxy-diphenylborane (75 µM) to inhibit store-operated calcium channel or thapsigargin (2 µM) to delete calcium store. …”
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    Docosahexaenoic acid reduces adenosine triphosphate-induced calcium influx via inhibition of store-operated calcium channels and enhances baseline endothelial nitric oxide synthase phosphorylation in human endothelial cells
  5. 11285
    “…Also, previous studies have reported that EGCG can chelate many divalent metal ions. What we investigate here is whether EGCG can interfere with the Cu(II) induced fibrillation of α-Syn and protect the cell viability. …”
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    Complex of EGCG with Cu(II) Suppresses Amyloid Aggregation and Cu(II)-Induced Cytotoxicity of α-Synuclein
  6. 11286
    “…After AP activity was eliminated by using EDTA to chelate metal ions, the enzymatic activity could be recovered by the supplementation of Ca(2+), Mg(2+) and Mn(2+) in all cases but not by that of Zn(2+). …”
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    Non-Conventional Metal Ion Cofactor Requirement of Dinoflagellate Alkaline Phosphatase and Translational Regulation by Phosphorus Limitation
  7. 11287
    por Karponi, Garyfalia, Zogas, Nikolaos
    Publicado 2019
    “…Nowadays, clinical trials being held on a worldwide setting, have demonstrated that, by re-establishing effective hemoglobin production, patients may be rendered transfusion- and chelation-independent and evade the immunological complications that normally accompany allogeneic hematopoietic stem cell transplantation. …”
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    Gene Therapy For Beta-Thalassemia: Updated Perspectives
  8. 11288
    “…The PELS showed 31.79% metal chelating capacity and 87.79% inhibition of linoleic acid auto‐oxidation at 1.6 mg/ml. …”
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    Polyphenols extract from lotus seedpod (Nelumbo nucifera Gaertn.): Phenolic compositions, antioxidant, and antiproliferative activities
  9. 11289
    “…Siderophores are low molecular weight iron chelators that bind to iron and are actively transported inside the cell through specific binding protein complexes. …”
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    Present and future of siderophore-based therapeutic and diagnostic approaches in infectious diseases
  10. 11290
    “…Siderophores, which are secondary metabolites, function as natural chelators (e.g., iron). They are produced and secreted by many bacteria and have been experimented on as “carriers” of several types of antibiotics that pass the cell membrane of challenging Gram negative bacteria. …”
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    Delftibactin-A, a Non-ribosomal Peptide With Broad Antimicrobial Activity
  11. 11291
    “…Despite the fact that the di­phenyl­acetate ligand is sterically bulky, this does not inter­fere with the formation of the described aqua-bridged dimeric core, even with a 2,2′-bi­pyridine ligand, which has a strong chelating effect.…”
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    Crystal structures of two dimeric nickel di­phenyl­acetate com­plexes
  12. 11292
    “…Furthermore, each six-membered chelate ring adopts an envelope conformation with the Cu atom being the flap. …”
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    Bis[2-(4,5-diphenyl-1H-imidazol-2-yl)-4-nitrophenolato]copper(II) dihydrate: crystal structure and Hirshfeld surface analysis
  13. 11293
    “…The suppression of copper-induced ROS generation by the ROS scavenger N-acetyl cysteine verified copper’s functional role, while the suppression of copper’s effects by the copper chelator disulfiram, confirmed its specificity. Selective induction of HIF-1α, p53, and phosphorylated ERK proteins by copper was blocked by the knockdown of the transcription factor DEC1, suggesting copper’s effects are mediated by DEC1. …”
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    The Mechanisms Underlying the Cytotoxic Effects of Copper Via Differentiated Embryonic Chondrocyte Gene 1
  14. 11294
    “…From the mechanistic point of view, the formation of highly stable five-membered chelate by the products of l-LA ring-opening and high donor properties of phosphates are the key factors that rule the reactions. …”
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    DFT Visualization and Experimental Evidence of BHT-Mg-Catalyzed Copolymerization of Lactides, Lactones and Ethylene Phosphates
  15. 11295
    “…The latter was essential for REE‐dependent growth on methanol indicating chelator‐assisted uptake of REEs.…”
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    Use of rare‐earth elements in the phyllosphere colonizer Methylobacterium extorquens PA1
  16. 11296
    por Jensen, Jessica M., Yip, Wai Tak
    Publicado 2019
    “…Films proved to be reusable, using ethylenediaminetetraacetic acid to chelate copper and regenerate the films, with only a 6% reduction in the amount of copper(II) ions sequestered by the third use. …”
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    Amine Functionalization of Silica Sol–Gel Thin Films via Kinetic Doping: A Novel, Green Approach
  17. 11297
    “…The His(6)-tagged Mae was obtained by heterologous expression in Escherichia coli BL21 (DE3) and purified by affinity metal chelating chromatography. As determined by gel filtration and non-denaturating gradient gel electrophoresis, the molecular mass of the native enzyme is 260 kDa. …”
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    Role of the malic enzyme in metabolism of the halotolerant methanotroph Methylotuvimicrobium alcaliphilum 20Z
  18. 11298
    “…Other residues involved in hydrogen bonding are Cys65, His67, Asp64, Asp116 and chelation with Mg(2+) ion was seen for certain analogues. …”
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    Molecular docking study of lamellarin analogues and identification of potential inhibitors of HIV-1 integrase strand transfer complex by virtual screening
  19. 11299
    “…The immune protein calprotectin (CP) is released into the gut lumen during CDI to chelate zinc (Zn) and other essential nutrient metals. …”
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    The Immune Protein Calprotectin Impacts Clostridioides difficile Metabolism through Zinc Limitation
  20. 11300
    “…These effects resulted from its chelation and antioxidant, anti-inflammatory, and antiapoptotic activities. …”
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    Ziziphus spina-christi Leaf Extract Suppressed Mercury Chloride-Induced Nephrotoxicity via Nrf2-Antioxidant Pathway Activation and Inhibition of Inflammatory and Apoptotic Signaling
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