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13921por Wang, Yihan, Zhang, Gongyou, Huang, Ya, Guo, Min, Song, Juhui, Zhang, Tingting, Long, Yaohang, Wang, Bing, Liu, Hongmei“…Siderophilic bacteria, as an important type of PGPR, can secrete siderophores to chelate unusable Fe(3+) in the soil for plant growth. …”
Publicado 2022
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13922por Dzakovich, Michael, Debelo, Hawi, Albertsen, Marc, Che, Ping, Jones, Todd, Simon, Marissa, Zhao, Zuo-Yu, Ferruzzi, Mario“…A steeping step prior to porridge production to pre-activate phytase drastically reduced phytate content, altered the profile of inositol phosphate conversion products, and reduced molar ratios of phytate to iron and zinc; preventing the chelation of minerals by phytate and enhancing their bioaccessibility. …”
Publicado 2022
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13923por Lin, Dongxu, Zhang, Mengyang, Luo, Changcheng, Wei, Pengyu, Cui, Kai, Chen, Zhong“…METHODS: The experimental autoimmune prostatitis (EAP) was established through intradermal immunization of prostate extract. Iron chelator deferoxamine (DFO) and free radical scavenger edaravone (EDA) were applied to evaluate the effects of ferroptosis inhibition on oxidative stress, ferroptosis, inflammation, fibrosis, and mast cell activation in the context of CP/CPPS. …”
Publicado 2022
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13924“…In this study, an in vitro digestion was used to elucidate the iron dialysability, and hence estimate iron availability, in the presence of native, chelating resin (Chelex)-treated, oxidised, or partially hydrolysed oat and barley β-glucan extracts (at 1% actual β-glucan concentration), with or without phytase treatment. …”
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13925“…In total, 1,080 Jinghong-1 laying hens aged 57 weeks were randomly assigned to five treatment groups: CON, basal diet containing about 6, 29, 49, and 308 mg·kg(−1) of Cu, Mn, Zn, and Fe; IT100, basal diet supplemented with 10, 80, 80, and 60 mg·kg(−1) of Cu, Mn, Zn, and Fe (each as inorganic sulfates), respectively; OT20, basal diet supplemented with 2, 16, 16, and 12 mg·kg(−1) of Cu, Mn, Zn, and Fe (each as organic trace minerals chelated with lysine and methionine in the ratio of 2:1 amino acid: organic trace minerals), respectively; OT30, basal diet supplemented with 3, 24, 24, and 18 mg·kg(−1) of organic Cu, Mn, Zn, and Fe, respectively; and OT50, basal diet supplemented with 5, 40, 40, and 30 mg·kg(−1) of organic Cu, Mn, Zn, and Fe, respectively. …”
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13926“…Diverse “non-traditional agents” including bacteriophages, iron mimetic/chelator, and anti-virulence factors are significantly represented but unfortunately still in early clinical stages. …”
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13927“…Regarding antioxidant properties, LUCS technology on HepG2 cells evidenced the ability of SP4(TM) to neutralize intracellular free radicals, inhibit membrane lipid peroxidation, quench H(2)O(2), and reduce free radicals mainly through chelating mechanism, as demonstrated by a higher FRAP value (2643.28 ± 39.86 mmol/g) compared with ABTS (139.92 ± 6.16 mmol/g) and DPPH (89.51 ± 3.91 mmol/g). …”
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13928por Jimenez-Pulido, Ivan Jesus, Daniel, Rico, Perez, Jara, Martínez-Villaluenga, Cristina, De Luis, Daniel, Martín Diana, Ana Belén“…The highest protein content in WB produced a significant (p ≤ 0.05) reduction in GI value, probably due to the role of protein structure in protecting starch from gelatinization, along with phytic acid, which may bind to proteins closely associated to starch and chelate calcium ions, required for α-amylase activity. …”
Publicado 2022
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13929“…Multiple factors are responsible for the pathogenesis of bone loss in thalassemia, including diabetes, hypothyroidism, parathyroid gland dysfunction, accelerated hemopoiesis, direct iron toxicity of osteoblasts, iron chelators, and deficiencies of growth hormone or insulin growth factors. …”
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13930“…Additionally, cells were pre-treated for 24 h with si-NOX4, for 1 h with the iron chelator deferoxamine mesylate (DFO) or for 1 h with the lipid peroxidation inhibitor liproxstatin-1 before being treated with XN4 to analyse the mechanism of XN4. …”
