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14821por Hajlaoui, Hafedh, Arraouadi, Soumaya, Noumi, Emira, Aouadi, Kaïss, Adnan, Mohd, Khan, Mushtaq Ahmad, Kadri, Adel, Snoussi, Mejdi“…Moreover, the mixture exhibited two-times greater ferric ion reducing antioxidant power (FRAP) (IC(50) = 11.33 ± 1.53 mg/mL) and equipotent chelating power (IC(50) = 31.33 ± 0.47 mg/mL) than the corresponding references, and also potent activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) (IC(50) = 19.00 ± 1.00 mg/mL), β-carotene (IC(50) = 11.16 ± 0.84 mg/mL), and superoxide anion (IC(50) = 10.33 ± 0.58 mg/mL) assays. …”
Publicado 2021
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14822por Yu, Lin-Na, Wang, Shi-Jin, Chen, Cheng, Rausch, Vanessa, Elshaarawy, Omar, Mueller, Sebastian“…Hepcidin blockage could be efficiently blunted by iron chelators salicylaldehyde isonicotinoyl hydrazone (SIH) and Desferal (P < 0.001). …”
Publicado 2021
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14823“…In addition, both the lipid reactive oxygen species (ROS) scavenger ferrostatin-1 and the iron chelator deferiprone attenuated ZnONPs-induced cell death. …”
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14824por Addison, Anthony W., Jaworski, Stephen J., Jasinski, Jerry P., Turnbull, Mark M., Xiao, Fan, Zeller, Matthias, O’Connor, Molly A., Brayman, Elizabeth A.“…Co(2)(Ppz)Cl(4) and {dichlorido{4-methyl-1-[2-(pyridin-2-yl)ethyl]-1,4-diazacycloheptane}cobalt(II) [CoCl(2)(C(13)H(21)N(3))] or Co(Pmhpz)Cl(2), crystallize in the monoclinic space group P2(1)/n, while crystals of the pentacoordinate monochloro chelate 1,4-bis[2-(pyridin-2-yl)ethyl]piperazine}chloridocobalt(II) perchlorate, [CoCl(C(18)H(24)N(4))]ClO(4) or [Co(Ppz)Cl]ClO(4), are also monoclinic (P2(1)). …”
Publicado 2022
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14825“…Its versatile chemistry includes not only coordination with classic N(∧)N neutral ligands but also the binding of negatively charged chelators, typically having a cyclometalating C(∧)N anchor. …”
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14826por Yoon, Ji Soo, Sasaki, Shugo, Velghe, Jane, Lee, Michelle Y. Y., Winata, Helena, Nian, Cuilan, Lynn, Francis C.“…METHODS: We exposed intact human islets from three donors to the following conditions: (1) 2.8 mmol/l glucose; (2) 16 mmol/l glucose and 40 mmol/l KCl to maximally stimulate Ca(2+) signalling; and (3) 16 mmol/l glucose, 40 mmol/l KCl and 5 mmol/l EGTA (Ca(2+) chelator) to inhibit Ca(2+) signalling, for 1 h. We sequenced 68,650 cells from all islet cell types, and further subsetted the cells to form an endocrine cell-specific dataset of 59,373 cells expressing INS, GCG, SST or PPY. …”
Publicado 2022
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14827“…The substitution reactivity increases from C(1) to C(3) owing to an increase in the π-conjugation on the bridging chelate which facilitates π-back bonding. As a result, the electrophilicity index on the C(3) complex increases than that on the complex C(2) followed by C(1) which leads to higher rates of substitution and thus the reactivity order follows C(1) < C(2) < C(3). …”
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14828por Schnipper, Julie, Kouba, Sana, Hague, Frédéric, Girault, Alban, Telliez, Marie-Sophie, Guénin, Stéphanie, Ahidouch, Ahmed, Pedersen, Stine Falsig, Ouadid-Ahidouch, Halima“…TRPC1 silencing decreases the basal Ca(2+) influx in acid-adapted and -recovered cells, but not in normal pH conditions, and Ca(2+) chelation reduces cell migration and proliferation solely in acid adaptation and recovery conditions. …”
Publicado 2022
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14829por Padakanti, Sowmya, Badhiwala, Vismay, Hwang, Munok, Choi, Hosoon, Chatterjee, Piyali, Dhar, Sorabh, Kaye, Keith S, Jinadatha, Chetan“…-sponsored study 212502|Merck: Advisor/Consultant|qpex: Advisor/Consultant|Shionogi: Grant/Research Support|Spero: Advisor/Consultant Chetan Jinadatha, MD, MPH, AHRQ R01 Grant-5R01HS025598: Grant/Research Support|EOS Surfaces: Copper Coupons and materials for testing.…”
Publicado 2022
