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11561por Bekkai, Douaa, Oulad El Majdoub, Yassine, Bekkai, Hamid, Cacciola, Francesco, Miceli, Natalizia, Taviano, Maria Fernanda, Cavò, Emilia, Errabii, Tomader, Laganà Vinci, Roberto, Mondello, Luigi, L’Bachir El Kbiach, Mohammed“…The antioxidant activity of all extracts was investigated by three different in vitro methods, namely DPPH, reducing power, and Fe(2+) chelating assays; E. scoparia aerial part extract was the most active, with an IC(50) of 0.142 ± 0.014 mg/mL (DPPH test) and 1.898 ± 0.056 ASE/mL (reducing power assay). …”
Publicado 2022
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11562por Kim, Se-Myung, Kim, Tae-Kyung, Kang, Min-Cheol, Cha, Ji Yoon, Yong, Hae In, Choi, Yun-Sang“…LE is a phenolic compound, whose 1,1-diphenyl-2-picrylhydarzyl radical scavenging activity and metal chelating activity were found to be higher than AA. …”
Publicado 2022
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11563por Zheng, Huaping, Gu, Linna, Zhao, Fulei, Zhang, Chen, Wang, Zhen, Zhou, Hong, Hu, Zhonglan, Wei, Xiaoqiong, Liu, Xiao, Luo, Feng, Zeng, Fanlian, Zhao, Qixiang, Hao, Yan, Hu, Yawen, Wang, Xiaoyan, Hu, Jing, Yu, Jiadong, Wu, Wenling, Zhou, Yifan, Zhou, Pei, Yue, Chengcheng, Huang, Nongyu, Cui, Kaijun, Li, Wei, Li, Jiong“…Notably, we demonstrated that SerpinB7 deficiency prevented the increase in intracellular Ca(2+) influx, which was partly eliminated by the intracellular Ca(2+) chelator BAPTA-AM. Our findings first described the critical role of SerpinB7 in the regulation of keratinocyte differentiation and psoriatic microenvironment mediated via keratinocytes' intracellular calcium flux, proposing a new candidate for therapeutic targets in psoriasis.…”
Publicado 2022
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11564“…This study aimed to investigate the effects of cefotaxime and cefotaxime metal complexes on oxidative stress using antioxidant assays including DPPH, ORAC, FARAB, and ABTS, a metal chelation assay, as well as the inhibition of the viability of cancer cells (HepG-2). …”
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11565por Vilhelmova-Ilieva, Neli, Petrova, Zdravka, Georgieva, Almira, Tzvetanova, Elina, Trepechova, Madlena, Mileva, Milka“…We determined their iron-reducing, copper-reducing, and metal-chelating antioxidant powers. Results: Most of the extracts tested suppress the extracellular virions of HCov. …”
Publicado 2022
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11566“…Cyclotron‐produced copper‐64 radioisotope tracers offer the possibility to perform both diagnostic investigation by positron emission tomography (PET) and radiotherapy by a theranostic approach with bifunctional chelators. The versatile chemical properties of copper add to the importance of this isotope in medicinal investigation. [(64)Cu][Cu (ATSM)] has shown to be a viable candidate for imaging of tumor hypoxia; a critical tumor microenvironment characteristic that typically signifies tumor progression and resistance to chemo‐radiotherapy. …”
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11567“…OBJECTIVE: Phytate, an important component of plant origin foods, works as a chelator for mineral nutrients such as iron. Estimating the phytate‐iron molar ratio is a traditional method to assess the bioavailability of dietary iron, and a ratio >1 is suggestive of poor absorption of iron through the intestinal mucosa. …”
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11568por Rebey, Iness Bettaieb, Bourgou, Soumaya, Rahali, Fatma Zohra, Msaada, Kamel, Ksouri, Riadh, Marzouk, Brahim“…Moreover, antioxidant activities of the extracts were determined by four different test systems, namely 2,2-diphenyl-1-picrylhydrazyl, β-carotene/linoleic acid chelating, and reducing power assays. The highest antioxidant activities were reveled in severe stressed plants. …”
Publicado 2016
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11569“…While one of the two tetrahedral voids formed from these trimeric units is filled by one bidentate, chelating μ(2)-selenate ion, the other one remains unoccupied as the corresponding second selenate ion only acts as a monodentate, μ(1)-ligand. …”
