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  1. 12221
    “…CONCLUSION: Although none of the children needed chelation therapy, strategies should be developed to prevent children from being exposed to opium and other materials impregnated with lead regarding its effects on all organs of children.…”
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    Blood Lead Levels in Opium-Poisoned Children: One Cross-Sectional Study in Iran
  2. 12222
    “…Furthermore, ZnSO(4) prevented the hyperpermeability induced by zinc chelator TPEN in 2.5D culture. ZnSO(4) and TPEN induced cellular metabolism in 2D culture. …”
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    Increase in Epithelial Permeability and Cell Metabolism by High Mobility Group Box 1, Inflammatory Cytokines and TPEN in Caco-2 Cells as a Novel Model of Inflammatory Bowel Disease
  3. 12223
    “…The ethanolic extract was characterized in terms of terpenes (6.00 mg/mL), cannabidiol (4.99% w/w), phenolic compounds (1.80 mg gallic acid equivalents (GAE)/mL), antiradical, and metal ion-chelating activities (50% effective concentration (EC(50)) of 2.47 mg/mL and 0.39 mg/mL, respectively). …”
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    Antioxidant Effects of Hemp (Cannabis sativa L.) Inflorescence Extract in Stripped Linseed Oil
  4. 12224
    “…Therefore, we synthesized a series of novel derivatives to investigate the influence of the electron-donating properties of methyl substituents at the metal-chelating moiety of the EGFR inhibitor and/or the ancillary acetylacetonate (acac) ligand. …”
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    Improving the Stability of EGFR Inhibitor Cobalt(III) Prodrugs
  5. 12225
    “…This method, called the protein probe technique, is based on a peptide conjugated with Eu(3+) chelate, and it has already been applied to monitor protein structural changes and small molecule interactions at elevated temperatures. …”
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    Nanomolar Protein–Protein Interaction Monitoring with a Label-Free Protein-Probe Technique
  6. 12226
    “…Radiolabeling with macrocyclic chelators DOTA and macropa achieved full incorporation, with respective apparent (133)La molar activites of 33 ± 5 GBq/µmol and 30 ± 4 GBq/µmol. …”
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    High yield cyclotron production of a novel (133/135)La theranostic pair for nuclear medicine
  7. 12227
    “…Here, by using a toxic demyelination model, induced by cuprizone (CPZ), we investigated the protective effect of DNC on oligodendroglial lineage cells (OLLC) and myelin preservation in context of acute demyelination. CPZ is a copper chelator, thus its intake reduces the mitochondrial activity, activates oxidative stress response, leading to specific OLs death, due to their high-energy consumption. …”
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    Protective Effects of a Nano-Formulation of Curcumin against Cuprizone-Induced Demyelination in the Mouse Corpus Callosum
  8. 12228
    “…The total phenolic content, reducing capacity, iron (II) ion-chelation, and intracellular reactive oxygen species (ROS)-scavenging capacities were also investigated. …”
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    Phoenix dactylifera L. Seed Extract Exhibits Antioxidant Effects and Attenuates Melanogenesis in B16F10 Murine Melanoma Cells by Downregulating PKA Signaling
  9. 12229
    “…Metacercariae of S. falcatus and P. cambodiensis were detected only from the mullet, Chelon macrolepis. Metacercariae of Procerovum sp. were found in Channa striata and Anabas testudineus. …”
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    Larval Gnathostomes and Zoonotic Trematode Metacercariae in Fish from a Local Market in Yangon City, Myanmar
  10. 12230
    “…In this work, a halogenated and anionic Schiff-base ligand (L(2–)) is utilized as it is predisposed to chelate within a cluster core to both 3d and 4f metal ions, in different binding configurations (H(2)L = 4-chloro-2-(2-hydroxy-3-methoxybenzyliden amino)phenol). …”
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    Formation of Defect-Dicubane-Type Ni(II)(2)Ln(III)(2) (Ln = Tb, Er) Clusters: Crystal Structures and Modeling of the Magnetic Properties
