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  1. 1361
    “…Monitoring cellular iron levels during “off-label” administration of the FDA-approved iron chelator deferiprone evidenced significant reductions in tumor size without extensive perturbation to these iron deposits. …”
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    Iron deposition is associated with differential macrophage infiltration and therapeutic response to iron chelation in prostate cancer
  2. 1362
    “…Their sensitivity is reported as greatly improved in comparison to commercially used chelate-based ones. The present work is aimed at revealing the factors governing the efficiency of longitudinal magnetic relaxivity (r(1)) in aqueous colloids of core-shell Gd(III)-based nanoparticles. …”
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    Hydration number: crucial role in nuclear magnetic relaxivity of Gd(III) chelate-based nanoparticles
  3. 1363
    “…Complexes with copper(ii) include a single chelate and chloride ion(s)/water to satisfy a trigonal bipyramidal coordination sphere. …”
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    A new triazine bearing a pyrazolone group capable of copper, nickel, and zinc chelation
  4. 1364
    “…Chromosome 22q13.3 deletion (Phelan McDermid) syndrome (PMS) is a rare genetic neurodevelopmental disorder resulting from deletions or other genetic variants on distal 22q. …”
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    Identification of 22q13 genes most likely to contribute to Phelan McDermid syndrome
  5. 1365
    “…To address this problem, we find that the orally-available metal decorporation agent 3,4,3-LI(1,2-HOPO) demonstrates superior efficacy at chelating and removing Gd from the body compared to diethylenetriaminepentaacetic acid, a ligand commonly used in the United States in the GBCA Gadopentetate (Magnevist). …”
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    Evaluating the potential of chelation therapy to prevent and treat gadolinium deposition from MRI contrast agents
  6. 1366
    “…The high resistance of this catalytic system to β-hydride elimination of the alkyl nucleophile is attributed to its chelation to iron through ligation of carbon and one oxygen of the acetal moiety of the nucleophile. …”
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    NHC and nucleophile chelation effects on reactive iron(ii) species in alkyl–alkyl cross-coupling
  7. 1367
    por Shah, Jayshree, McKiernan, Phyllis
    Publicado 2016
    “…However, the currently available iron chelation therapies are associated with side effects, financial constraints, and dosing issues, which may affect patient adherence. …”
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    Optimizing Communication and Adherence to Iron Chelation Therapy From Diagnosis to Treatment in Patients With Myelodysplastic Syndromes
  8. 1368
    “…Due to its 4 carbonic acid groups being available for bioconjugation, the cyclen tetraphosphinate chelator DOTPI, 1,4,7,10-tetraazacyclododecane-1,4,7, 10-tetrakis[methylene(2-carboxyethylphosphinic acid)], represents an ideal scaffold for synthesis of tetrameric bioconjugates for labeling with radiolanthanides, to be applied as endoradiotherapeuticals. …”
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    Synthesis of Symmetrical Tetrameric Conjugates of the Radiolanthanide Chelator DOTPI for Application in Endoradiotherapy by Means of Click Chemistry
  9. 1369
    “…There is a growing interest in the development of new iron chelators as novel promising therapeutic strategies for neurodegenerative disorders. …”
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    The mono(catecholamine) derivatives as iron chelators: synthesis, solution thermodynamic stability and antioxidant properties research
  10. 1370
    “…RESULTS: Generally, iron chelation achieved via CP94 or AP2‐18 administration significantly increased PpIX fluorescence. …”
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    An experimental investigation of a novel iron chelating protoporphyrin IX prodrug for the enhancement of photodynamic therapy
  11. 1371
    “…Five new bis(3-hydroxy-4-pyridinone) tetradentate chelators were synthesized in this study. The structures of these tetradentate chelators were characterized by (1)H-NMR, (13)C-NMR, FT-IR, UV-vis, and mass spectral analyses. …”
