“…Chromomycin A3 (Chro) is capable of forming a stable dimeric complex via chelation with Ni(II), Fe(II) and Co(II). According to the circular dichroism study, the dimer conformations are significantly different among the Fe(II)-, Co(II)-, and Ni(II)-containing dimeric Chro complexes; however, the dimer conformations were preserved at high temperatures. …”
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“…The adsorptive mechanism of GIMN1.004(T) for cadmium depended on the action of the amide,carboxy and phosphate of cell surface and producing low-molecular-weight (LMW ) organic acids to complex or chelated Cd(2+).Therefore, the strain GIMN1.004(T) represented a new cadmium resistance species, which was tentatively named as Burkholderia dabaoshanensis sp. nov. …”
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“…Biotinylated and europium(III) chelate-labeled versions of this antigen were used to set up one- and two-step time-resolved fluorometric double antigen sandwich assays. …”
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“…Several potential antioxidant activities, including radical-scavenging ability (RSA), ferrous ion chelating (FIC) and ferric ion reducing antioxidant power (FRAP), were evaluated. …”
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“…The experimental results further revealed that A. precatorius extracts showed strong antiradical properties, capable to chelate Fe(2+) and possess good inhibition ability of lipid peroxidation. …”
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“…The proteins collected in the insoluble fraction of cell lysates, solubilized with sarkosyl, were purified by Ni-chelating chromatography. Final yield was 2.0, 3.0, or 3.5 mg/l of cell culture for mOCTN3, hOCTN1, or hOCTN2R2K. …”
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“…Treatment with the Ca(2+) chelator BAPTA (5 mM) showed that the nucleolar localization of CBP4a is Ca(2+)-dependent. …”
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“…Although this is the largest and only randomized study in patients with LV decompensation, further prospective evaluation is needed to identify optimal chelation management in these high-risk patients.…”
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“…MATERIALS AND METHODS: To assess the oralglucose tolerance (OGT) and 72-h continuous glucose concentration by the continuous glucose monitoring system (CGMS) and calculate homeostatic model assessment (HOMA), and the quantitative insulin sensitivity check index (QUICKI) was conducted in 16 adolescents with BTM who were receiving regular blood transfusions every 2-4 weeks and iron-chelation therapy since early childhood. RESULTS: Sixteen adolescents with BTM (age: 19.75 ± 3 years) were investigated. …”
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“…The targeting vectors C595 and PAI2 were labeled with the alpha emitting radioisotope (213)Bi using the chelators cDTPA and CHX-A″ to form the alpha-conjugates (AC). …”
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“…To minimize this problem, we developed a novel (99m)Tc-labeled annexin A5 using a bis(hydroxamamide) derivative [C(3)(BHam)(2)] as a bifunctional chelating agent, and evaluated its usefulness as an imaging agent for detecting apoptosis. …”
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“…Silencing of AKR1C2 mRNA or inhibition of AKR1C2 by 5β-cholanic acid resulted in a decrease in the survival of cells following cisplatin exposure. …”
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“…Ca(+2) activated all the miswak α-amylases, while Ni(2+), Co(+2) and Zn(+2) activated or inhibited some of these enzymes. The metal chelators, EDTA, sodium citrate and sodium oxalate had inhibitory effects on miswak α-amylases. …”
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“…Co-loading of smooth muscle strips with the slow Ca(2+) chelator EGTA-AM (10 mM) confirmed that Ca(2+) sparklets are restricted to the cell membrane. …”
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“…In these cells, resveratrol increased calcium levels, and depletion of intracellular calcium by a calcium chelator, BAPTA, attenuated resveratrol-enhanced TG2 immunoreactivity. …”
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“…In HUVECs, PV increased NO formation, which was greatly attenuated by NOS inhibitors (L-NAME and L-NMMA) and by removing extracellular Ca(2+) and chelating intracellular Ca(2+) with BAPTA-AM. In addition, PV promoted eNOS phosphorylation, Nrf2 degradation, and HO-1 protein expression according to a Western blot analysis. …”
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“…Cholesterol levels were increased or decreased utilizing cholesterol-chelating methyl-β-cyclodextrin (MβCD), which can either extract membrane cholesterol or add exogenous membrane cholesterol depending on whether MβCD is preloaded with cholesterol. …”
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“…The intracellular Ca(2+) chelator BAPTA-AM or the mitochondrial Ca(2+) uniporter inhibitor RU360 blocked the ATP-induced mitochondrial depolarization in the presence of cyanidin-3-glucoside. …”
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“…The aim of this study was the evaluation of an anti-IGF-1R affibody molecule labeled with technetium-99m using cysteine-containing peptide-based chelator GGGC at C-terminus. Z(IGF1R:4551)-GGGC was efficiently and stably labeled with technetium-99m (radiochemical yield 97 ± 3 %). (99m)Tc-Z(IGF1R:4551)-GGGC demonstrated specific binding to IGF-1R-expressing DU-145 (prostate cancer) and MCF-7 (breast cancer) cell lines and slow internalization in vitro. …”
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“…To target strains with high iron sequestration mechanisms, a strong iron chelator 2,2-dipyridyl was supplemented to the agar media. …”
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