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12621por Páez, David Fernando Cubides, Villalba, Xavier Guimerà, Zabalo, Nerea Abasolo, Galceran, Helena Torrell, Güell, Irene Jubany, Noguera, Xavier Gamisans“…Therefore, the abatement of NO emissions might be improved by adding a chelating agent or a mass transfer vector (MTV) to increase the solubility of this pollutant into the aqueous phase where the bioprocess takes place. …”
Publicado 2023
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12622por Fedorov, Nikolay, Zhigunova, Svetlana, Shirokikh, Pavel, Baisheva, Elvira, Martynenko, Vasiliy“…For modelling, we used MaxEnt software with the predictors being climate variables from CHELSA Bioclim, the global digital soil mapping system SoilGrids and the digital elevation model. …”
Publicado 2023
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12623por Li, Hong-Ying, Wei, Ting-Ting, Zhuang, Miao, Tan, Cheng-Ye, Xie, Tian-Hua, Cai, Jiping, Yao, Yong, Zhu, Lingpeng“…Cytoplasm mtDNA activates the cGAS-STING pathway and promotes inflammatory senescence-associated secretory phenotype (SASP) and cell senescence. Meanwhile, iron chelator Deferoxamine (DFO) significantly rescues RPE senescence and retinopathy induced by FAC or D-gal in mice. …”
Publicado 2023
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12624“…Six transmembrane epithelial antigen of the prostate (STEAP) 1–4 are membrane-embedded hemoproteins that chelate a heme prosthetic group in a transmembrane domain (TMD). …”
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12625por Ückert, Anna-Katharina, Rütschlin, Sina, Gutbier, Simon, Wörz, Nathalie Christine, Miah, Mahfuzur R., Martins, Airton C., Hauer, Isa, Holzer, Anna-Katharina, Meyburg, Birthe, Mix, Ann-Kathrin, Hauck, Christof, Aschner, Michael, Böttcher, Thomas, Leist, Marcel“…Neurotoxicity was completely prevented by several iron chelators, by distinct anti-oxidants and by a caspase inhibitor. …”
Publicado 2023
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12626por Bayanbold, Khaliunaa, Singhania, Mekhla, Fath, Melissa A., Searby, Charles C., Stolwijk, Jeffrey M., Henrich, John B., Pulliam, Casey F., Schoenfeld, Joshua D., Mapuskar, Kranti A., Sho, Sei, Caster, Joseph M., Allen, Bryan G., Buettner, Garry R., Spies, Maria, Goswami, Prabhat C., Petronek, Michael S., Spitz, Douglas R.“…The intracellular redox-active labile iron pool (LIP) is weakly chelated and available for integration into the iron metalloproteins that are involved in diverse cellular processes, including cancer cell-specific metabolic oxidative stress. …”
Publicado 2023
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12627“…The first method is based on coupling of 4-aminoantipyrine (4-AAP) with one of the dopamine derivatives (LD, CD) to give a new ligand that reacts with copper tetramine complex to give intensely colored chelates. The colored products are quantified spectrophotometrically at 525 and 520 nm for LD and CD, respectively. …”
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12628por Weaver, Virginia M., Schwartz, Brian S., Jaar, Bernard G., Ahn, Kyu-Dong, Todd, Andrew C., Lee, Sung-Soo, Kelsey, Karl T., Silbergeld, Ellen K., Lustberg, Mark E., Parsons, Patrick J., Wen, Jiayu, Lee, Byung-Kook“…Mean (± SD) tibia, blood, and dimercaptosuccinic acid–chelatable lead levels were 37.2 ± 40.4 μg/g bone mineral, 32.0± 15.0 g/dL, and 0.77± 0.86 μg/mg creatinine, respectively, in 798 current and former lead workers. …”
Publicado 2005
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12629por Rosen, J F, Markowitz, M E, Bijur, P E, Jenks, S T, Wielopolski, L, Kalef-Ezra, J A, Slatkin, D N“…With the development of L X-ray fluorescence (LXRF) to measure cortical bone lead directly, safely, rapidly, and noninvasively, the present study was undertaken to a) evaluate LXRF as a possible replacement for the CaNa2EDTA test; b) quantify lead in tibial cortical bones of mildly to moderately lead-toxic children before treatment; and c) quantify lead in tibial cortical bones of lead-toxic children sequentially following one to two courses of chelation therapy. The clinical research design was based upon a longitudinal assessment of 59 untreated lead-toxic children. …”
Publicado 1991
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12630por Aposhian, H V“…Sodium 2,3-dimercapto-1-propane sulfonate (DMPS, Dimaval) is a water-soluble chelating agent that can be given by mouth or systemically and has been used to treat metal intoxication since the 1960s in the former Soviet Union and since 1978 in Germany. …”
Publicado 1998
