“…In view of this new evidence, mercury chelation therapy with intravenous calcium disodium ethylenediamine tetraacetic acid (CaNa(2)·EDTA) was initiated. …”
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“…Herein, Escherichia coli TG1 expressing hexahistidine-green fluorescent protein (His6GFP) and cells expressing polyhistidine-fused to the outer membrane protein A (His-OmpA) were applied as models to investigate roles of cytoplasmic metal complexation and metal chelation at the surface membrane, respectively, upon exposure to cadmium stress. …”
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“…This study was conducted to determine the effects of maternal dietary supplementation of ferrous glycine chelate (Fe-Gly) and ferrous sulfate monohydrate (FeSO(4)·H(2)O) on the relative organ weight, tissue iron contents, red blood cells (RBC), hemoglobin concentration (HGB) and hematocrit (HCT) in blood, as well as ferritin (Fn), serum iron (SI), and total iron binding capacity (TIBC) in serum of newborn piglets. …”
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“…After removal of the halogenides, the iridium center is stabilized by the carbonyl O atom through the formation of a five-membered chelate ring. A PCO pincer ligand system is thereby generated, which coordinates the iridium(III) atom threefold in a facial manner. …”
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“…The present study reports the novel green synthesis of stable ZnO NPs using various concentrations of zinc nitrate (0.01M, 0.05M, 0.1M) and Albizia lebbeck stem bark extracts as an efficient chelating agent. Antimicrobial, antioxidant, cytotoxic, and antiproliferative activities of the synthesized NPs on human breast cancer cell lines were evaluated using different assays. …”
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“…The endosialin-targeting scFv78-Fc fusion protein was conjugated with the chelator p-SCN-Bn-CHX-A”-DTPA, followed by labeling with either (152)Tb or (111)In. …”
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“…Finally, in vitro, sevelamer carbonate was capable of chelating a gut-derived uremic toxin IAA but not p-cresol and indole, the precursors of pCS and IS in the gut. …”
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“…A clinically approved SPIO for SLN localisation (Sienna+) was radiolabelled with (68)Ga without a chelator. Radiochemical stability was tested in human serum. …”
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“…In the cysteine and penicillamine complexes, double thiolate bridges join the Rh(III) ions, with the nonbridging Cys(2–) and Pen(2–) ligands in tridentate chelating (S,N,O) mode, which is consistent with the Δδ(C) = 7.3–8.4 ppm shift of the COO(–) signal in their carbon-13 cross polarization magic angle spinning (CPMAS) NMR spectra. …”
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“…The Zn(II) complexes poly[(4-chloro­pyridine-2,6-di­carboxyl­ato)zinc(II)], [Zn(C(7)H(2)ClNO(4))](n) or [Zn(Lig(2))](n), (3), and poly[[(4-hy­droxy­pyridine-2,6-di­carboxyl­ato)zinc(II)] monohydrate], {[Zn(C(7)H(3)NO(5))]·H(2)O}(n) or {[Zn(Lig(3))]·H(2)O}(n), (4), represent two-dimensional coordination polymers with chelating and bridging pyridine-2,6-di­carboxyl­ate ligands in which the coordination polyhedra about the central cations cannot be associated with any regular shape; their coordination environments range between trigonal–bipyramidal and square-pyramidal geometries. …”
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“…Furthermore, the molecule exhibits powerful reactive oxygen species (ROS) scavenging and metal-chelating properties. In this study, we assessed the efficiency of EPI to reverse ROS-mediated alterations to the motility, viability, DNA integrity and oxidative profile of bovine spermatozoa. …”
