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  1. 1641
    “…Separate administration of an iron chelating agent has previously been demonstrated to significantly improve dermatological PpIX-PDT by further limiting heme production. …”
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    Experimental investigation of a combinational iron chelating protoporphyrin IX prodrug for fluorescence detection and photodynamic therapy
  2. 1642
    “…The use of aminopolycarboxylic acids (APCAs) is increasing rapidly in several industries because of their unique properties of chelation and their effectiveness in high-temperature conditions. …”
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    From initial treatment design to final disposal of chelating agents: a review of corrosion and degradation mechanisms
  3. 1643
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    A polycarboxylic chelating ligand for efficient resin purification of His-tagged proteins expressed in mammalian systems
  4. 1644
    “…The mechanism involves chelation processes, electrostatic interactions and mechanical trapping of the metal ions in the adsorbent pores. …”
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    New amino group functionalized porous carbon for strong chelation ability towards toxic heavy metals
  5. 1645
    “…A core–shell surface imprinted uranyl magnetic chelating adsorbent (UMCA) was synthesized by combining the sol–gel process with the surface molecular imprinting technique (SMIT). …”
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    A study on the preparation and application of a core–shell surface imprinted uranyl magnetic chelating adsorbent
  6. 1646
    “…However, it is largely unknown whether the copper chelator CPZ directly influences ion channels. Therefore, we assessed the effects of different divalent cations (copper; zinc) and trace metal chelators (EDTA; Tricine; the water-soluble derivative of CPZ, BiMPi) on hyperpolarization-activated cyclic nucleotide-gated (HCN) channels that are major mediators of thalamic function and pathology. …”
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    Effects of Axonal Demyelination, Inflammatory Cytokines and Divalent Cation Chelators on Thalamic HCN Channels and Oscillatory Bursting
  7. 1647
    “…Metal chelation is generally considered as a promising antifungal approach but its specific mechanisms are unclear. …”
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    Selective Metal Chelation by a Thiosemicarbazone Derivative Interferes with Mitochondrial Respiration and Ribosome Biogenesis in Candida albicans
  8. 1648
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    Nickel(0)-Catalyzed Decarbonylative Cross-Coupling of Aromatic Esters with Arylboronic Acids via Chelation Assistance
  9. 1649
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    Alpha radionuclide-chelated radioimmunotherapy promoters enable local radiotherapy/chemodynamic therapy to discourage cancer progression
  10. 1650
    “…Our group has designed novel iron chelator SK4 which targets cancer’s “iron addiction.” …”
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    Novel iron chelator SK4 demonstrates cytotoxicity in a range of tumour derived cell lines
  11. 1651
    “…Kinetic analyses of the formation rates of the cobalt(III)-hydroperoxido complexes reveal that second-order rate constants depend on the structural and electronic properties of the cobalt-supporting chelating ligands. An electron-withdrawing ligand opposite to the superoxide accelerates the hydrogen atom transfer (HAT) reaction from AZADOL due to an increase in the electrophilicity of the superoxide ligand. …”
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    The Conversion of Superoxide to Hydroperoxide on Cobalt(III) Depends on the Structural and Electronic Properties of Azole-Based Chelating Ligands
  12. 1652
    “…The use of degradable chelating agents to facilitate phytoextraction is a promising low-cost method for the remediation of heavy metal-contaminated soils. …”
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    Chemical forms of cadmium in soil and its distribution in French marigold sub-cells in response to chelator GLDA
  13. 1653
    por Ferrero, Maria Elena
    Publicado 2022
    “…Here, I provide an updated review on the damage to neurons promoted by toxic metals and on the impact of EDTA chelation therapy in ND patients, along with the clinical description of a representative case.…”
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    Neuron Protection by EDTA May Explain the Successful Outcomes of Toxic Metal Chelation Therapy in Neurodegenerative Diseases
  14. 1654
    por Kontoghiorghes, George J.
    Publicado 2022
    “…There is a need to readdress cancer therapy and include therapeutic strategies targeting multifactorial processes, including the application of multi-targeting drugs involving iron chelators and iron–chelator complexes. New therapeutic protocols including drug combinations with L1 and other chelating drugs could increase anticancer activity, decrease drug resistance and metastasis, improve treatments, reduce toxicity and increase overall survival in cancer patients.…”
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    New Iron Metabolic Pathways and Chelation Targeting Strategies Affecting the Treatment of All Types and Stages of Cancer
  15. 1655
    “…Based on the multitarget-directed ligands (MTDLs) strategy, a series of chromone-hydroxypyridinone hybrids were designed, synthesised, and evaluated as potential multimodal anti-AD ligands. Prospective iron-chelating effects and favourable monoamine oxidase B (MAO-B) inhibitory activities were observed for most of the compounds. …”
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    Chromone-based monoamine oxidase B inhibitor with potential iron-chelating activity for the treatment of Alzheimer’s disease
  16. 1656
    “…The development of (64)Cu-based immuno-PET radiotracers requires the use of copper-specific bifunctional chelators (BFCs) that contain functional groups allowing both convenient bioconjugation and stable copper complexes to limit in vivo bioreduction, transmetallation and/or transchelation. …”
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    Synthesis and In Vitro Comparison of DOTA, NODAGA and 15-5 Macrocycles as Chelators for the (64)Cu-Labelling of Immunoconjugates
  17. 1657
    “…The radionuclide (213)Bi(III) shows favourable physical properties for this application, but the fast and stable chelation of this metal ion remains challenging. Herein, we demonstrate that the mesocyclic chelator AAZTA quickly coordinates Bi(III) at room temperature, leading to a robust complex. …”
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    Boosting Bismuth(III) Complexation for Targeted α‐Therapy (TAT) Applications with the Mesocyclic Chelating Agent AAZTA
  18. 1658
    “…The mechanism by which Cd-exposed cells overcome calcium chelation and induce malignant transformation remains unclear. …”
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    Cadmium Activates EGFR/STAT5 Signaling to Overcome Calcium Chelation and Promote Epithelial to Mesenchymal Transition
  19. 1659
    “…SIMPLE SUMMARY: Excess iron is known to be a risk factor of carcinogenesis. Although iron chelators show anti-cancer effects, they have not been used successfully to treat cancer patients. …”
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    Highly Metastatic Subpopulation of TNBC Cells Has Limited Iron Metabolism and Is a Target of Iron Chelators
  20. 1660
    “…The chelate complex formation of Q1 with metal ions increased its penetration ability. …”
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    The Interaction of Anthracycline Based Quinone-Chelators with Model Lipid Membranes: (1)H NMR and MD Study
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