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11570por Li, Yingying, Xiao, Luyao, Tian, Juanjuan, Wang, Xiaomeng, Zhang, Xueliang, Fang, Yong, Li, Wei“…In addition, the EPS-1 exhibited certain scavenging activity on the ABTS radical and chelating activity on metal ions at relatively high concentrations. …”
Publicado 2022
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11571por Soler-Agesta, Ruth, Guerrero-Ochoa, Patricia, Marco-Brualla, Joaquín, Ibáñez-Pérez, Raquel, Marzo, Isabel, Martínez-Lostao, Luis, Anel, Alberto“…In the present work, we developed lipid nanoparticles whose surfaces can bind recombinant granulysin through the formation of a complex of coordination between the histidine tail of the protein and Ni(2+) provided by a chelating lipid in the liposome composition and termed them LUV-GRNLY, for granulysin-bound large unilamellar vesicles. …”
Publicado 2022
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11572“…PAMs collected from five 6-week-old pigs were treated with a basal media, iron chelator, or ferric ammonium citrate to maintain iron replete or induce iron deficiency or overload, respectively. …”
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11573por Tziotzi, Thomais G., Mavromagoulos, Athanasios, Murrie, Mark, Dalgarno, Scott J., Evangelisti, Marco, Brechin, Euan K., Milios, Constantinos J.“…Subsequent self-assembly is dependent on the anion of the Mn salt and the identity of the organic coligand employed—the terminally bonded imidazole and the chelating/bridging amino acid. The {Mn(3)} triangles fold up on themselves in 1, forming a wheel. …”
Publicado 2022
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11574“…[Image: see text] The synthesis, structure, photophysical properties, and electrochemistry of the first series of Pt(IV) tris-chelates bearing cyclometalated aryl-NHC ligands are reported. …”
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11575por Martineau-Côté, Delphine, Achouri, Allaoua, Wanasundara, Janitha, Karboune, Salwa, L’Hocine, Lamia“…In the oxygen radical absorbance capacity (ORAC) and the iron chelating assays, the faba beans had a lower antioxidant activity than soy. …”
Publicado 2022
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11576por Yi, Jae Kyo, Xu, Ruijuan, Obeid, Lina M., Hannun, Yusuf A., Airola, Michael V., Mao, Cungui“…Consistent with this notion, ACER3 was specifically inhibited by trichostatin A, a strong zinc chelator.…”
Publicado 2022
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11577por Capulín Flores, Liliana, Paul, Lucas A., Siewert, Inke, Havenith, Remco, Zúñiga-Villarreal, Noé, Otten, Edwin“…The formazan ligand coordinates the metal center in the ‘open’ form, generating a five-membered chelate ring with a pendant NH arm. The electronic absorption and emission properties of these complexes are governed by the presence of low-lying π*-orbitals on the ligand as shown by DFT calculations. …”
Publicado 2022
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11578“…Treatment consists of chelating agents, but side effects are common. We describe a patient who developed colitis during trientine treatment leading to decompensation of liver cirrhosis. …”
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11579“…Emerging evidence has revealed that ferroptosis plays an essential role in the development of diverse cardiovascular diseases (CVDs), such as hemochromatosis-associated cardiomyopathy, doxorubicin-induced cardiotoxicity, ischemia/reperfusion (I/R) injury, heart failure (HF), atherosclerosis, and COVID-19–related arrhythmias. Iron chelators, antioxidants, ferroptosis inhibitors, and genetic manipulations may alleviate the aforementioned CVDs by blocking ferroptosis pathways. …”
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11580“…The antioxidant activities were evaluated by DPPH, hydroxyl radicals scavenging, Fe(2+) chelating, and inhibition of the β-carotene oxidation abilities. …”
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