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  1. 14321
    “…In the first part of the present study, 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonic) acid (ABTS), reducing power assays, and metal ion chelating assays were used to investigate the in vitro antioxidant activities of Paeonia rockii. …”
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    In Vitro and In Vivo Antioxidant Activities of the Flowers and Leaves from Paeonia rockii and Identification of Their Antioxidant Constituents by UHPLC-ESI-HRMS(n) via Pre-Column DPPH Reaction
  2. 14322
    “…GSH depletion-dependent cell death was prevented by selective ferroptosis inhibitors (8 μM Fer-1 and 600 nM Lip-1), iron chelator DFO (80 μM), as well as autophagic inhibitors Baf-A1 (75 nM) and 3-MA (10 mM). …”
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    Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells
  3. 14323
    “…The cytotoxicity of CMS could be reduced with 10 mM N-acetyl-cysteine. Iron chelators, while ineffective against the polymyxins, could rescue all three bronchial epithelial cell lines treated with lethal PYO or CMS-PYO doses. …”
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    Interaction of Bacterial Phenazines with Colistimethate in Bronchial Epithelial Cells
  4. 14324
    “…Methods: Z(VEGFR2)-Bp(2) coupled to a NODAGA chelator was generated and radiolabeled with indium-111. …”
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    Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model
  5. 14325
    “…In patients with thalassemias it is mainly attributed to transfusional iron overload, and suboptimal iron chelation therapy. The main objectives of this survey were to provide data on the prevalence, demographic and clinical features of HPT in thalassemia major (TM) and intermedia (TI) patients living in different countries, and to assess its impact in clinical medical practice. …”
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    An ICET- A survey on hypoparathyroidism in patients with thalassaemia major and intermedia: a preliminary report
  6. 14326
    “…The aim of our study was to identify the effects of mangafodipir, a manganese chelate and SOD-mimetic, on suppression of apoptosis in granulosa cells and primordial follicle activation induced by anticancer drugs. …”
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    Protective effects of mangafodipir against chemotherapy-induced ovarian damage in mice
  7. 14327
    “…The overexpressed enzyme was purified from the cell-free extract of isopropyl thio-β-D-galactoside IPTG-induced E. coli M15 (pQE-EcPepQ) cells by nickel-chelate chromatography. The molecular mass of EcPepQ was determined to be about 57 kDa by 12% sodium dodecyl sulfate–polyacrylamide gel electrophoresis and the result of size-exclusion chromatography demonstrated that the enzyme was mainly present in 25 mM Tris–HCl buffer (pH 8.0) as a dimeric form. …”
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    High-level expression and molecular characterization of a recombinant prolidase from Escherichia coli NovaBlue
  8. 14328
    “…In contrast, unstimulated VSMCs incubated with an intracellular calcium chelator, BAPTA-AM, showed reduced cell adhesion to FN as well the expected decrease in [Ca(2+)](i). …”
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    A Calcium Mediated Mechanism Coordinating Vascular Smooth Muscle Cell Adhesion During KCl Activation
  9. 14329
    “…Our results indicated that Aloe vera fermentation could markedly reduce the DPPH (56.12%), O(2·−) (93.5%), (·)OH (76.12%), Fe(2+) chelation (82%), and oxygen-reduction activity (0.28 μg/ml) and significantly inhibited the growth of pathogens S. typhimurium ATCC 13311 (inhibition zone diameter: 14 mm), S. enteritidis ATCC13076 (IZD: 13 mm), S. flexneri ATCC 12022 (IZD: 18 mm), E. coli 44102 (IZD: 10 mm), L. monocytogenes ATCC 19111 (IZD: 18 mm), S. dysenteriae 301 (IZD: 20 mm), S. aureus COWAN1 (IZD: 19 mm), and P. acnes ATCC 11827 (IZD: 25 mm) in vitro. …”
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    Evaluation of the Treatment Effect of Aloe vera Fermentation in Burn Injury Healing Using a Rat Model
  10. 14330
    “…Conclusion: The formation of the complexes between the DOX and ZnO nanoparticles at the chelating sites of the quinone and the phenolic oxygen molecules of DOX, lead to more sustained drug release and enhanced chemotherapy effectiveness by increasing the intracellular concentration of DOX.…”
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    Chemotherapy of Breast Cancer Cells Using Novel pH-Responsive Cellulose-Based Nanocomposites
