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  1. 12881
    “…CONCLUSION: Hypoparathyroidism was not uncommon in patients with transfusion-dependent thalassemia treated with suboptimal iron chelation. Plasma intact FGF-23 level in hypoparathyroid patients was lower than that of normoparathyroid patients.…”
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    Under-recognized Hypoparathyroidism in Thalassemia
  2. 12882
    “…BACKGROUND: Although the renal toxicity of Deferasirox, an oral iron chelator, has been reported to be mild, there have been reports of acute interstitial nephritis or Fanconi syndrome due to this agent. …”
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    Acute kidney injury due to thin basement membrane disease mimicking Deferasirox nephrotoxicity: a case report
  3. 12883
    “…This study aims to show if the design of multimeric Tz-ligands by chelator scaffolding can improve the binding capacity and may lead to enhanced PET imaging with gallium-68. …”
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    Pretargeted Imaging with Gallium-68—Improving the Binding Capability by Increasing the Number of Tetrazine Motifs
  4. 12884
    “…HMF derivatives also promoted protein synthesis in myotubes, and treatment with the intracellular Ca(2+) chelator BAPTA‐AM, which depletes intracellular Ca(2+) levels, inhibited this promotion. …”
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    5‐Hydroxy‐7‐methoxyflavone derivatives from Kaempferia parviflora induce skeletal muscle hypertrophy
  5. 12885
    “…Herein, we describe the model of toxic demyelination induced by cuprizone (CPZ), a copper chelator that reduces the cytochrome and monoamine oxidase activity into the brain, produces mitochondrial stress and triggers the local immune response. …”
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    Five Decades of Cuprizone, an Updated Model to Replicate Demyelinating Diseases
  6. 12886
    “…Moreover, the addition of an iron chelator worked synergistically with NO in the dispersal of biofilms. …”
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    Nitric Oxide and Iron Signaling Cues Have Opposing Effects on Biofilm Development in Pseudomonas aeruginosa
  7. 12887
    “…In addition, serum cystatin-C and β-2 microglobulin levels were positively correlated with blood urea, serum creatinine, serum ferritin, urinary albumin/creatinine ratio, duration of iron chelating agents and frequency of blood transfusion/year. …”
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    Early Predictors of Renal Dysfunction in Pediatric Patients with Sickle Cell Disease
  8. 12888
    “…The cytoprotective effects of HO-1 depend on several cellular mechanisms including the generation of bilirubin, an anti-oxidant molecule, from the degradation of heme; the induction of ferritin, a strong chelator of free iron; and the release of CO, that displays multiple anti-inflammatory and anti-apoptotic actions. …”
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    Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1
  9. 12889
    “…METHODS: Control Atp7b(+/-) and Wilson disease Atp7b(-/-) rats were fed either a high-calorie diet (HCD) or a normal diet. Copper chelation using the high-affinity peptide methanobactin was used in HCD-fed Atp7b(-/-) rats to test for therapeutic reversal of mitochondrial copper damage. …”
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    A High-Calorie Diet Aggravates Mitochondrial Dysfunction and Triggers Severe Liver Damage in Wilson Disease Rats
  10. 12890
    “…For this, we employed ARL-67156 (ARL), a weak competitive inhibitor of ecto-ATPases, and the calcium chelator EGTA. We show here that, in healing BCE cells, ARL enhances cellular calcium oscillations during the FCW, while EGTA decreases oscillations. …”
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    Calcium Oscillatory Behavior and Its Possible Role during Wound Healing in Bovine Corneal Endothelial Cells in Culture
  11. 12891
    “…In rice (Oryza sativa L.), PA mainly accumulates in rice bran, and chelates mineral cations, resulting in mineral deficiencies among brown rice consumers. …”
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    Novel allelic variant of Lpa1 gene associated with a significant reduction in seed phytic acid content in rice (Oryza sativa L.)