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    Synthesis of New Bis(3-hydroxy-4-pyridinone) Ligands as Chelating Agents for Uranyl Complexation
  12. 1372
    “…CONCLUSIONS: Administration of the chelating agent Ca-DTPA 7 weeks after injection of linear gadodiamide induced relevant urinary Gd excretion. …”
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    Impact of Treatment With Chelating Agents Depends on the Stability of Administered GBCAs: A Comparative Study in Rats
  13. 1373
    “…We focused our interest on the design of chelators to address Mycobacterium avium infections. …”
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    Tuning the Anti(myco)bacterial Activity of 3-Hydroxy-4-pyridinone Chelators through Fluorophores
  14. 1374
    “…Dimercaptosuccinic acid (DMSA) is an oral heavy metal chelator. Although DMSA is the most acceptable chelator in the urinary excretion of toxic elements from children and adults, its defects in plasma binding and the membrane permeability limit its interaction with intracellular elements and affect its efficacy in chelation therapy. …”
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    Construction of a Glutathione-Responsive and Silica-Based Nanocomposite for Controlled Release of Chelator Dimercaptosuccinic Acid
  15. 1375
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    Single-center retrospective study of the effectiveness and toxicity of the oral iron chelating drugs deferiprone and deferasirox
  16. 1376
    “…Additionally, current Ln(3+) chelator syntheses complicate efforts to directly incorporate Ln(3+) chelators into proteins as the multi-step processes and a reliance on organic solvents promote protein denaturation and aggregation which are generally incompatible with direct incorporation into the protein of interest. …”
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    Aqueous synthesis of a small-molecule lanthanide chelator amenable to copper-free click chemistry
  17. 1377
    “…The use of synthetic chelates to prevent or correct iron-deficiency is not satisfactory mainly due to their poor biodegradability. …”
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    Comparison of five bacterial strains producing siderophores with ability to chelate iron under alkaline conditions
  18. 1378
    por Tabet, Anne-Claude, Rolland, Thomas, Ducloy, Marie, Lévy, Jonathan, Buratti, Julien, Mathieu, Alexandre, Haye, Damien, Perrin, Laurence, Dupont, Céline, Passemard, Sandrine, Capri, Yline, Verloes, Alain, Drunat, Séverine, Keren, Boris, Mignot, Cyril, Marey, Isabelle, Jacquette, Aurélia, Whalen, Sandra, Pipiras, Eva, Benzacken, Brigitte, Chantot-Bastaraud, Sandra, Afenjar, Alexandra, Héron, Delphine, Le Caignec, Cédric, Beneteau, Claire, Pichon, Olivier, Isidor, Bertrand, David, Albert, El Khattabi, Laila, Kemeny, Stephan, Gouas, Laetitia, Vago, Philippe, Mosca-Boidron, Anne-Laure, Faivre, Laurence, Missirian, Chantal, Philip, Nicole, Sanlaville, Damien, Edery, Patrick, Satre, Véronique, Coutton, Charles, Devillard, Françoise, Dieterich, Klaus, Vuillaume, Marie-Laure, Rooryck, Caroline, Lacombe, Didier, Pinson, Lucile, Gatinois, Vincent, Puechberty, Jacques, Chiesa, Jean, Lespinasse, James, Dubourg, Christèle, Quelin, Chloé, Fradin, Mélanie, Journel, Hubert, Toutain, Annick, Martin, Dominique, Benmansour, Abdelamdjid, Leblond, Claire S., Toro, Roberto, Amsellem, Frédérique, Delorme, Richard, Bourgeron, Thomas
    Publicado 2019
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    Author Correction: A framework to identify contributing genes in patients with Phelan-McDermid syndrome
  19. 1379
    “…CONCLUSIONS: Gadopiclenol is a new extracellular and macrocyclic Gd chelate that exhibited high relaxivity, no protein binding, and high kinetic inertness. …”
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    Physicochemical and Pharmacokinetic Profiles of Gadopiclenol: A New Macrocyclic Gadolinium Chelate With High T1 Relaxivity
  20. 1380
    “…The hydration resistance of CaO materials prepared by Ca(OH)(2) calcination with chelating compounds are investigated in this paper. …”
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    Hydration Resistance of CaO Material Prepared by Ca(OH)(2) Calcination with Chelating Compound
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