  11. 14331
    “…METHODS: Cetuximab (C225) was conjugated to a bifunctional chelator, p-isothiocyanatobenzyl-1,4,7-triazacyclononane-1,4,7-triacetic acid (NOTA), and further radiolabeled with copper-64 for PET imaging. (64)Cu-NOTA-IgG and Cy5.5-C225 were also synthesized as control probes. …”
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    Synthesis and evaluation of (64)Cu-radiolabeled NOTA-cetuximab ((64)Cu-NOTA-C225) for immuno-PET imaging of EGFR expression
  12. 14332
    por Kamal, Palwasha, Sharma, Sona
    Publicado 2019
    “…The mechanism of action hypothesized has been the medications ability to chelate magnesium which in turn affects the glucose transport via GLUT 4 receptor and gluconeogenesis causing insulin resistance.…”
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    SUN-187 Dolutegravir Causing Diabetes
  13. 14333
    “…Nicotianamine (NA) is a ubiquitous chelator of metal cations and is responsible for metal homeostasis. …”
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    Nicotianamine Synthesis by OsNAS3 Is Important for Mitigating Iron Excess Stress in Rice
  14. 14334
    “…The present work aimed to investigate the role of Paneth cells in small intestinal injury during acute necrotizing pancreatitis (ANP) using rat models established by injection of dithizone, a metal chelator of zinc with the ability to selectively ablate Paneth cells. …”
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    Paneth cell ablation increases the small intestinal injury during acute necrotizing pancreatitis in rats
  15. 14335
    “…Lanthanide ions when complexed by polyamino-polycarboxylate chelators form a class of compounds of paramount importance in several research and technological areas, particularly in the fields of magnetic resonance and molecular magnetism. …”
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    Covalency and magnetic anisotropy in lanthanide single molecule magnets: the DyDOTA archetype
  16. 14336
    “…After the orthotopic GL261 cells injection in the right striatum of C57BL6 mice and the intranasal (IN) GlaB/mPEG(5kDa)-Cholane treatment, the tumor growth was evaluated. …”
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    (1)H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma
  17. 14337
    “…Here, we evaluated the feasibility of a pretargeting strategy for multimodal imaging in colorectal cancer using an anti-carcinoembryonic antigen (CEA) x anti-histamine-succinyl-glycine (HSG) bispecific antibody (TF2) in conjunction with the dual-labeled diHSG peptide (RDC018), using both a fluorophore for near-infrared fluorescence imaging and a chelator for radiolabeling. METHODS: Nude mice with subcutaneous (s.c) CEA-expressing LS174T human colonic tumors and CEA-negative control tumors were injected with TF2. …”
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    A pretargeted multimodal approach for image-guided resection in a xenograft model of colorectal cancer
  18. 14338
    “…Then, the remaining nitrogen atoms of the Au-Apt-TPE could effectively chelate with Zn(2+) ions (Au-Apt-TPE@Zn) for monitoring early stage apoptotic cells. …”
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    Dual-Targeted Gold Nanoprism for Recognition of Early Apoptosis, Dual-Model Imaging and Precise Cancer Photothermal Therapy
  19. 14339
    “…METHODS: In this study, we reviewed the demographic and clinical characteristics (e.g., age, sex, duration of blood transfusion and chelating therapy, and vitamin supplementation) and serum biomarker levels (e.g., iron accumulation, bone metabolism, liver, kidney, and thyroid function markers) of 32 patients that received regular blood transfusion at a single center in southern China with the aim of stratifying the risk of severe complications such as osteopenia, endocrinopathies, and multi-organ failures. …”
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    Evaluation of the vitamin D and biomedical statuses of young children with β-thalassemia major at a single center in southern China
  20. 14340
    “…Rice acquires Fe from the soil via Strategy I–related system (ferrous ion uptake by OsIRT1) and Strategy II system (ferric ion uptake by chelation). However, rice plants have a weak ability in Fe(III) reduction and phytosiderophore secretion. …”
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    Enhancement of Iron Acquisition in Rice by the Mugineic Acid Synthase Gene With Ferric Iron Reductase Gene and OsIRO2 Confers Tolerance in Submerged and Nonsubmerged Calcareous Soils
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