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  1. 11861
    “…In this study, a new biodegradable macromolecular contrast agent, nanoglobule-G4-cystamine-(Gd-DO3A), was prepared by conjugating Gd-DO3A chelates on the surface of a generation 4 nanoglobule, poly-l-lysine octa(3-aminopropyl)silsesquioxane dendrimer, via a disulfide spacer, where the carrier had a precisely defined nanosize that is far smaller than the renal filtration threshold. …”
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    Synthesis and evaluation of nanoglobule-cystamine-(Gd-DO3A), a biodegradable nanosized magnetic resonance contrast agent for dynamic contrast-enhanced magnetic resonance urography
  2. 11862
    “…The ligand acts as a typical bidentate chelating ligand through one of its 2-pyridyl-2H-tetra­zole units, forming a five-membered Zn—N—C—C—N metallacycle with a small N—Zn—N bite angle [77.40 (8)°]. …”
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    trans-Diaqua­bis{1,3-bis­[5-(2-pyrid­yl)-2H-tetra­zol-2-yl]propane}zinc(II) bis­(perchlorate)
  3. 11863
    “…The two bridging FB anions, one chelating FB anion and one nicotinamide (NA) ligand coordinate to one Zn cation with a distorted square-pyramidal geometry, while the two bridging FB anions, one monodentate FB anion and one NA ligand coordinate to the other Zn cation with a distorted tetra­hedral geometry. …”
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    Bis(μ-2-fluoro­benzoato-1:2κ(2) O:O′)(2-fluoro­benzoato-1κ(2) O,O′)(2-fluoro­benzoato-2κO)dinicotinamide-1κN (1),2κN (1)-dizinc(II)–2-fluoro­benzoic acid (1/1)
  4. 11864
    “…More specifically, Zn(2+) was found to block the initiation step of EAV RNA synthesis, whereas in the case of the SARS-CoV RdRp elongation was inhibited and template binding reduced. By chelating Zn(2+) with MgEDTA, the inhibitory effect of the divalent cation could be reversed, which provides a novel experimental tool for in vitro studies of the molecular details of nidovirus replication and transcription.…”
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    Zn(2+) Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture
  5. 11865
    “…These NPs significantly increase the size of aggregated mucin by approximately 30 times within 24 hrs. EGTA chelation of indigenous mucin crosslinkers (Ca(2+) ions) was unable to effectively disperse NP-induced aggregated mucins. …”
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    Functionalized Positive Nanoparticles Reduce Mucin Swelling and Dispersion
  6. 11866
    “…AGM-induced ASIC3 channel activation was not through the chelation of extracellular Ca(2+ )as occurs with increased lactate, but rather through a direct interaction with the newly identified nonproton ligand sensing domain. …”
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    ASIC3 Channels Integrate Agmatine and Multiple Inflammatory Signals through the Nonproton Ligand Sensing Domain
  7. 11867
    por Gupta, Deepika, Gupta, Rajinder K
    Publicado 2011
    “…The antioxidant activities of the extracts were assessed using DPPH and ABTS radical scavenging, FRAP, metal chelating and reducing power assays. Total phenolics, flavonoids and flavonols of extracts were also estimated using the standard methods. …”
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    Bioprotective properties of Dragon's blood resin: In vitro evaluation of antioxidant activity and antimicrobial activity
  8. 11868
    “…Two of its six phospho­nate O atoms chelate to a Mg(2+) cation in a bidentate fashion, while a third O atom bridges to a neighbouring Mg(2+) ion. …”
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    Poly[bis­[μ(2)-(dimethyl­aza­nium­yl)methyl­enediphospho­nato]magnesium]
  9. 11869
    por Tan, Mingqian, Lu, Zheng-Rong
    Publicado 2011
    “…By using proper delivery systems for loading sufficient Gd(III) chelates or superparamagnetic nanoparticles, effective molecular imaging of integrins with MRI has been demonstrated in animal models.…”
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    Integrin Targeted MR Imaging
  10. 11870
    por Grenier, Daniel, Tanabe, Shin-ichi
    Publicado 2011
    “…DESIGN: Growth studies were performed in broth media pretreated with an iron-chelating resin and supplemented with various iron sources. …”
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    Transferrin as a source of iron for Campylobacter rectus
  11. 11871
