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14601por Ferrarini, Andrea, Fracasso, Alessandra, Spini, Giulia, Fornasier, Flavio, Taskin, Eren, Fontanella, Maria Chiara, Beone, Gian Maria, Amaducci, Stefano, Puglisi, Edoardo“…Positive evidence of the soil-microbe-plant interactions occurring when bioaugmentation with PGPR is associated with deep-rooting perennial crops makes this combination preferable over the one with chelating agents. Such knowledge might help to yield better bioaugmented bioremediation results in contaminated sites.…”
Publicado 2021
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14602“…The separate addition of an exogenous electron shuttle (anthraquinone-2,6-disulfonate), a metal chelator (nitrilotriacetic acid), and 75% spent cell-free supernatant did not stimulate growth with or without the barrier. …”
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14603por Mayneris-Perxachs, Jordi, Cardellini, Marina, Hoyles, Lesley, Latorre, Jèssica, Davato, Francesca, Moreno-Navarrete, José Maria, Arnoriaga-Rodríguez, María, Serino, Matteo, Abbott, James, Barton, Richard H., Puig, Josep, Fernández-Real, Xavier, Ricart, Wifredo, Tomlinson, Christopher, Woodbridge, Mark, Gentileschi, Paolo, Butcher, Sarah A., Holmes, Elaine, Nicholson, Jeremy K., Pérez-Brocal, Vicente, Moya, Andrés, Clain, Donald Mc, Burcelin, Rémy, Dumas, Marc-Emmanuel, Federici, Massimo, Fernández-Real, José-Manuel“…In addition, several bacterial functions related to iron metabolism (transport, chelation, heme and siderophore biosynthesis) and NAFLD (fatty acid and glutathione biosynthesis) were also associated with the host serum ferritin levels. …”
Publicado 2021
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14604por Dewulf, Jonatan, Vangestel, Christel, Verhoeven, Yannick, De Waele, Jorrit, Zwaenepoel, Karen, van Dam, Peter A., Elvas, Filipe, Van den Wyngaert, Tim“…Experimental design: Anti-human RANKL mAbs (AMG161 and AMG162) were radiolabeled with (89)Zr using the bifunctional chelator DFO in high yield, purity and with intact binding affinity. …”
Publicado 2021
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14605“…This will contribute to minimize the environmental impacts caused by the use of P and Fe fertilizers (Fe chelates) in agriculture and to adjust the costs for farmers, due to the high prices and/or scarcity of Fe and P fertilizers. …”
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14606“…We now report that by changing the potassium chelator from crypt to 18-crown-6 (18-c-6), the [Ln(NR(2))(3)](1−) anions can be isolated not only for Ln = Gd, Tb, Dy, and Tm, but also for Ho, Er, and Y. …”
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14607por Rosselli, Marinella, Cometti, Barbara P. S., Leeners, Brigitte, Szutkowska, Marta Ewa, Jackson, Edwin K., Dubey, Raghvendra K.“…Moreover, BAPTA-AM (intracellular-Ca(2+) chelator) abrogated the effects of E2, but not genistein, on cAMP suggesting differential involvement of Ca(2+). …”
Publicado 2021
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14608por Chigoho, Dora Mugoli, Lecocq, Quentin, Awad, Robin Maximilian, Breckpot, Karine, Devoogdt, Nick, Keyaerts, Marleen, Caveliers, Vicky, Xavier, Catarina, Bridoux, Jessica“…The cysteine-tagged nanobody was site-specifically conjugated with a maleimide (mal)-NOTA chelator and radiolabeling was tested at different nanobody concentrations and temperatures. …”
Publicado 2021
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14609por Wang, Xiaoming, Guo, Shiwei, Li, Zhiqian, Luo, Qiang, Dai, Yan, Zhang, Hu, Ye, Yun, Gong, Qiyong, Luo, Kui“…Currently, paramagnetic nitroxides (such as (2,2,5,5-tetramethylpyrrolidine-1-oxyl, PROXYL), (2,2,6,6-tetramethylpiperidine-1-oxide, TEMPO), etc.) are being extensively studied because their good stability and imaging mechanism are similar to metal-based contrast agents (such as Gd(3+) chelate-based clinical CAs). However, a lower relaxivity and rapid in vivo metabolism of nitroxides remain to be addressed. …”
Publicado 2021
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14610por Ciaffaglione, Valeria, Waghorn, Philip A., Exner, Rüdiger M., Cortezon-Tamarit, Fernando, Godfrey, Samuel P., Sarpaki, Sophia, Quilter, Helena, Dondi, Ruggero, Ge, Haobo, Kociok-Kohn, Gabriele, Botchway, Stanley W., Eggleston, Ian M., Dilworth, Jonathan R., Pascu, Sofia I.“…Depending on the metal, probe conjugates of relevance for single photon emission computed tomography (SPECT) or positron emission tomography (PET) probes have been designed and tested hereby, using TPP and related functional free base porphyrins as the bifunctional chelator synthetic scaffold and (111)In[In] or (68)Ga[Ga], respectively, as the central metal ions. …”