  12. 12892
    “…The coordinatively unsaturated gold(iii) chelate complex [(C^N–CH)Au(C(6)F(5))](+) (1(+)) reacts with main group hydrides H–BPin and H–SiEt(3) in dichloromethane solution at –70 °C to form the corresponding σ-complexes, which were spectroscopically characterized (C^N–CH = 2-(C(6)H(3)Bu(t))-6-(C(6)H(4)Bu(t))pyridine anion; Pin = OCMe(2)CMe(2)O). …”
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    Heterolytic bond activation at gold: evidence for gold(iii) H–B, H–Si complexes, H–H and H–C cleavage
  13. 12893
    “…Hydroalcoholic extract of C. micranthum (CM extract) showed a strong antioxidant activity by scavenging AAPH, DPPH, nitric oxide, hydrogen peroxide and chelating metal ions. CM extract exhibited significant (P < 0.001) dose dependent inhibition of ferric chloride-ascorbic acid induced lipid peroxidation. …”
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    Antioxidant and nephroprotection activities of Combretum micranthum: A phytochemical, in-vitro and ex-vivo studies
  14. 12894
    “…The suggested mechanism of BDC sensor is attributed to the chelation process with Cu(II), to establish a 1:1 metal-ligand ratio complex with a binding constant (K(bind) = 7.16 x 10(4) M(−1)). …”
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    Ultrasensitive Optical Chemosensor for Cu(II) Detection
  15. 12895
    “…When cells were exposed to BK with either a nominal Ca(2+)-free or 1 mM of extracellular Ca(2+) concentration modified Tyrode’s solution, no difference in BK-induced ROS production was observed; however, chelating of cytosolic Ca(2+) by BAPTA/AM or the depletion of ER Ca(2+) contents by thapsigargin eliminated BK-induced ROS production. …”
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    Calcium Release from Endoplasmic Reticulum Involves Calmodulin-Mediated NADPH Oxidase-Derived Reactive Oxygen Species Production in Endothelial Cells
  16. 12896
    “…Conclusions: The experimental results indicate that the entrapment of metal chelates in hydrogel nanostructures offers a versatile platform for developing different high performing CAs for disease diagnosis.…”
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    Water-Mediated Nanostructures for Enhanced MRI: Impact of Water Dynamics on Relaxometric Properties of Gd-DTPA
  17. 12897
    “…The data suggests that gallic acid possibly exerts its effect on T. brucei via iron chelation leading to structural and morphological changes and arrest of the cell cycle. …”
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    In vitro anti-trypanosomal effects of selected phenolic acids on Trypanosoma brucei
  18. 12898
    “…The ΔtptA mutant had decreased resistance to the iron chelator bathophenanthroline disulfonate (BPS) with severe growth defects. …”
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    The mitochondrial thiamine pyrophosphate transporter TptA promotes adaptation to low iron conditions and virulence in fungal pathogen Aspergillus fumigatus
  19. 12899
    “…Background: Deferoxamine (DFO) is a commonly used iron chelator, which can reduce the iron levels in cells. …”
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    Deferoxamine-induced high expression of TfR1 and DMT1 enhanced iron uptake in triple-negative breast cancer cells by activating IL-6/PI3K/AKT pathway
  20. 12900
    por Qiang, Qinping, Wang, Yuhua
    Publicado 2019
    “…In thiswork, we investigate the influence of Mn(2+) on the emission color, thermal sensing and optical heater behavior of NaGdF(4): Yb/Er nanophosphors, which the nanoparticles were synthesized by a hydrothermal method using oleic acid as both a stabilizing and a chelating agent. The morphology and crystal size of upconversion nano particles (UCNPs) can be effectively controlled through the addition of Mn(2+) dopant contents in NaGdF(4): Yb/Er system. …”
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    Effect of Mn(2+) on Upconversion Emission, Thermal Sensing and Optical Heater Behavior of Yb(3+) - Er(3+) Codoped NaGdF(4) Nanophosphors
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