    por Dai, Min, Shi, Xiaorui
    Publicado 2011
    “…Elevation of Ca(2+) in fibrocytes, induced by photolytic uncaging of the divalent ion chelator o-nitrophenyl EGTA, results in propagation of a Ca(2+) signal to neighboring vascular cells and vasodilation in capillaries. …”
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    Fibro-Vascular Coupling in the Control of Cochlear Blood Flow
  12. 11872
    “…This hypothesis is based on several studies that may be technically problematic; including the use of BAPTA chelators, BAPTA-based fluorescent sensors, and cytotoxic concentrations of metal. …”
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    Cadmium Induces Transcription Independently of Intracellular Calcium Mobilization
  13. 11873
    “…Recent animal and human studies have suggested that the cuprizone (CPZ, a copper chelator)-fed C57BL/6 mouse may be used as an animal model of schizophrenia. …”
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    Recovery of Behavioral Changes and Compromised White Matter in C57BL/6 Mice Exposed to Cuprizone: Effects of Antipsychotic Drugs
  14. 11874
    “…The effect of the pharmacological inhibition of the ryanodine receptor (RyR), inositol 1,4,5-trisphosphate receptor (IP(3)R), and endoplasmic-reticulum Ca(2+)-ATPase (SERCA), as well as the intracellular Ca(2+)-chelator BAPTA-AM was explored on the 24-h rhythmicity of the liver-clock protein PER1 in an experimental model of circadian synchronization by light and restricted-feeding schedules. …”
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    Chronic inhibition of endoplasmic reticulum calcium-release channels and calcium-ATPase lengthens the period of hepatic clock gene Per1
  15. 11875
    por Mulcahy, Heidi, Lewenza, Shawn
    Publicado 2011
    “…Here we show that exogenous DNA and EDTA, through their ability to chelate Mg(2+), promoted biofilm formation. The repression of retS in low Mg(2+) was directly controlled by PhoPQ. …”
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    Magnesium Limitation Is an Environmental Trigger of the Pseudomonas aeruginosa Biofilm Lifestyle
  16. 11876
    “…The plant has a very effective antioxidant profile showing 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, lipoxygenase inhibition, phospholipid peroxidation inhibition, iron chelating activity, hydroxyl radical scavenging activity, superoxide dismutation, glutathione reduction and antilipid peroxidation due to its high total phenolic content with the presence of constituents like pyrogallol, caffeic acid, glycitin, etc. …”
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    Pharmacological screening of Coriandrum sativum Linn. for hepatoprotective activity
  17. 11877
    “…Lipid-based nanoparticles (NPs) with a small amount of surface-chelated nickel (Ni-NPs) were developed to easily formulate the human immunodeficiency virus (HIV) his-tagged Tat (his-Tat) protein, as well as to formulate and co-deliver two HIV antigens (his-p24 and his-Nef) on one particle. …”
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    Lipid nanoparticles with accessible nickel as a vaccine delivery system for single and multiple his-tagged HIV antigens
  18. 11878
    “…In one fumarate dianion, two carboxyl­ate groups are chelating with two Pr(3+) cations, and the other two O atoms each coordinate a Pr(3+) cation. …”
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    Poly[diaquabis­(μ(4)-fumarato-κ(4) O (1):O (1′):O (4):O (4′))(μ(4)-fumarato-κ(6) O (1):O (1),O (1′):O (4):O (4),O (4′))(μ(2)-fumaric acid-κ(2) O (1):O (4))dipraseodymium(III)]
  19. 11879
    “…Following 1-yr deferasirox therapy in the ESCALATOR study, 57% of previously chelated patients with β-thalassaemia achieved treatment success (maintenance of or reduction in liver iron concentration (LIC) vs. baseline LIC). …”
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    Importance of optimal dosing ≥30 mg/kg/d during deferasirox treatment: 2.7-yr follow-up from the ESCALATOR study in patients with β-thalassaemia
  20. 11880
    “…Pharmacological block of GABA(A) receptors and of the Na(+)-K(+)-Cl(−) cotransporters, and chelating intracellular Ca(2+), all significantly reduced the motility rate in vivo. …”
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    GABA Regulates the Multidirectional Tangential Migration of GABAergic Interneurons in Living Neonatal Mice
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