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“…Radiolabelling methods for complexing AE-emitters to biomolecules (antibodies and peptides) and nanoparticles include radioiodination ((125)I and (123)I) or radiometal chelation ((111)In, (67)Ga, (99m)Tc). Cancer cells exposed in vitro to AE-emitting radiotherapeutic agents exhibit decreased clonogenic survival correlated at least in part with unrepaired DNA double-strand breaks (DSBs) detected by immunofluorescence for γH2AX, and chromosomal aberrations. …”
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“…[Image: see text] Here we first report the design of a series of bis-chelate Co(II) 5,7-dihalo-8-quinolinol-phenanthroline derivative complexes, [Co(py)(QL1)(2)] (Co1), [Co(py)(QL2)(2)] (Co2), [Co(Phen)(QL1)(2)] (Co3), [Co(Phen)(QL2)(2)] (Co4), [Co(DPQ)(QL1)(2)]·(CH(3)OH)(4) (Co5), [Co(DPQ)(QL2)(2)] (Co6), [Co(DPPZ)(QL1)(2)]·CH(3)OH (Co7), [Co(MDP)(QL1)(2)]·3H(2)O (Co8), [Co(ODP)(QL1)(2)]·CH(3)OH (Co9), [Co(PPT)(QL1)(2)]·CH(3)OH (Co10), [Co(ClPT)(QL1)(2)] (Co11), [Co(dpy)(QL3)(2)] (Co12), [Co(mpy)(QL1)(2)] (Co13), [Co(Phen)(QL4)(2)] (Co14), [Co(ODP)(QL4)(2)] (Co15), [Co(mpy)(QL4)(2)]I (Co16), [Co(ClPT)(QL4)(2)] (Co17), and [Co(ClPT)(QL5)(2)] (Co18), with 5,7-dihalo-8-quinolinol and 2,2′-bipyridine mixed ligands. …”
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“…Treatment of cultured cells with the apoptosis inhibitor Z-Val-Ala-Asp (OMe)-fluoromethyl ketone (2–8 μM), autophagy inhibitor 3-methyladenine (100–400 μM) or necrosis inhibitor necrostatin-1 (10–40 μM) had no effect on glutamate induced cell damage. However, the iron chelator deferoxamine mesylate salt inhibited glutamate induced cell death. …”
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“…The ICP analysis of the effluent showed a total amount of chelated Si(+) ions of about 10.5 mg. In addition to the high temperature generated in the near-wellbore area, the pressure increased because of the produced nitrogen gas from the exothermic reaction and reached about 600 psi. …”
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“…In this study, two original urotensinergic analogues were first conjugated to a DOTA chelator via an aminohexanoic acid (Ahx) hydrocarbon linker and then -hUII and DOTA-urantide, complexed to the radioactive metal indium isotope to successfully lead to radiolabelled DOTA-Ahx-hUII and DOTA-Ahx-urantide. …”
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“…Factors were: 1) control or TM plus Met, which provided additional 10, 20, and 50 mg/kg of chelated copper, manganese, and zinc, respectively (0.1%, Aplomotec Plus, Tecnología & Vitaminas, S.L.; Alforja, Spain), and a 1.01 Met:Lys ratio and 2) standard Lys was formulated to meet growth requirements or low Lys to 19% below growth requirements. …”
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“…Survival and quality of life have improved progressively thanks to the implementation of a significant advance in diagnostic and therapeutic methods, consisting mainly of a frequent transfusion program combined with intensive chelation therapy. Improvement also includes imaging methods used to measure liver and cardiac iron overload. …”
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“…PROCEDURES: [(64)Cu]NOTA-CD8a was produced by enzymatic digestion of rat-anti-mouse CD8a antibody (clone YTS169.4), purified yielding isolated CD8a-F(ab)′2 fragments and randomly conjugated with the 2-S-(isothiocyanatbenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid (p-SCN-Bn-NOTA) chelator. NOTA-CD8a was radiolabeled with Cu-64 and injected into CT26 tumor-bearing mice for longitudinal assessment. …”
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“…As the toxic fraction of iron and its negative impact on MDS, iron overload monitoring and chelation treatment decision can also be supported by LCI.…”
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