“…A strong correlation was observed between ALT and 1-hour plasma glucose value during OGTT in the total group of 36 patients . Compliance to iron chelation therapy was poor in β-TDT patients with H-NGT. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: We investigated class IIa HDAC4 and HDAC5 and H3K9/H3K27 histone acetylation in tx-j mouse livers compared with C3HeB/FeJ (C3H) control in response to 3 treatments: 60% kcal fat diet, D-penicillamine (copper chelator), and choline (methyl group donor). Experiments with copper-loaded hepatoma G2 cells were conducted to validate in vivo studies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The patients were divided into 3 different groups: 53 patients received gadolinium chelate (Dotarem®)–buttermilk mixture (GBM) in a dilution of 1:40 as an oral contrast agent; 44 patients received LumiVision® water mixture (LWM) in a dilution of 1:1 and 49 patients received LumiVision® (L) undiluted. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We applied UHPLC-HRMS for chromatographic analysis of rose wastewaters, studied their metal-chelating and Fe(III)-reducing ability, and performed MTT assay for the evaluation of cytotoxic potential against three tumorigenic (HEPG2—hepatocellular adenocarcinoma, A-375—malignant melanoma, A-431—non-melanoma epidermoid squamous skin carcinoma) and one non-tumorigenic human cell lines (HaCaT—immortalized keratinocytes). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The hydroalcoholic extract of the L. shawii also demonstrated the best chelating activity at 21.84 mg/gm EDTA equivalents. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The compound exhibited remarkable anti-oxidant activities, recording the IC(50) value of 19.65 ± 5.7 µg/mL in DPPH, IC(50) of 15.49 ± 4.8 against NO free radicals, the IC(50) value of 19.65 ± 5.22 µg/mL against scavenging ability, and IC(50) value of 19.38 ± 7.11 µg/mL for iron chelation capacity and the cytotoxic activities against PC3 cell lines were recorded with IC(50) values of 35.81 ± 4.2 µg/mL after 24 h, 23.29 ± 3.8 µg/mL at 48 h, and 16.25 ± 6.5 µg/mL after 72 h. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Calcium handling differs from other solutes because of increases caused in citrate concentration and subsequent effects on calcium chelation. In citrate CVVH, CathPR in dysfunctional catheters should be limited in time, with intensive follow-up. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The surface molecular diversity of L‐EVs include (i) bona fide plasma membrane anchored proteins (cluster of differentiation, transporters, receptors and GPI anchored proteins implicated in cell‐cell and cell‐ECM interactions); and (ii) membrane surface‐associated proteins (that are released by divalent ion chelator EDTA) implicated in actin cytoskeleton regulation, junction organization, glycolysis and platelet activation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: Iron overload contributes to the process of endothelial cell calcification by inducing apoptosis and ferroptosis. Iron chelators and ferroptosis inhibitors alleviate endothelial cell apoptosis, ferroptosis, and calcification induced by iron overload.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, the short half-life of (68)Ga (68 min) creates problems with manufacture and delivery. (18)F (half-life, 110 min) labeling would result in a more practical large-scale production, and a cold-kit formulation would improve the spontaneous availability. The NOTA chelator ligand FAPI-74 can be labeled with both (18)F-AlF and (68)Ga. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…At present, the main therapies for ß-thalassemia patients include regular blood transfusion and iron chelation, associating with a number of limitations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The free radical scavenging activities, cytotoxicity, ferric-reducing antioxidant power (FRAP), metal chelating activities, total phenolic compound (TPC) contents, and total flavonoid (TF) contents of Tri-TT extract were investigated, and qualitative analysis of the chemical composition of Tri-TT extract was performed by LC-QTOF-MS. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Combinations of NaOCl with different chelating agents were ineffective in terms of antimicrobial, but it could potentially increase the risk of irrigant extrusion. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Mechanistically, extracellular vesicles (EVs) derived from PKM2-activated T lymphocytes elevated macrophage iron accumulation, lipid peroxidation, and migration in vitro, while macrophages treated with EVs from PKM2-null T lymphocytes or pretreated with the lipid peroxidation inhibitors ferrostatin-1 (Fer-1), liproxstatin-1 (Lip-1), or the iron chelating agent deferoxamine mesylate (DFOM) reversed these effects. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, disulfiram also acts as a copper chelator that was shown to block lysyl oxidase activity, an enzyme involved in formation of collagen crosslinks. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Two years field experiment was conducted to evaluate the effect of Zn-biochemical (nitrogen “N”, phosphorus “P”, and potassium “K”) co-fertilization on yield and yield components, physico-chemical characteristics, and nutrient recovery and surplus as well as farm profitability of four rice (Oryza sativa L.) cultivars treated with two Zn levels (no Zn application, and 600 mg chelated Zn L(−1) as a foliar application) and six fertilization regimes (no fertilizers application, biofertilizers, 25% NPK plus biofertilizers, 50% NPK plus biofertilizers, 75% NPK plus biofertilizers, and 100% NPK). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…While alkyl substituents in general exhibit electron-donating properties, variation in the nature and substitution-position of the alkyl group in the N^N chelate leads to different effects in the photophysical properties of the [Cu(P^P)(N^N)][PF(6)] complexes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The first solvation shell of [Fe(tpen)](2+) consists of ACN molecules located in the grooves defined by the chelating coordination motif of the tpen ligand. Upon the LS → HS change of states, the solvation number of the complex is found to increase from ≈9.2 to ≈11.9 and an inner solvation shell is formed. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Single crystal structures of [Cu(POP)(1)][PF(6)], [Cu(xantphos)(1)][PF(6)], [Cu(xantphos)(2)][PF(6)], [Cu(POP)(3)][PF(6)]·CH(2)Cl(2), and [Cu(xantphos)(4)][PF(6)] confirm chelating N^S and P^P ligands, and distorted tetrahedral copper(i) centres. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Plants have evolved two distinct mechanisms to solubilize and transport Fe to acclimate to Fe deficiency, including reduction-based strategy (strategy I) and chelation-based strategy (strategy II), and maize uses strategy II. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso