“…Activation of ASK1 and p38 was blocked by IP3R inhibitor and a Ca(2+) chelator. Importantly, PAS-Na treatment improved the Pb-induced effects on cognitive deficits in rats, concomitant with rescued neuronal apoptosis. …”
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“…The stability of milk proteins is affected by changes in the pH value of milk, the heating temperature, and the addition of calcium compounds or chelating agents, which can cause alterations in calcium distribution. …”
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“…In conclusion, a complex signal network regulated by NO-mediated CsALMTs revealed that CsALMT8 was regulated by environmental Al(3+) and NO to assist Al(3+) entry into pollen tubes; CsALMT5 might be influenced by the Al(3+) signal, stimulate malate efflux in vacuoles and chelate with Al(3+) to detoxify Al in C. sinensis pollen tube.…”
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“…This work demonstrates the versatility of phenyl-triazole derivatives as cyclometalating ligands with different chelation modes (i.e., C(∧)N and C(∧)C:) for the synthesis of photoactive iridium(III) complexes with highly tunable properties.…”
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“…[Image: see text] Anion-responsive sign inversion of circularly polarized luminescence (CPL) was successfully achieved by N(3)O(6)-type nona-coordinated europium(III) (Eu(3+)) complexes [(R)-1 and (S)-1] composed of a less-hindered unsymmetrical N(3)-tridentate ligand (a chiral bis(oxazoline) ligand) and three O(2)-chelating (β-diketonate) ligands. Here, (R)-1 exhibited a positive CPL signal (I(L) – I(R) > 0) at the (5)D(0) → (7)F(1) transition of Eu(3+), which can be changed to a negative sign (i.e., I(L) – I(R) > 0 → I(L) – I(R) < 0) by the coordination of trifluoroacetic anions (CF(3)COO(–)) to the Eu(3+) center. …”
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“…Moreover, pretreatment of cells with BAPTA-AM, a cytosolic Ca(2+) chelator, dramatically rescued KP372-1- or combination treatment-induced lethality and significantly suppressed PAR formation and γH2AX activation. …”
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“…The TD-SCD patients were on top-up transfusion and oral iron chelation therapy (Exjade). All had high LIC, but 2/6 had SF <500 ng/mL. …”
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“…Regular transfusion and chelation therapy produces increased life expectancy in thalassaemic patients who may develop new complications. …”
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“…Using 10 evaluation indices, namely the scavenging capacity of 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH•), 2,2′‐azino‐bis‐(3‐ethylbenzthiazoline‐6‐sulfonic acid) (ABTS(+)), hydroxyl (OH•) and superoxide anion (O(2) (–)), the Fe(2+) chelating capacity, the content of anthocyanin, flavone, soluble dietary fiber, reducing sugar and protein, antioxidant activity, and functional components of CCCP prepared by different methods were compared. …”
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“…This drawback could result in a more toxic effluent. The use of chelating agents such as Fe(3+)-EDDS to perform solar photo-Fenton at neutral pH was compared to the application of intermittent additions of Fe(2+) and both of these strategies were reported as effective to remove CECs from MSE. …”
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“…Background With optimum transfusion and chelation therapy, the survival of β-thalassemia patients and the incidence of various complications, including renal complications, have improved. …”
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“…The maximum adsorption capacity of Cu(II) and sodium oleate calculated from Langmuir adsorption isotherm equation reached 448.43 mg·g(−1) and 129.03 mg·g(−1), respectively. Chelation and complexation were considered as the main driving forces of Cu(II) adsorption, and the van der Waals force as well as weak hydrogen bonds were considered the main driving forces of sodium oleate adsorption. …”
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“…These factors pose a challenge, over establishing if iron chelation or iron flooding acts as a better approach towards antitumour therapies. …”
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“…In vitro antioxidant assays showed that the REPS possesses a DPPH radical scavenging ability of 43.60% at 5 mg/ml, reducing power of 1.108 at 10 mg/ml, and iron chelation activity of 72.49% and 89.78% at 5 mg/ml and 10 mg/ml, respectively. …”
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“…This study aimed to investigate the protective effects and underlying mechanisms of physiological unconjugated (UC) hyperbilirubinemia mediated by UGT1A1 antisense oligonucleotide in a mouse model of CsA-induced chronic kidney disease, and match these with that of chitosan (CH) as a natural chelator against kidney injury. In the current study, CsA-treated mice were given an intravenous injection of UGT1A1 antisense morpholino oligonucleotide (16 µg/kg) every third day for 14 days. …”
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“…Furthermore, reducing zinc levels by chemical chelation in the sbp-1 mutant also increased lipids and rescued Orsay virus RNA levels. …”
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“…Using two previously discovered HER2-targeting peptides, we modified each peptide with the chelator DOTA and a PEG(2) linker resulting in DOTA-PEG(2)-GSGKCCYSL (P5) and DOTA-PEG(2)-DTFPYLGWWNPNEYRY (P6). …”
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“…Using a rigid tridentate chelate ligand, in which a central cyclometalated phenyl unit is flanked by two coordinating N-heterocyclic carbenes, along with a monodentate isocyanide ligand, a very strong ligand field is created. …”
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“…Peptide receptor radionuclide therapy (PRRT) has over the last two decades emerged as a very promising approach to treat neuroendocrine tumors (NETs) with rapidly expanding clinical applications. By chelating a radiometal to a somatostatin receptor (SSTR) ligand, radiation can be delivered to cancer cells with high precision. …”
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“…The antioxidant potential of the defatted meal methanolic extracts was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP), and metal ion-chelating activity (MIC) assays. The highest total phenolic content of 3.15 mg gallic acid equivalent/g dry weight was recorded in the defatted meal extract from seeds pre-treated with air frying at 190 °C for 15 min. …”
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