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  1. 13401
    “…Likewise, emptying Ca(2+) stores with cyclopiazonic acid or the chelation of intracellular Ca(2+) with BAPTA-AM prevented the frequency increase, suggesting that the frequency increase was caused by presynaptic store release. …”
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    Noradrenaline Increases mEPSC Frequency in Pyramidal Cells in Layer II of Rat Barrel Cortex via Calcium Release From Presynaptic Stores
  2. 13402
    “…Gigantic spontaneous events were eliminated by application of TTX–or by lowered or chelated Ca(2+)–suggesting that gigantic events were elicited by spontaneous nerve firing. …”
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    Drosophila Ca(V)2 channels harboring human migraine mutations cause synapse hyperexcitability that can be suppressed by inhibition of a Ca(2+) store release pathway
  3. 13403
    “…Char structure, which varies widely according to the pyrolysis process and the nature of feedstock, is thought to be a major factor in the interaction of chars with soil and their metal ion adsorption/chelation properties. Furthermore, biochar nutrients and their elemental content can modify soil fertility. …”
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    Structural and Functional Features of Chars From Different Biomasses as Potential Plant Amendments
  4. 13404
    “…The magnitude of the SFK response to hyposmotic solution was reduced by a TRPV4 antagonist HC067047 added to prevent TRPV4-mediated calcium entry, and by a cytoplasmic Ca(2+) chelator BAPTA-AM. The Na,K-ATPase activity response in the epithelium of lenses exposed to hyposmotic solution was abolished by BAPTA-AM. …”
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    A Role for Calcium-Activated Adenylate Cyclase and Protein Kinase A in the Lens Src Family Kinase and Na,K-ATPase Response to Hyposmotic Stress
  5. 13405
    “…Both species showed significant antioxidant activity as revealed by DPPH, FRAP, ABTS, and metal chelating assays. H. humifusum exhibited a strong acetylcholinesterase (3.86–4.57 mg GALAEs/g), α-glucosidase (0.73–2.55 mmol ACEs/g) and α-amylase (3–8 mmol ACEs/g) inhibitory activity. …”
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    Bioactive compounds from Hypericum humifusum and Hypericum perfoliatum: inhibition potential of polyphenols with acetylcholinesterase and key enzymes linked to type-2 diabetes
  6. 13406
    “…Removal of the calcium ion from this site by chelation or mutagenesis shifts the equilibrium to Cu(2+)-TPQ(AMQ) or destabilizes Cu(+)-TPQ(SQ). …”
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    Oxygen Activation Switch in the Copper Amine Oxidase of Escherichia coli
  7. 13407
    “…Besides antioxidant activity of the extract was evaluated by a 2,2-diphenyl-1-picrylhydarzyl (DPPH) and 2,2′-azinobis-(3-ethylbenzthiazoline-6-sulphonate (ABTS) radical scavenging assay, ferric reducing power assay and chelation of ferrous ions assay, and then anticaner activity was also researched against A549 cell line and 7721 cell line. …”
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    Optimization of Ionic Liquid-Assisted Extraction of Biflavonoids from Selaginella doederleinii and Evaluation of Its Antioxidant and Antitumor Activity
  8. 13408
    por Šarenac, Tanja M., Mikov, Momir
    Publicado 2018
    “…Also, the effects of BAs on digestion of nutrients, their role as drugs, and, in particular, the emphasis on the hypoglycemic properties of 7α, 12α-dihydroxy−12–keto−5β-cholanic acid in the treatment of diabetes mellitus are examined in detail.…”
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    Bile Acid Synthesis: From Nature to the Chemical Modification and Synthesis and Their Applications as Drugs and Nutrients
  9. 13409
    “…In addition, the association with N-acetylcysteine (a glutathione donor) and deferoxamine (an iron chelator) could improve the antioxidant cardioprotection by ascorbate, making it even more effective in preventing myocardial reperfusion damage associated with PCA following AMI.…”
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    Myocardial reperfusion injury and oxidative stress: Therapeutic opportunities
  10. 13410
    por Akbarian, Mohsen, Yousefi, Reza
    Publicado 2018
    “…A large amount of the recombinant fusion proteins with high purity was obtained by applying a single step anion exchange chromatography or metal chelate affinity. The insulin A- and B-chain were released from the fusion proteins using cyanogen bromide cleavage. …”
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    Human αB-crystallin as fusion protein and molecular chaperone increases the expression and folding efficiency of recombinant insulin
