“…As regards the antioxidant assays, methanol stem bark extracts were characterized by the highest antioxidant activities (DPPH: 1.94 ± 0.01 mmol TE/g, ABTS: 3.31 ± 0.01 mmol TE/g, FRAP: 2.86 ± 0.02 mmol TE/g, CUPRAC: 5.09 ± 0.08 mmol TE/g, phosphomolybdenum: 5.16 ± 0.23 mmol TE/g and metal chelating: 17.12 ± 0.46 mg EDTAE/g). In addition, the methanolic extracts of stem bark had highest impact on acetylcholinesterase (2.54 mg GALAE/g), butyrylcholinesterase (5.48 mg GALAE/g). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The duck primary intestinal epithelial cells (DIECs) were divided into 6 groups: D-Zn (Zinc deficiency, treated with 2 µmol/L zinc Chelator TPEN), A-Zn (Adequate Zinc, basal medium), H-Zn (High level of Zn, supplemented with 20 µmol/L Zn), D-Zn + 20 µg/mL LPS, A-Zn + 20 µg/mL LPS, H-Zn + 20 µg/mL LPS. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Conclusion: NOTA-conjugated cyclic peptides derived from the known ACE2 inhibitor DX600 retain their activity when N-conjugated for (68)Ga chelation. In vivo studies in a transgenic hACE2 murine model using the lead tracer, (68)Ga-NOTA-PEP4, showed specific binding in the heart, liver, lungs and intestine—organs known to be affected in SARS-CoV-2 infection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This concept has been initially explored with analogs of the frog 14-peptide bombesin, suitably modified at the N-terminus with a number of radiometal chelates. Radiotracers that were selected for clinical testing revealed inherent problems associated with these GRPR agonists, related to low metabolic stability, unfavorable abdominal accumulation, and adverse effects. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The purified (165)Er was radiolabeled with standard radiometal chelators and used to produce and characterize a new AE-emitting radiopharmaceutical, [(165)Er]PSMA-617. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the presence of ethylene glycol tetra-acetic acid (a free Ca(2+) chelator, 1 mM) or U73122 (an inhibitor of phospholipase C, 1 μM), control and FGF-23-treated fibroblasts exhibited similar proliferative and migratory abilities. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The radiolabeling of (99m)Tc with two probes were via the conjugation of bifunctional chelator HYNIC. Then probes were purified by Sephadex G25 and tested for their radiolabeling efficiency and purity, as well as stability by ITLC (Instant thin-layer chromatography) and gel electrophoresis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Ultimately, the H(2)3,9-OPC2A shows advantageous features for further ligand designs for bifunctional chelators.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The aqueous extract of O. aquatica possessing the highest content of phenolics (60.85 mg gallic acid equivalent/g extract), also exhibited the strongest radical scavenging potential against 2,2-diphenyl-1-picrylhydrazyl and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (79.46 and 148.66 mg Trolox equivalent/g extract, respectively), the highest reducing ability (207.59 and 107.27 mg Trolox equivalent/g extract, for cupric reducing antioxidant capacity and ferric reducing antioxidant activity, respectively), metal chelating potential (33.91 mg ethylenediaminetetraacetic acid equivalent/g extract) and total antioxidant ability (1.60 mmol Trolox equivalent/g extract). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: To introduce imaging modalities, a peptide containing a near-infrared dye (sulfo-Cy5), a chelator (DTPA), an azide, and a sortase-recognition motif was synthesized. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Participants were randomly allocated into two groups (30 participants each group), received either 200 µg/day Se supplements (as Se amino acid chelate) or placebo from 16 to 18 weeks of pregnancy for 12 weeks. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We explored potential downstream mechanisms mediating this transporter-mediated dilation by using a Ca(2+) chelator or inhibitors of reversed-mode Na(+)/Ca(2+) exchange, nitric oxide synthetase, or cyclo-oxygenase. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: SiNP-Cu, a chelating matrix, was produced by delaying and slowing 1.5-dimethyl-1H-pyrazole-3-carbaldehyde on silica gel from functionalized with 3-aminopropyltrimethoxysilane. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Antioxidant capacities were assessed using DPPH, ABTS, FRAP, CUPRAC, phosphomolybdenum, metal chelating. The relationship between mode of extraction, plant parts and biological activities was determined using multivariate analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Because iron deposition is a major pathological event in ferroptosis, deferoxamine (DFO), an effective iron chelator, has been used to inhibit ferroptosis in various degenerative disease models. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Antioxidant activity was evaluated using the appropriate tests for: inhibition of lipid peroxidation, DPPH free radical scavenging assay, Fe(III)-reducing antioxidant power assay and ability of chelating Fe(2+) ions. The antibacterial activity against foodborne pathogens was measured by broth microdilution assay. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Methods: The synthesis of diethylenetriaminepentaacetic acid-bis-choline ethylamine [DTPA-bis(ChoEA)] featured the conjugation of dimethylaminoethanol to a bifunctional chelator DTPA anhydride. [(99m)Tc]Tc-DTPA-bis(ChoEA) was prepared, and its in vivo characteristics were evaluated in BALB/c mice and tumor-xenografted PC3, A549, and HCT116 athymic mouse models. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the case of the antioxidant potential, the ethyl acetate fraction (FXE) was demonstrated to have the most potent total antioxidant (26.3 ± 2.4 AAE μg mg(−1)), hydroxyl ion scavenging (IC(50) = 7.9 ± 0.9 μg mg(−1)), ferrous ion chelating (IC(50) = 28.2 ± 2.7 μg mg(−1)) and nitric oxide scavenging (IC(50) = 32.5 ± 2.9 μg mg(−1)) effects among all of the extract/fractions, whereas in the case of DPPH (IC(50) = 17.5 ± 2.7 μg mg(−1)) and the reducing power assay (16.7 ± 2.8 GAE μg mg(−1)), promising antioxidant potential was shown by the n-butanol fraction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The amine and anhydride groups may have a synergistic effect on Pb(2+) removal through electrostatic interactions and chelation; Fe(3)O(4)@SiO(2)@PEI-NTDA NPs exhibited preferable removal of Pb(2+) with maximum adsorption capacity of 285.3 mg g(−1) for Pb(2+) at a solution pH of 6.0, adsorbent dosage of 0.5 g L(−1), initial Pb(2+) concentration of 200 mg L(−1) and contact time of 3 h. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Pretreatment of cells with both PD98059 (an ERK1/2 inhibitor) and BAPTA/AM (a cell-permeable Ca(2+) chelator), but not SP600125 (a JNK inhibitor) and SB203580 (a p38 inhibitor), effectively suppressed NK-induced mitochondrial dysfunction, ER stress-related signals, and apoptotic events. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso