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  1. 1401
    “…Here, we demonstrate an alternate one-step spray-dry CLAMs process using pH-responsive chelation of calcium. The “Chelate CLAMs” process is an improvement over the patented process that controls ion availability based on pH-responsive solubility of the calcium salt. …”
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    Chelator Regulation of In Situ Calcium Availability to Enable Spray-Dry Microencapsulation in Cross-Linked Alginates
  2. 1402
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    Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic Viperinae Snake Venom Toxins
  3. 1403
    “…Considering direct mechanisms, chelators can bind zinc(II) that plays a catalytic role in enzyme activity. …”
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    The Role of Extracellular Proteases in Tumor Progression and the Development of Innovative Metal Ion Chelators That Inhibit Their Activity
  4. 1404
    “…The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the application for renewal of authorisation of manganese chelate of hydroxy analogue of methionine (Mintrex(®)Mn) for all animal species. …”
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    Assessment of the application for renewal of authorisation of manganese chelate of hydroxy analogue of methionine for all animal species
  5. 1405
    “…The effect of chelate cooperativity on the binding of several ditopic anions to two tetrathiourea macrocycles has been analysed in competitive solvent mixtures (H(2)O : DMSO 1 : 9 v/v). …”
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    Conformationally adaptable macrocyclic receptors for ditopic anions: analysis of chelate cooperativity in aqueous containing media
  6. 1406
    “…However, from a mechanistic standpoint, the thrombopoietin receptor is not expressed in Ewing sarcoma cells and we show that eltrombopag impairs DNA replication and causes DNA damage in Ewing sarcoma cells by chelating iron, a known “off-target” effect of the drug. …”
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    Eltrombopag inhibits the proliferation of Ewing sarcoma cells via iron chelation and impaired DNA replication
  7. 1407
    “…The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the application for renewal of authorisation of zinc chelate of hydroxy analogue of methionine (Mintrex(®)Zn) for all animal species. …”
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    Assessment of the application for renewal of authorisation of zinc chelate of hydroxy analogue of methionine for all animal species
  8. 1408
    por Mikhailov, Oleg V.
    Publicado 2021
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    Foreword from the Editor of Special Issue “Advanced Metal Chelate Complexes: Quantum-Chemical Consideration”
  9. 1409
    “…We present an alternative method capable of selectively preconcentrating Cu(2+) ions at the electrode surface using chelating polymer-wrapped multiwalled carbon nanotubes (MWCNTs). …”
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    In Situ Preconcentration and Quantification of Cu(2+) via Chelating Polymer-Wrapped Multiwalled Carbon Nanotubes
  10. 1410
    “…INTERVENTIONS: We treated the patient with iron chelator and followed up for 3 years. OUTCOMES: Iron chelator helped to reduce the serum ferritin and improve the condition of target organs, including skin, pancreas, liver as well as pituitary. …”
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    Iron chelators reverse organ damage in type 4B hereditary hemochromatosis: Case reports
  11. 1411
    “…The IPath(®) protein showed a significant chelating activity under in vitro conditions and biological activity. …”
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    Chimeric Protein IPath(®) with Chelating Activity Improves Atlantic Salmon’s Immunity against Infectious Diseases
  12. 1412
    “…The early initiation of a combined treatment including conventional chelation therapy and repeated MARS dialysis sessions allowed a rapid control of hemolysis, a progressive decrease of free copper overload, and clinical recompensation without liver transplantation.…”
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    Management of Acute Wilsonian Hepatitis with Severe Hemolysis: A Successful Combination of Chelation and MARS Dialysis
  13. 1413
    “…However, when administered orally, reduced absorption and bioavailability can occur due to chelation in the gastrointestinal tract (GIT) with multivalent metal cations acquired from diet, coadministered compounds (sucralfate, didanosine), or drug formulation. …”
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    Effects of Magnesium, Calcium, and Aluminum Chelation on Fluoroquinolone Absorption Rate and Bioavailability: A Computational Study
  14. 1414
    “…In the extensive field of metal ions, their interactions with nucleic acids, and their constituents, the main aim of this work is to develop a metal chelate suitable to recognize two molecules of an adenine nucleoside. …”
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    Dicopper(II)-EDTA Chelate as a Bicephalic Receptor Model for a Synthetic Adenine Nucleoside
  15. 1415
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    Synthesis of Red Cesium Lead Bromoiodide Nanocrystals Chelating Phenylated Phosphine Ligands with Enhanced Stability
  16. 1416
    “…Phelan-McDermid syndrome (PMS) is a multi-system disorder characterized by significant variability in clinical presentation. …”
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    Position effects of 22q13 rearrangements on candidate genes in Phelan-McDermid syndrome
  17. 1417
    “…Overall, this presents a novel and promising mechanism for therapeutic iron chelation.…”
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    The iron chelator, PBT434, modulates transcellular iron trafficking in brain microvascular endothelial cells
  18. 1418
    “…Under the optimal conditions, protein extraction rate was 64.89%, compared with alkaline extraction of 55.67%. The iron-chelating activity of peptides affected by ultrasound technology was further evaluated by iron-chelating rate, FTIR spectroscopy and LC-HRMS/MS. …”
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    Optimization of ultrasound assisted extraction of abalone viscera protein and its effect on the iron-chelating activity
  19. 1419
    “…[Image: see text] Fast ion-chelate dissociation rates and weak ion-chelate affinities are desired kinetic and thermodynamic features for imaging probes to allow reversible binding and to prevent deviation from basal ionic levels. …”
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    Fast Ion-Chelate Dissociation Rate for In Vivo MRI of Labile Zinc with Frequency-Specific Encodability
  20. 1420
    “…Herein, we describe the rational design and synthesis of two cyclic complexing agents (H(3)L1 and H(4)L2) bearing three and four hydroxamate chelating groups, respectively. The ligand structures allow us to take advantage of the macrocyclic effect; the H(4)L2 chelator contains an additional side amino group available for a possible further conjugation with a biomolecule. …”
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    Thermodynamic Stability and Speciation of Ga(III) and Zr(IV) Complexes with High-Denticity Hydroxamate Chelators
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