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14061“…The Co(III) ion is hexacoordinated by two C-bonded axial cyanide ligands and the four pyrrole N atoms of the porphyrin ligand. The K(I) ion is chelated by the six O atoms of the 18-crown-6 molecule and is further coordinated by two O atoms of pivalamido groups of the porphyrin ligands, leading to the formation of polymeric chains running along [011]. …”
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14062por Sangvanich, Thanapon, Morry, Jingga, Fox, Cade, Ngamcherdtrakul, Worapol, Goodyear, Shaun, Castro, David, Fryxell, Glen E., Addleman, Raymond S., Summers, Anne O., Yantasee, Wassana“…In simulated gastrointestinal fluids, SH-SAMMS had a very high affinity (K(d)) for methyl mercury (MeHg(I)), inorganic mercury (Hg(II)), lead (Pb(II)), and cadmium (Cd(II)) and was superior to other SAMMS with carboxylic acid or phosphonic acid ligands or commercially available metal chelating sorbents. SH-SAMMS also effectively removed Hg from biologically digested fish tissue with no effect on most nutritional minerals found in fish. …”
Publicado 2014
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14063por Halabi, Mohammed Farouq, Shakir, Raied Mustafa, Bardi, Daleya Abdulaziz, Al-Wajeeh, Nahla Saeed, Ablat, Abdulwali, Hassandarvish, Pouya, Hajrezaie, Maryam, Norazit, Anwar, Abdulla, Mahmood Ameen“…ETHAB results showed antioxidant activity in the DPPH, FRAP, nitric oxide and metal chelating assays. There was no acute toxicity even at the highest dosage (1000 mg/kg). …”
Publicado 2014
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14064“…The expressed peptide was purified using metal-chelate affinity chromatography and used as antigen in developing a blot immunoassay. …”
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14065por Bora, Arijit, Sanjana, Rajkumari, Jha, Brajesh Kumar, Narayan Mahaseth, Surya, Pokharel, Khilasa“…MBL production was detected by performing combined disc test by using imipenem discs with and without ethylenediaminetetraacetic acid (EDTA), which chelates zinc required for MBL activity. RESULTS: Out of 216 E. coli isolates, a total of 41 isolates (18.98%) and out of 185 K. pneumoniae isolates, a total of 39 isolates (21.08%) were suspected to be carbapenemase- producers on the basis of their reduced susceptibility to meropenem or ertapenem. …”
Publicado 2014
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14066por Jabaji, Ziyad, Brinkley, Garrett J., Khalil, Hassan A., Sears, Connie M., Lei, Nan Ye, Lewis, Michael, Stelzner, Matthias, Martín, Martín G., Dunn, James C. Y.“…Small intestinal crypts were isolated using EDTA chelation. Intestinal subepithelial myofibroblasts were isolated from a pediatric sample and expanded in vitro. …”
Publicado 2014
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14067por Zhang, Jingyao, Wu, Jiaxin, Wang, Weiran, Wu, Hui, Yu, Bin, Wang, Jiawen, Lv, Mingyu, Wang, Xiaodan, Zhang, Haihong, Kong, Wei, Yu, Xianghui“…While the membrane-permeable zinc chelator TPEN could block BIV Vif-mediated degradation of btA3Z2-Z3, it had minimal effects on oaA3Z2-Z3 degradation induced by MVV Vif, indicating that Zn is important for the activity of BIV Vif but not MVV Vif. …”
Publicado 2014
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14068por Liu, Yaoming, Wu, Haihua, Kou, Lihua, Liu, Xiaojian, Zhang, Jianzhen, Guo, Yaping, Ma, Enbo“…These motifs might serve as primary chelating sites, as in other organisms. These characteristics suggest that OcMT1 and OcMT2 may be involved in heavy metal detoxification by capturing the metals. …”
Publicado 2014
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14069por Lamboley, Cédric R.H., Kake Guena, Sandrine A., Touré, Fatou, Hébert, Camille, Yaddaden, Louiza, Nadeau, Stephanie, Bouchard, Patrice, Wei-LaPierre, Lan, Lainé, Jean, Rousseau, Eric C., Frenette, Jérôme, Protasi, Feliciano, Dirksen, Robert T., Pape, Paul C.“…We describe a new method for determining the concentration of total Ca in whole skeletal muscle samples ([Ca(T)](WM) in units of mmoles/kg wet weight) using the Ca-dependent UV absorbance spectra of the Ca chelator BAPTA (1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid). …”
Publicado 2015
