“…The diverse effects of tannins on the reproductive system as a result of their potential metal ion chelation, protein precipitation, and biological antioxidant abilities have been identified. …”
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“…To cope with Al stress, the SENSITIVE TO PROTON RHIZOTOXICITY1 (STOP1) transcription factor induces AL-ACTIVATED MALATE TRANSPORTER1 (ALMT1), a malate-exuding transporter as a strategy to chelate the toxic ions in the rhizosphere. Here, we uncoupled the Al signalling pathway that controls STOP1 from Al toxicity using wild type (WT) and two stop1 mutants carrying the pALMT1:GUS construct with an agar powder naturally containing low amounts of phosphate, iron (Fe), and Al. …”
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“…METHODS: Various new PSMA ligands were synthesized using solid-phase chemistry and provided with a DOTA chelator for (111)In labeling and the fluorophore/photosensitizer IRDye700DX. …”
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“…In addition, it showed a selective accumulation in brain tumor tissues, exhibiting longer retention within the tumor, which allows performing imaging acquisition over longer time frames (≥2.5 h) as opposed to Gd chelates. Finally, we observed high stability of the radicals in biological media, on the order of hours instead of minutes, characteristic of the isolated radicals. …”
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“…Cultured cells were incubated with lipopolysaccharide (LPS) to mimic inflammation as well as in the presence of 4μ8C (IRE1 inhibitor III) to block endoplasmic reticulum (ER) stress and BAPTA-AM, a calcium chelator. RESULTS: LPS reduced the expression of nuclear IL-33 in a time-limited manner and induced ER stress. …”
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“…The prepared films exhibited good antimicrobial activity against both Gram-positive and Gram-negative bacteria with mild antioxidant and metal chelating activity, and significant inhibition of biofilm formation with a strong link with emitted color and the concentration of the composites. …”
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“…X-ray and DFT studies showed the free proligands to exist in the N–H,N–H tautomeric form and that in [Zn(HL(1))(2)(MeOH)(2)], zinc is six-coordinated by the N,O-chelated (HL(1)) ligand and other two oxygen atoms of coordinated methanol molecules, while [Cu(HL(1))(2)] adopts a square planar geometry with the two (HL(1)) ligands in anti-conformation. …”
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“…The results highlight the efficient chelation of Pb(2+) ions by the grafted NH(2) groups and the potential of talc-like amino-functionalized magnesium phyllosilicate for application in electrochemical sensors.…”
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“…Study participants expressed a desire for ‘cure’ from thalassemia including transfusion independence, chelation reduction and improved quality of life as motivators for considering GT. …”
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“…NADES-B (protonated by HCl L-proline-xylitol 5:1) was the only extractant from the studied solvents that isolated a specific fraction without chelating activity. Reline extract exhibited the highest acetylcholinesterase inhibition compared to NADES-B and NADES-C (protonated by H(2)SO(4) L-proline-xylitol 5:1) extracts, which showed no inhibition. …”
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“…METHODS: Here a sandwich TRFIA was optimized and established: Anti-S100A8/LRG1 caputre antibodies immobilized on 96-well plates captured S100A8/LRG1, and then banded together with the anti-S100A8/LRG1 detection antibodies labeled with Europium(III) (Eu(3+))/samarium(III) (Sm(3+)) chelates. Finally time resolved fluorometry measured the fluorescence intensity. …”
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“…CONCLUSIONS: Based on the findings of this in vitro study, a desirable biological growth factor‐mediated effect may be gained when conditioning dentine by milder acidic or chelating agents such as citric acid and EDTA. The results must be interpreted in the context that the potential of the applied materials inducing a desirable biological response in DPSCs is only one consideration amongst other important ones in a clinical setting. …”
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“…While PSMA-617 carries the DOTA moiety as the complexing agent, the chelator macropa as a macrocyclic alternative provides even more beneficial properties regarding labeling and complex stability in vivo. …”
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“…We have studied activation of the methyl C–H bonds in the cyclopentadienyl ligands of half-sandwich Rh(iii) complexes [η(5)-Cp(X)Rh(N,N′)Cl](+) by observing the dependence of sequential H/D exchange on variations in Cp(X) = Cp* (complexes 1 and 2), Me(4)PhCp (Cp(XPh), 3) or Me(4)PhPhCp (Cp(XPhPh), 4), and chelated ligand N,N′ (bpy, 1; phen, 2–4). H/D exchange was fastest in d(4)-MeOD (t(1/2) = 10 min, 37 °C, complex 1), no H/D exchange was observed in DMSO/D(2)O, and d(4)-MeOD enhanced the rate in CD(3)CN. …”
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“…In vitro experiments revealed that the expression of BARX1, GFRA3, and KHDRBS2 was upregulated after cuproptosis was induced by elesclomol–CuCL(2), whereas the upregulation was suppressed on pretreatment with tetrathiomolybdate (TTM), a chelator of copper. Further, the cell proliferation assay revealed that the BARX1 and GFRA3 deficiency facilities the cuproptosis induced by elesclomol–CuCL(2). …”
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“…[Image: see text] Metallodithiolene complexes of the type [(R(2)C(2)S(2))M(η(2)-tpbz)] [R = CN, Ph, or p-anisyl; M = Ni(2+), Pd(2+), or Pt(2+); tpbz = 1,2,4,5-tetrakis(diphenylphosphino)benzene] chelate transition metals ions to form trimetallic arrays [[(R(2)C(2)S(2))M(tpbz)](2)M′](n+), where M′ is square planar Pt(2+), tetrahedral Cu(+), Ag(+), or Au(+), or octahedral {ReBr(CO)}/{Re(CO)(2)}(+). …”
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“…A remarkable in-vitro anti-oxidant potential of CDPDP was recorded with the IC(50) value of 30.06 ± 5.11 μg/ml in DPPH, IC(50) of 18.98 ± 2.91 against NO free radicals, the IC(50) value of 27.15 ± 3.12 against scavenging ability and IC(50) value of 28.40 ± 3.14 μg/ml for iron chelation capacity. Downregulation of pro-inflammatory mediators (NO and MDA), suppressed levels of pro-inflammatory cytokines (TNF-α, IL-6, IL-Iβ) and upregulation of expressions of anti-oxidant enzymes (GSH, catalase, and GST) unveiled its anti-inflammatory potential. …”
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“…This work focuses on a the neurotensin peptide analogue NT-20.3 conjugated to the chelator NOTA for radiolabeling for use in noninvasive positron emission tomography (PET). …”
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“…Further, the elevation of citrate and malate concentration along with the expression of citrate synthase (GmCs) and malate synthase (GmMs) caused by TH suggest improved chelation of Fe in Fe‐deficient plants. Results also suggest that TH has a role in triggering antioxidant defence by increasing the activity of glutathione reductase (GR) along with elevated S‐metabolites (glutathione and methionine) to stabilize redox status under Fe‐deficiency. …”
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“…(Asteraceae) herb plant separately and in combination with cobalt (II) chloride (CoCl(2)) chelate compounds on the course of metabolic processes in the rumen, methane concentration, and biochemical blood parameters in bulls. …”
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