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12631por Rosen, J F, Markowitz, M E, Bijur, P E, Jenks, S T, Wielopolski, L, Kalef-Ezra, J A, Slatkin, D N“…With the development of L X-ray fluorescence (LXRF) to measure cortical bone lead directly, safely, rapidly, and noninvasively, the present study was undertaken to a) evaluate LXRF as a possible replacement for the CaNa2EDTA test; b) quantify lead in tibial cortical bones of mildly to moderately lead-toxic children before treatment; and c) quantify lead in tibial cortical bones of lead-toxic children sequentially following one to two courses of chelation therapy. The clinical research design was based upon a longitudinal assessment of 59 untreated lead-toxic children. …”
Publicado 1991
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12632por Scinicariello, Franco, Murray, H. Edward, Moffett, Daphne B., Abadin, Henry G., Sexton, Mary J., Fowler, Bruce A.“…DATA SOURCE: We included studies reporting one or more of the following by individuals with genotypes ALAD1-1 and ALAD1-2/2-2: blood lead level (BLL), tibia or trabecular lead level, zinc protoporphyrin (ZPP), hemoglobin, serum creatinine, blood urea nitrogen (BUN), dimercaptosuccinic acid–chelatable lead, or blood pressure. DATA EXTRACTION: Sample sizes, means, and standard deviations were extracted for the genotype groups. …”
Publicado 2007
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12633por Deslandes, Vincent, Nash, John HE, Harel, Josée, Coulton, James W, Jacques, Mario“…Genes coding for a possible Yfe system (yfeABCD), implicated in the acquisition of chelated iron, were detected, as well as genes coding for a putative enterobactin-type siderophore receptor system. …”
Publicado 2007
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12634por King, D. J., Antoniw, P., Owens, R. J., Adair, J. R., Haines, A. M., Farnsworth, A. P., Finney, H., Lawson, A. D., Lyons, A., Baker, T. S.“…The equilibrium dissociation constant of hA33 (KD = 1.3 nM) was shown to be equivalent to that of the murine antibody in a cell-binding assay. hA33 labelled with yttrium-90 using the macrocyclic chelator 12N4 (DOTA) was shown to localise very effectively to human colon tumour xenografts in nude mice, with tumour levels increasing as blood concentration fell up to 144 h. …”
Publicado 1995
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12635Publicado 1981“…The reformation of the cytoskeleton requires only that the actin be in the filamentous form--no accessory proteins, chelating agents, divalent cations, or energy sources are necessary. …”
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12636Publicado 1982“…Thus intracellulary trapped chelators like quin2 offer a method to measure or buffer [Ca2+]i in hitherto intractable cell types.…”
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12637Publicado 1987“…The purified enzyme is a glycoprotein with an apparent molecular mass of 67 kD by gel filtration and 62 kD by SDS PAGE, and is sensitive to metal ion chelators and SH-blocking agents. These properties are the same as those of the gamete wall-autolysin released into the medium by mating gametes. …”
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12638Publicado 1986“…We show here that a wave of calcium release crosses the Lytechinus pictus egg; the peak of the wave travels with a velocity of 5 microns/s; microinjection of InsP3 causes the release of calcium within the egg; calcium release (as judged by fertilization envelope elevation) is abolished by prior injection of the calcium chelator EGTA; neomycin, an inhibitor of InsP3 production, does not prevent the release of calcium in response to InsP3 but does abolish the wave of calcium release; the egg cytoplasm rapidly buffers microinjected calcium; the calcium concentration required to cause fertilization membrane elevation when microinjected is very similar to that required to stimulate the production of InsP3 in vitro; and the progressive fertilization membrane elevation seen after microinjection of calcium buffers appears to be due to diffusion of the buffer across the egg cytoplasm rather than to the induction of the activation wave. …”
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12639Publicado 1988“…When intracellular Ca++ was buffered with the permeable Ca++ chelator quin2, EGF stimulation was reduced 50%. A similar inhibition of the EGF response was observed when cells were incubated in buffers with high K+ concentrations or in the presence of the K+ ionophore valinomycin. …”
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12640Publicado 1994“…Moreover, the two adhesion systems could be differentially modulated since short treatment with the Ca2+ chelator EGTA, disrupted the cadherin junctions leaving PECAM-1 apparently intact. …”
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