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14070“…The LPA effect was also attenuated by ethylene glycolbis(β-aminoethylether)-N,N,N′,N′-tetraacetic acid (EGTA), an extracellular Ca(2+) chelator, Ni(2+) and KB-R7943, inhibitors of the Na(+)-Ca(2+) exchanger; the receptor operated Ca(2+) channel (ROC) blockers, 2-aminoethoxydiphenyl borate and SK&F 96365. …”
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14071“…To assess the contribution of intracellular copper transport to E1 inhibition, coincubations were performed with the copper chelator triethylenetetramine hydrochloride (TET). …”
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14072“…The RING-like core is preserved in the UBR-box and the metal-chelating motifs display significant sequence and structural similarity to B-box and ZZ domains. …”
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14073“…Third-generation dendrigraft poly-L-lysines was selected as the nanocarrier scaffold, which was modified by cell-penetrating peptides and gadolinium (Gd) chelates. DNA plasmids were loaded with these nanocarriers via electrostatic interaction. …”
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14074por González-Bártulos, Marta, Aceves-Luquero, Clara, Qualai, Jamal, Cussó, Olaf, Martínez, Mª Angeles, Fernández de Mattos, Silvia, Menéndez, Javier A., Villalonga, Priam, Costas, Miquel, Ribas, Xavi, Massaguer, Anna“…In summary, we report that, upon chelation of intracellular iron, the pro-oxidant activity of amine-pyrimidine-based iron complexes efficiently kills cancer and cancer stem-like cells, thus providing functional evidence for an efficient family of redox-directed anti-cancer metallodrugs.…”
Publicado 2015
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14075“…Each Cu(II) ion adopts a five-coordinate square-pyramidal coordination sphere where the basal N(2)O(2) plane is formed by two O atoms of the oxalate ligand and two N atoms of a bidentate chelating histamine molecule. The apical coordination site in compound (I) is occupied by a monodentate azide anion through one of its terminal N atoms. …”
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14076“…Extracted EPS and IPS showed higher antioxidant potential with significant DPPH radical scavenging activity, ABTS radical scavenging activity, reducing power and iron chelating activity. Antimicrobial activities of EPS and IPS varied among the tested bacterial strains. …”
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14077por Laan, Adrianus C., Santini, Costanza, Jennings, Laurence, de Jong, Marion, Bernsen, Monique R., Denkova, Antonia G.“…However, for this purpose, the micelles need to be radiolabeled, and almost all radiolabeling procedures published to date involve the conjugation of a chelating agent to the constituting polymer, which could actually affect their biodistribution. …”
Publicado 2016
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14078por Loaiza, Anitsi, Carretta, María D., Taubert, Anja, Hermosilla, Carlos, Hidalgo, María A., Burgos, Rafael A.“…The calcium response to all tested NEFAs showed an extracellular calcium dependence and only the LA response was significantly inhibited until the intracellular calcium was chelated. The EC(50) values for MA and LA were 125 μM and 37 μM, respectively, and the MA and LA effects were dependent on calcium release from the endoplasmic reticulum stores and on the L-type calcium channels. …”
Publicado 2016
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14079“…Genes predominantly expressed in the stem were enriched in not only pathways related to sugar, ether lipid, and amino acid metabolisms but also plant hormone signal transduction and circadian rhythm pathways, while the root-dominant genes were enriched in pathways related to lignin and cellulose syntheses, involved in plant-pathogen interactions, and potentially responsible for heavy metal chelating, and detoxification. Based on this transcriptome, 14,727 simple sequence repeats (SSRs) were identified, and 12,830 pairs of primers were developed for 2522 SSR-containing unigenes. …”
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14080“…In addition, it also chelates important dietary minerals and essential amino acids. …”
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