  11. 13411
    “…H9c2 myocytes stimulated with high-glucose concentration or Ca(2+) time-dependently increased NFATc and resistin expression while addition of the Ca(2+) chelator BAPTA-AM attenuated this effect. NFATc expression was enhanced in hearts from ob/ob diabetic and from cardiac-specific Serca2a(−/−) mice. …”
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    A role for calcium in resistin transcriptional activation in diabetic hearts
  12. 13412
    “…A High Performance Liquid Chromatography method combined with UV detection was developed and validated for measurement the concentration of produced HA. The chelation ability of OS extract and its reference compounds was evaluated by tetramethylmurexide reagent. …”
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    Flavonoids-Rich Orthosiphon stamineus Extract as New Candidate for Angiotensin I-Converting Enzyme Inhibition: A Molecular Docking Study
  13. 13413
    “…B. siamensis H30-3 was found to produce siderophore, a high affinity iron-chelating compound. Expressions of BrChi1 and BrGST1 genes were up-regulated in Chinese cabbage leaves by B. siamensis H30-3. …”
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    Enhanced Tolerance of Chinese Cabbage Seedlings Mediated by Bacillus aryabhattai H26-2 and B. siamensis H30-3 against High Temperature Stress and Fungal Infections
  14. 13414
    “…Cardiac targeting peptide was labeled with Technetium 99m ((99m)Tc) using the chelator hydrazino-nicotinamide (HYNIC), and imaging performed using micro-single photon emission computerized tomography/computerized tomography (SPECT/CT). …”
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    Cardiac Targeting Peptide, a Novel Cardiac Vector: Studies in Bio-Distribution, Imaging Application, and Mechanism of Transduction
  15. 13415
    por Xu, Na, Lu, Yi, Hou, Jumin, Liu, Chao, Sun, Yonghai
    Publicado 2018
    “…Results showed that NMCP-2 with an average molecular weight of 48.3 kDa possessed a much stronger chelating ability on ferrous ions and a higher ability to scavenge radical scavenging 2,2-diphenyl-1-picrylhydrazyl (DPPH) than the other purified fraction of NMCP-1 from M. conica. …”
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    A Polysaccharide Purified from Morchella conica Pers. Prevents Oxidative Stress Induced by H(2)O(2) in Human Embryonic Kidney (HEK) 293T Cells
  16. 13416
    “…Moreover, antioxidant activity of TBF extract was analyzed by four methods, i.e., 2,2-di(4-tert-octylphenyl)-1-picrylhydrazyl (DPPH) and 2,2′-azinobis-(3-ethylbenzth-iazoline-6-sulphonate (ABTS) free radical scavenging assay, ferric ion reducing power assay, and chelation of ferrous ions assay. The results indicated that [C(6)mim]PF(6) had a high selectivity and efficiency. …”
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    Ionic Liquid–Ultrasound-Based Extraction of Biflavonoids from Selaginella helvetica and Investigation of Their Antioxidant Activity
  17. 13417
    “…HT-29, Caco-2, and T84 cells were subjected to normoxia or hypoxia in the presence of iron or the iron chelator deferoxamine. Changes in inflammatory gene expression and signaling were assessed by quantitative polymerase chain reaction and Western blot. …”
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    Iron Prevents Hypoxia-Associated Inflammation Through the Regulation of Nuclear Factor-κB in the Intestinal Epithelium
  18. 13418
    “…Importantly, ferrostatin-1 and iron chelation also ameliorated heart failure induced by both acute and chronic I/R in mice. …”
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    Ferroptosis as a target for protection against cardiomyopathy
  19. 13419
    “…Using EGTA (a putative extracellular Ca(2+) chelator) and LaCl(3) (a plasma membrane Ca(2+) channel blocker), we demonstrated that DMF induced a cytosolic Ca(2+) burst via extracellular Ca(2+) and Ca(2+) channels in T. reesei, and that the cytosolic Ca(2+) burst induced by DMF-mediated overexpression of cellulase through calcium signaling. …”
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    N,N-dimethylformamide induces cellulase production in the filamentous fungus Trichoderma reesei
  20. 13420
    “…CONCLUSIONS/SIGNIFICANCE: The data suggests that rosmarinic acid exerts its anti-leishmanial effect via iron chelation resulting in variable morphological changes and cell cycle arrest.…”
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    In vitro activity and mode of action of phenolic compounds on Leishmania donovani
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