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14830por Nelson, Richard, Ashby, Landon, Bennett, Morgan, Bridges, Angelia, Chatterjee, Piyali, Choi, Hosoon, Coppin, John David, Hwang, Munok, Navarathna, Thanuri, Williams, Marjory D, Xu, Jing, Jinadatha, Chetan“…DISCLOSURES: Piyali Chatterjee, PhD, AHRQ Grant # 1R03HS027667-01: Grant/Research Support|AHRQ Grant # 1R03HS027667-01: Central Texas Veterans Health Care System Chetan Jinadatha, MD, MPH, AHRQ R01 Grant-5R01HS025598: Grant/Research Support|EOS Surfaces: Copper Coupons and materials for testing.…”
Publicado 2022
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14831por Nolan, Terry, O’Ryan, Miguel, Santolaya, María Elena, De Looze, Ferdinandus, Marshall, Helen, Richmond, Peter, Henein, Sam, Rheault, Paul, Heaton, Ken, Perrett, Kirsten, Garfield, Hartley, Gupta, Anil, Ferguson, Murdo, D’Agostino, Diego, Toneatto, Daniela“…METHODS: This phase 3b, open-label, extension study (NCT02446743) assessed the antibody persistence and booster response at 4 years (Canada and Australia, NCT01423084) or 7.5 years (Chile, NCT00661713) after primary vaccination with 4CMenB (following 0 + 1-, 0 + 2-, or 0 + 6-month schedules), compared with vaccine-naïve (VN), healthy controls. Chilean follow-on (FO) and VN participants aged 18–24 years received either a booster dose of 4CMenB 7.5 years postprimary series (Group FO, N = 131) or 2 primary doses, 1 month apart (Group VN, N = 150). …”
Publicado 2018
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14832por Tapia, Alejandra, Barros, Eric, Vecchiola, Andrea, Campino, Carmen, Allende, Fidel, Baudrand, Rene, Salomon, Carlos, Fardella, Carlos, Carvajal, Cristian“…Mineralocorticoid arterial hypertension has risen as one of the most prevalent causes of secondary hypertension, where 11β-hydroxysteroid dehydrogenase type-2 partial deficiency (also known as non-classical AME (NC-AME)), could reach a prevalence of 7% in Chilean subjects. The phenotype of NC-AME is associated to high serum cortisol (F) to cortisone (E) ratio &low E, high potassium excretion and low-renin activity (Tapia-Castillo et al, JCEM 2018). …”
Publicado 2019
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14833por Menendez, Gonzalo Alfonso Dominguez, Mayorga, Helena Poggi, Moore, Rosario, D’Apremont, Ivonne, Arancibia, Monica, Bruce, Hernan Garcia, Kohen, Dafne Segall, Allende, Fidel, Solari, Sandra, Martinez, Alejandro“…UVB radiation measures obtained from the Chilean Meteorological Service’s database. Results: A total of one hundred thirty-three children were recruited (summer = 41, autumn = 28, winter = 35, spring = 29). …”
Publicado 2020
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14834por Savatt, Juliann M., Johns, Alicia, Schwartz, Marci L. B., McDonald, Whitney S., Salvati, Zachary M., Oritz, Nicole M., Masnick, Max, Hatchell, Kathryn, Hao, Jing, Buchanan, Adam H., Williams, Marc S.“…After result disclosure, among MyCode-identified participants, 99 (68.8%) had a recommended laboratory test and 36 (69.2%) with laboratory or liver biopsy evidence of iron overload began phlebotomy or chelation. Fifty-three (36.8%) had iron overload; rates of laboratory iron overload were higher in MyCode-identified participants than participants negative for p.Cys282Tyr homozygosity (females: 34.1% vs 2.1%, P < .001; males: 39.0% vs 2.9%, P < .001). …”
Publicado 2023
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14835por Yagi, Sakina, Uba, Abdullahi Ibrahim, Sinan, Kouadio Ibrahime, Piatti, Diletta, Sagratini, Gianni, Caprioli, Giovanni, Eltigani, Sayadat M., Lazarova, Irina, Zengin, Gökhan“…All extracts from RR had significant (p < 0.05) higher antioxidant activity than their respective WR except in their metal chelating power, where the methanolic extract of the latter showed the highest activity (3.87 mg EDTAE/g). …”
Publicado 2023
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14836“…Metallothioneins in general represent an impressive chelating agent for a wide range of metals. Structural studies carried out by a number of research groups (using (1)H and (113)Cd NMR, X-ray crystallography, more recently EXAFS, as well as optical spectroscopy) have established that there are three structural motifs for metal binding to mammalian metallothioneins. …”