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13931por Buerkli, Simone, Salvioni, Laura, Koller, Natalie, Zeder, Christophe, Teles, Maria José, Porto, Graça, Habermann, Jana Helena, Dubach, Irina Léa, Vallelian, Florence, Frey, Beat M., Moretti, Diego, Baumgartner, Jeannine, Zimmermann, Michael B.“…OBJECTIVES: We developed a natural polyphenol supplement that strongly chelates iron in vitro and assessed its effect on non-heme iron absorption in patients with hereditary hemochromatosis (HH). …”
Publicado 2022
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13932“…The mechanism of adsorption of the investigated heavy metals, is probably based on the chelation between the metal ions and the N donors of DiCu.MC. …”
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13933por Zhang, Yanqin, Liu, Xinyu, Deng, Mengqi, Xu, Chunyu, Zhang, Yubo, Wu, Di, Tang, Fan, Yang, Ruiye, Miao, Jinwei“…However, disruption of intracellular iron levels or ferroptosis via chelation of intracellular iron deferoxamine mesylate or ferroptosis inhibitor ferrostatin-1 could reverse this process, indicating that iron-induced ferroptosis plays a vital role in ovarian EMs fibrosis. …”
Publicado 2022
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13934por Orcutt, Kelly D., Henry, Kelly E., Habjan, Christine, Palmer, Keryn, Heimann, Jack, Cupido, Julie M., Gottumukkala, Vijay, Cissell, Derek D., Lyon, Morgan C., Hussein, Amira I., Liu, Dijie, Li, Mengshi, Johnson, Frances L., Schultz, Michael K.“…[(212)Pb]VMT01 is a melanocortin 1 receptor (MC1R) targeted theranostic ligand in clinical development for alpha particle therapy for melanoma. (212)Pb has an elementally matched gamma-emitting isotope (203)Pb; thus, [(203)Pb]VMT01 can be used as an imaging surrogate for [(212)Pb]VMT01. [(212)Pb]VMT01 human serum stability studies have demonstrated retention of the (212)Bi daughter within the chelator following beta emission of parent (212)Pb. …”
Publicado 2022
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13935por Gao, Zhihua, Zheng, Peijing, Wang, Kuang, Ji, Xin, Shi, Yanqing, Song, Xuecheng, Liu, Jingze, Yu, Zhijun, Yang, Xiaolong“…In vitro experiments showed that rHrFer1 and rHrFer2 had concentration-dependent iron chelating activity. The relative expression of the two ferritin genes was higher in the ovary and midgut of H. rufipes. …”
Publicado 2022
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13936“…These results suggest that Pe-Cu/Zn SOD played a role in Cd detoxification by chelating heavy metal ions and scavenging reactive oxygen free radicals, and that P. esculenta could be used as a bioindicator to evaluate heavy metal pollution.…”
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13937“…The TPC values for PDOPA1@HNT, PDOPA3@HNT and PDOPA5@HNT coatings were found to be 405.5 ± 25.0, 750.0 ± 69.9, and 1348.3 ± 371.7 µmol GA equivalents, respectively. The Fe(II) chelation capacity of HNT was found to be 20.5% ± 1.2%, while the PDOPA1@HNT, PDOPA3@HNT and PDOPA5@HNT values were found to be 49.9 ± 6.5, 36.6 ± 12.7 and 25.4 ± 1.2%, respectively. …”
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13938por Aziz, Marya, Ahmad, Saeed, Khurshid, Umair, Pervaiz, Irfan, Lodhi, Arslan Hussain, Jan, Nasrullah, Khurshid, Sameera, Arshad, Muhammad Adeel, Ibrahim, Mohamed M., Mersal, Gaber A. M., Alenazi, Fahaad S., Awadh Saleh Alamri, Ahmed, Butt, Juwairiya, Saleem, Hammad, El-Bahy, Zeinhom M.“…The phosphomolybdenum assay revealed that the n-hexane fraction showed the most efficient results, while maximum metal chelation potential was observed for the chloroform fraction. …”
Publicado 2022
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13939“…And cuproptosis induced by copper overload targeting lipoylated tricarboxylic acid cycle proteins, is closely related to mitochondrial respiration. Copper chelators not only treat HF but also partially rescue copper-mediated cell death. …”
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13940“…OsFER2 complementation in ΔOsfer2 knock-out mutants restored ROS and iron accumulation and HR cell death phenotypes during infection. The iron chelator deferoxamine, the lipid-ROS scavenger ferrostatin-1, the actin microfilament polymerization inhibitor cytochalasin E and the redox inhibitor diphenyleneiodonium suppressed ROS and iron accumulation and HR cell death in rice leaf sheaths. …”
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