  11. 12231
    “…Expressions of gene coding metal chelators were also investigated. Pdpcs1 and Pdmt3 exhibited a strong induction in plants exposed to Cr. …”
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    In-Site and Ex-Site Date Palm Exposure to Heavy Metals Involved Infra-Individual Biomarkers Upregulation
  12. 12232
    “…A number of biomarkers have shown promising results, including from tumour (programmed cell death ligand 1 (PD-L1), tumour mutational burden (TMB), stimulator of interferon genes (STING) and apoptosis-associated speck-like protein containing a CARD (ASC)), from blood (peripheral blood mononuclear cells (PBMCs), circulating tumour DNA (ctDNA), exosomes, cytokines and metal chelators) and finally the microbiome.…”
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    The Multiple Potential Biomarkers for Predicting Immunotherapy Response—Finding the Needle in the Haystack
  13. 12233
    “…To achieve this, we tested multiple regeneration conditions that can disrupt the NTA chelate on a surface fully saturated with His(6)-tagged antibody fragments (scFv-33H1F7) over ten regeneration cycles. …”
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    Novel Regeneration Approach for Creating Reusable FO-SPR Probes with NTA Surface Chemistry
  14. 12234
    “…TEM-1 specific tumor uptake was observed together with a non-saturation dependent liver uptake that could be related to the number of dodecane tetraacetic acid (DOTA) chelator per 1C1m-Fc. The objective of this study was to verify this hypothesis and to find the best DOTA per 1C1m-Fc ratio for theranostic applications. 1C1m-Fc was conjugated with six concentrations of DOTA. …”
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    Impact of DOTA Conjugation on Pharmacokinetics and Immunoreactivity of [(177)Lu]Lu-1C1m-Fc, an Anti TEM-1 Fusion Protein Antibody in a TEM-1 Positive Tumor Mouse Model
  15. 12235
    “…Finally, Meg exhibited Ca(2+)-chelating activity in olive pollen grains, which allowed the biostimulant to exert this beneficial effect also by antagonizing the undesirable effects of hydrogen peroxide on Ca(2+) metabolism.…”
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    Effects of Megafol on the Olive Cultivar ‘Arbequina’ Grown Under Severe Saline Stress in Terms of Physiological Traits, Oxidative Stress, Antioxidant Defenses, and Cytosolic Ca(2+)
  16. 12236
    “…Meso-2,3-dimercaptosuccinic acid (DMSA) is one of the efficient chelating reagents for treating the toxicity of several heavy metals. …”
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    Synthesis, structural characterization, computational studies and stability evaluations of metal ions and ZnONPs complexes with dimercaptosuccinic acid
  17. 12237
    “…On these bases, the antioxidant and iron chelator molecule, dexrazoxane, currently represents the unique FDA-approved cardioprotectant for patients treated with anthracyclines. …”
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    Metabolic Aspects of Anthracycline Cardiotoxicity
  18. 12238
    “…Carnosine is a naturally occurring dipeptide (β-alanine-L-histidine) which supports physiological homeostasis by buffering intracellular pH, chelating metals, and conjugating with and neutralizing toxic aldehydes such as acrolein. …”
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    Urinary Levels of the Acrolein Conjugates of Carnosine Are Associated with Cardiovascular Disease Risk
  19. 12239
    “…With an average number of 1.9 chelators coupled to each antibody, we achieved a two-order of magnitude increase in radiolabeling efficiency compared to literature reports. …”
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    Copper-67 radioimmunotheranostics for simultaneous immunotherapy and immuno-SPECT
  20. 12240
    “…Here, we investigated the direct involvement of EC SVMPs in observed pathological symptoms in a preclinical setup using specific Zn(++) metal chelator, Tetraethyl thiuram disulfide (TTD)/disulfiram. …”
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    Echis carinatus snake venom metalloprotease-induced toxicities in mice: Therapeutic intervention by a repurposed drug, Tetraethyl thiuram disulfide (Disulfiram)
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