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14837por Chan, Conrad, Scollard, Deborah A, McLarty, Kristin, Smith, Serena, Reilly, Raymond M“…This was due to higher levels of circulating radioactivity for (64)Cu-DOTA-trastuzumab Fab which disrupted the relationship between HER2 density and T/B ratios. Use of alternative chelators that more stably bind (64)Cu may improve the association between T/B ratios and HER2 density for (64)Cu-labeled trastuzumab Fab.…”
Publicado 2011
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14838por De Sanctis, Vincenzo, Elsedfy, Heba, Soliman, Ashraf T, Elhakim, Ihab Zaki, Pepe, Alessia, Kattamis, Christos, Soliman, Nada A., Elalaily, Rania, El Kholy, Mohamed, Yassin, Mohamed“…All patients were on regular transfusions and iron chelation therapy. Fasting venous blood samples were collected two weeks after transfusion to measure serum concentrations of IGF-1, free thyroxine (FT4), thyrotropin (TSH), cortisol, luteinizing hormone (LH), follicle stimulating hormone (FSH), total testosterone (TT), prolactin and estradiol (E2), glucose, urea, creatinine and electrolytes (including calcium and phosphate). …”
Publicado 2016
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14839por Pei, Lei, Wang, Zhenhua, Zhang, Jinzhu, Li, Wenhao, Ting, Adeline S. Y., Chow, Yiing Y., Rahman, Sadequr, Wei, Rongchang, Hu, Zhang, Li, Sidong, Li, Chuyan, Li, Zijuan, Wang, Guoxia, Yang, Yuzhen, Chen, Gang, Luo, Qing, Wang, Guoxia, Liu, Ruixia, Yang, Yuzhen, Chen, Lipei, Lie, Zhiyang, Zhou, Tongtong, Huang, Weilong, Xue, Li, Li, Jie, Wang, Zhuomin, Xue, Li, Bezirganoglu, Ismail, Uysal, Pınar, Wang, Shuihua, Lu, Zhihai, Yang, Jiquan, Zhang, Yudong, Liu, John, Wei, Ling, Chen, Shufang, Phillips, Preetha, Dong, Zhengchao, Li, Hong, Wang, Xutong, Zhao, Fengliang, Yang, Guisheng, Huang, Haijie, Zhao, Li, Huang, Weijian, Wang, Jinhui, Zhang, Zhongrun, Li, Xiaojuan, Xu, Ning, Zhou, Guofu, Wan, Ming, Lin, Qi, Meng, Fanyun, Li, Jianxiu, Chen, Yichang, Yu, Koayung, Chang, Chunpin, Zhou, Zijuan, Su, Peixi, Shi, Rui, Xie, Tingting, Shi, Rui, Su, Peixi, Zhou, Zijuan, Liu, Xuelan, Zhang, Yan, Wei, Xiangfa, Wu, Chong, Yin, Yanlei, Feng, Lijuan, Yang, Xuemei, Wang, Fei, Wang, Hua, Zhuang, Huifa, Zhu, Zihui, Wang, Hui“…Zhang Hu, Sidong Li, Chuyan Li, Zijuan Li 05 Two kinds of new characteristics of the ektexine ornamentation of ginkgo pollen Guoxia Wang, Yuzhen Yang, Gang Chen, Qing Luo 06 Analysis of nutrient and medicinal ingredients of Ginkgo pollen in different regions Guoxia Wang, Ruixia Liu, Yuzhen Yang, Lipei Chen 07 Photosynthetic performance of greening seedlings of seven species to drought stress Zhiyang Lie, Tongtong Zhou, Weilong Huang, Li Xue 08 Changes of fluorescence parameters of greening seedlings of seven species under drought stress Jie Li, Zhuomin Wang, Li Xue 09 Mammalian sex hormone affects regeneration capacity and enzymes activity of Triticale L in vitro culture Ismail Bezirganoglu, Pınar Uysal 10 Fractional Fourier entropy increases the recognition rate of fruit type detection Shuihua Wang, Zhihai Lu, Jiquan Yang, Yudong Zhang, John Liu, Ling Wei, Shufang Chen, Preetha Phillips, Zhengchao Dong 11 Banana-peanut intercropping reduces Fusarium wilt disease in banana from enhancing soil bacterial microorganisms and leaf nutrition Hong Li, Xutong Wang, Fengliang Zhao, Guisheng Yang 12 Manganese stress impairs stem ureide nitrogen fixation in yardlong-bean plants in the acidic environment Hong Li 13 A new pest control method for Rhytidodera bowringii Larvae Haijie Huang, Li Zhao, Weijian Huang, Jinhui Wang, Zhongrun Zhang 14 Research on the seed-like Fruits of Subg. …”
Publicado 2016
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14840por Strzeminska, Izabela, Factor, Cécile, Robert, Philippe, Grindel, Anne-Laure, Comby, Pierre-Olivier, Szpunar, Joanna, Corot, Claire, Lobinski, Ryszard“…Gadolinium speciation analysis of the water-soluble fraction showed that, after injection of the macrocyclic gadoterate, Gd was still detected only in its intact, chelated form 5 months after injection. In contrast, after a single dose of linear GBCAs (gadobenate and gadodiamide), 2 different forms were detected: intact GBCA and Gd bound to soluble macromolecules (above 80 kDa). …”
Publicado 2020
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