“…MRI was performed on 21 patients with BTM who were receiving blood transfusions and chelation therapy. The control group (n=11) included healthy volunteers. …”
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“…Treatment of COMMD3-depleted cells with the copper chelator, tetrathiomolybdate, significantly reduced invasive spheroid growth via induction of apoptosis. …”
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“…The highest antioxidant activity in terms of Trolox equivalent antioxidant capacity (0.23–2.75 mM), DPPH (33.3%–64.8%), and hydroxyl (33.7%–63.2%) radical scavenging activities, chelation of iron (33.2%–62.5%) and copper (30.2%–50.5%) metals, and total antioxidant activity (0.65–0.85) was obtained for H‐Pep followed by H‐Pan and H‐Tri samples. …”
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“…The agent can be site-specifically labeled with a beta-emitting radionuclide (177)Lu using a DOTA chelator. The goals of this study were to test the hypotheses that a targeted radionuclide therapy using [(177)Lu]Lu-ABY-027 could extend the survival of mice with HER2-expressing human xenografts and that co-treatment with [(177)Lu]Lu-ABY-027 and the HER2-targeting antibody trastuzumab could enhance this effect. …”
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“…Each nanoparticle was produced by applying highly efficient “green” synthesis techniques, which are free of fossil derivatives and use nitrate, chlorate and sulfonate salts as starting materials and whey as chelating agents. The two “green” nanomaterials differ in size distribution, with ZnO-NP-45 consisting of particles ranging from 30 nm to 60 nm and ZnO-NP-76 from 60 nm to 92 nm. …”
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“…In addition, phytic acid chelates positively charged minerals making them unavailable in the diet. …”
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“…BACKGROUND: With adequate blood transfusion and iron chelation, thalassemia patients have a longer life expectancy and experience long-term metabolic complications, including osteoporosis, fractures, and bone pain. …”
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“…METHODS: A total of 15 Holstein heifer calves (6-week-old, 82.71 ± 1.35, mean ± standard error) were randomly designed into three groups (five each): no extra Mn supplemented (CON), 20 mg Mn/kg (dry matter basis) in the form of chelates of lysine and glutamic acid in a mixture of 1:1 (LGM), and 20 mg Mn/kg (dry matter basis) in the form of MnSO(4). …”
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“…[Image: see text] Treatment of the bis(chelate) complexes trans-[M(κ(2)-2-C(6)F(4)PPh(2))(2)] (trans-1M; M = Ni, Pt) and cis-[Pt(κ(2)-2-C(6)F(4)PPh(2))(2)] (cis-1Pt) with equimolar amounts or excess of PMe(3) solution gave complexes of the type [(Me(3)P)(x)M(2-C(6)F(4)PPh(2))(2)] (x = 2: 2M(a), 2M(b)x = 1: 3M(a), 3M(b); M = Ni, Pt). …”
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“…In this study, we have used citrus lemon juice consisting of a variety of chemical compounds having the properties of a stabilizing agent, capping agent and chelating agent. Moreover, the presence of several acidic chemical compounds in citrus lemon juice changed the pH of the growth solution and consequently we observed surface modified and structural changes that were found to be very effective for the development of energy conversion and energy storage systems. …”
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“…Cetuximab was conjugated with (47)Sc using the bifunctional chelating agent DTPA. Radiochemical purity was determined using instant thin-layer chromatography. …”
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“…BACKGROUND: A family of BF(2)-chelated tetraaryl-azadipyrromethenes was developed as non-porphyrin photosensitizers for photodynamic therapy. …”
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“…Intracellular calcium chelator Bapta, low extracellular calcium and the Ca(2+) channels blocker La(3+) reduced the ATP-stimulated, but not the basal secretion. …”
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“…The Rapid escalation of chelation therapy precipitated SD in 11 patients with Wilson’s disease. …”
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“…Conclusions: This is the first demonstration of the use of trans-cyclooctene-tetrazine click-to-release chemistry to release a radioactive chelator from a mAb in mice to increase tumor-to-blood ratios. …”
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“…FAP-targeting antibody 28H1 and irrelevant control antibody DP47GS were conjugated to the photosensitizer IRDye700DX (700DX) and the chelator diethylenetriaminepentaacetic acid. In vitro binding and cytotoxicity were evaluated using the fibroblast cell-line NIH-3T3 stably transfected with FAP. …”
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“…Single crystal X-ray structures of 1 and 3 reveal that Ni(ii) is involved in π-back bonding with flavonolate (fla(−)), as evident from enhancement in C[double bond, length as m-dash]O bond length upon coordination [H(fla), 1.232(3); 1, 1.245(7); 3, 1.262(8) Å]. More asymmetric chelation of fla(−) in 3 than in 1 [Δd = (Ni–O(carbonyl) − Ni–O(enolate)): 1, 0.126; 3, 0.182 Å] corresponds to lower π-delocalization in 3 with electron-releasing N-Et substituent. …”
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“…Deletion of recA in JH2010 resulted in higher in vitro supernatant cytotoxicity compared to that from JH2016ΔrecA, and the addition of the chelator ethylenediaminetetraacetic acid (EDTA) and various metal cations to the growth medium exacerbated the difference in cytotoxicity exhibited by the two deletion strains. …”
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“…Though the dual linker approach using the instillation of MV-MVK or MVK-MVK between exendin-4 and the radiometal chelator did not significantly outperform the single cleavable linker MVK, further structural optimization or the combination of different cleavable linkers could be a stepping stone in reducing radiation-induced nephrotoxicity. …”
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“…Despite the color difference, red and yellow 2·H(2)O have the same structure as determined by single-crystal and X-ray powder diffraction, namely, an octahedral ligand array with a chelating organoamide, pyridine and chloride ligands in the equatorial plane, and axial hydroxido ligands. …”
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