Publicado 2021
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14611por Zhang, Junqiu, Xu, Liwei, Jiang, Hongtao, Xu, Chuanlai, Liu, Wenjing, Wu, Ting, Kuang, Hua“…The resulting solution was neutralized using NaOH at pH 7 and the free metal ions in the solution were chelated with EDTA for the immunoassay detection. An indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) method was developed for Cu ion analysis. …”
Publicado 2021
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14612por Deyev, Sergey M., Xu, Tianqi, Liu, Yongsheng, Schulga, Alexey, Konovalova, Elena, Garousi, Javad, Rinne, Sara S., Larkina, Maria, Ding, Haozhong, Gräslund, Torbjörn, Orlova, Anna, Tolmachev, Vladimir, Vorobyeva, Anzhelika“…Two variants, having an N- or C-terminal cysteine, were produced, site-specifically conjugated to a DOTA chelator and labeled with cobalt-57, gallium-68 or indium-111. …”
Publicado 2021
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14613“…The eATP production could be suppressed by the Ca(2+) chelator EGTA or abolished by the channel blocker La(3+), ROS scavenger vitamin C and NADPH oxidase inhibitor diphenyleneiodonium chloride (DPI). …”
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14614por Lorinczova, Helena Tiekou, Begum, Gulshanara, Renshaw, Derek, Zariwala, Mohammed Gulrez“…Curcumin is a potent antioxidant and has also been shown to exhibit iron chelation in-vitro, although it is not established whether these effects are retained in-vivo. …”
Publicado 2021
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14615por Lindner, Thomas, Altmann, Annette, Giesel, Frederik, Kratochwil, Clemens, Kleist, Christian, Krämer, Susanne, Mier, Walter, Cardinale, Jens, Kauczor, Hans-Ulrich, Jäger, Dirk, Debus, Jürgen, Haberkorn, Uwe“…They are characterized by overexpression of the fibroblast activation protein (FAP), a serine protease which was already proven as attractive target for chelator-based theranostics. Unfortunately, the value of gallium-68 labeled tracers is limited by their batch size and the short nuclide half-life. …”
Publicado 2021
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14616por Lee, Yu-Ran, Joo, Hee-Kyoung, Lee, Eun-Ok, Kim, Sungmin, Jin, Hao, Choi, Yeon-Hee, Kim, Cuk-Seong, Jeon, Byeong-Hwa“…E2-induced APE1/Ref-1secretion was remarkably suppressed by the estrogen receptor (ER) blocker fulvestrant and intracellular Ca(2+) chelator 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrakis (acetoxymethyl ester) (BAPTA-AM), suggesting E2-induced APE1/Ref-1 secretion was dependent on ER and intracellular calcium. …”
Publicado 2021
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14617por Liu, Yun, Hu, Ruixiang, Shen, Huanjia, Mo, Qinxin, Wang, Xinqiuyue, Zhang, Guiping, Li, Sujuan, Liang, Guanfeng, Hou, Ning, Luo, Jiandong“…Pretreatment with the IP(3)R inhibitor 2-Aminoethoxydiphenylborate (2-APB) attenuated intracellular Ca(2+) accumulation, and pretreatment with the Ca(2+) chelator 1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid (BAPTA) or the calcineurin inhibitor Cyclosporin A (CsA) inhibited EndoA2-knockdown-induced NRCM apoptosis. …”
Publicado 2021
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14618por Quigley, Neil Gerard, Steiger, Katja, Hoberück, Sebastian, Czech, Norbert, Zierke, Maximilian Alexander, Kossatz, Susanne, Pretze, Marc, Richter, Frauke, Weichert, Wilko, Pox, Christian, Kotzerke, Jörg, Notni, Johannes“…METHODS: Ga-68-Trivehexin was synthesized by trimerization of the optimized αvβ6-integrin selective cyclic nonapeptide Tyr2 (sequence: c[YRGDLAYp(NMe)K]) on the TRAP chelator core, followed by automated labeling with Ga-68. …”
Publicado 2021
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14619por Jayawardana, Sooriya Arachchige Sachini, Samarasekera, Jayanetti Koralalage Ramani Radhika, Hettiarachchi, Gardhi Hettiarachchige Chamari Madhu, Gooneratne, Jaanaki, Choudhary, Muhammad Iqbal, Jabeen, Almas“…Besides, they were able to reduce metal ions and chelate metal ions terminating radical generating reactions. …”
Publicado 2021
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14620“…Here we show that daytime BK current is resistant to the Ca(2+) chelator BAPTA. However, at night when LTCCs contribute little to BK activation, BK current decreases by a third in BAPTA compared to control EGTA conditions. …”
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