“…Herein, a novel phosphate group functionalized metal–organic framework nanoparticles (denoted as Fe(3)O(4)@SiO(2)@UiO-66-TPP NPs) designed and prepared by the chelation between Zr and phytic acid, showing fast adsorption rate and outstanding selectivity in aqueous media including 10 coexisting ions. …”
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“…Overall, the addition of EGCG at 3% to HC (HC–3% EGCG) increased SH, ABTS radical scavenging and metal chelating activities (p < 0.05). FTIR spectra of HC–3% EGCG revealed the interaction between HC and EGCG via H-bonding and covalent interaction. …”
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“…The significant increase in the sensitivity caused by Cu(2+) could be attributed to the capability of Cu(2+) to form a highly stable chelate complex with surface-immobilized Cys, facilitating the aggregation of AuNPs. …”
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“…A new cationic Pt(II) complex bearing 8-aminoquinoline as chelating ligand (called Pt-8AQ) was evaluated against two human carcinomas, one mesothelioma, and three glioblastoma cell lines. …”
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“…In in vitro studies, AS revealed the strong reducing power and DPPH scavenging effect, but hydroxyl radical scavenging activity and ferrous ions-chelating ability were not strong. Meanwhile, the oxidative stress RAW264.7 cell injury model was established, the low and medium-doses of AS showed significant protective effects on the viability of H(2)O(2)-treated cells by CCK-8 method. …”
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“…The modulation of GSH on the plant in response to environmental stresses could be illustrated through key pathways such as reactive oxygen species (ROS) scavenging and signaling, methylglyoxal (MG) detoxification and signaling, upregulation of gene expression for antioxidant enzymes, and metal chelation and xenobiotic detoxification. However, under extreme stresses, the biosynthesis of GSH may get inhibited, causing an excess accumulation of ROS that induces oxidative damage on plants. …”
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“…BACKGROUND: Nicotianamine (NA), 2′-deoxymugineic acid (DMA), and mugineic acid (MA) are chelators required for iron uptake and transport in plants. …”
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“…Bepridil-induced melanoma cell death came from cell cycle arrest and enhanced apoptosis, which were all attenuated by the Ca(2+) chelator BAPTA-AM. As compared with melanoma, normal melanocytes had lower NCX1 expression and were less sensitive to the cytotoxicity of bepridil. …”
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“…Inhibition of calcineurin by FK506 or cyclosporin A, as well as chelation of extracellular Ca(2+) by BAPTA, exclusively inhibit CAT induction but not germ-tube formation. …”
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“…L-ornithine is a biosynthetic precursor of siderophores, which is synthesized from multimodular large enzyme complexes through non-ribosomal peptide synthetases (NRPSs), while siderophore-Fe chelators cell wall mannoproteins (FIT1, FIT2, and FIT3) help the retention of siderophores. …”
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“…Moreover, the TRPV1 antagonist CPZ, the calcium chelator BAPTA, and the PKA inhibitor H-89 effectively alleviated the redifferentiation exerted by CAP, demonstrating that CAP might improve radioiodine avidity through the activation of the TRPV1‒Ca(2+)/cAMP/PKA/CREB signaling pathway. …”
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“…The guanidine ligand is a product of Schiff base condensation between amino­guanidine, salicyl­aldehyde and 5-bromo­salicyl­aldehyde templated by Ni(2+) ions. The chelating ligand mol­ecule is deprotonated at the phenol O atoms and coordinates the metal centre through the two azomethine N and two phenolate O atoms in a cis-NiN(2)O(2) square-planar configuration [average(Ni—N/O) = 1.8489 Å, cis angles in the range 83.08 (5)–95.35 (5)°, trans angles of 177.80 (5) and 178.29 (5)°]. …”
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“…Up-regulation of TCH4 influenced the ratio of chelator-soluble pectin to alkali-soluble pectin and decreased the degree of methylesterification of pectin under B-deficient conditions. …”
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“…Ferroptosis, a newly identified iron-dependent cell death pattern, can be induced by iron chelators and small lipophilic antioxidants. Nonetheless, the prognostic significance of ferroptosis-related lncRNAs in PC remains to be clarified. …”
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“…All peptides used the DOTA chelator for radiolabeling with either (68)Ga for imaging or (177)Lu for therapy. …”
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“…These results indicated that the antimicrobial activity of bLF against S. scabiei cannot be attributed to its iron-chelating effect but to the bioactivity of its peptides. …”
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“…Among them are siderophores, iron-chelating molecules, that show a great influence on bacterial community assembly and the potential to control pathogen invasions. …”
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“…Previous studies unfolded several routes through which genetic engineering-mediated improvements appear feasible (encompassing sequestration/uptake capacity and specificity for heavy metals); they can be categorized as metal transportation, chelation, or biotransformation, with regulation of metal- and oxidative stress response, as well as cell surface engineering playing a crucial role therein. …”
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“…Also innovative is the cephalosporin derivative cefiderocol, which incorporates an iron-chelating siderophore that facilitates Gram-negative bacteria cell entry. …”
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“…We therefore investigated the in vitro and in vivo preclinical efficacy of four SVMP inhibitors to neutralise the effects of D. typus venom; the matrix metalloproteinase inhibitors marimastat and prinomastat, and the metal chelators dimercaprol and DMPS. The venom of D. typus exhibited an SVMP-driven procoagulant phenotype in vitro. …”
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