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  1. 1741
    por Kozol, Robert A., Dallman, Julia E.
    Publicado 2023
    “…Background: Altered sensory processing is a pervasive symptom in individuals with Autism Spectrum Disorders (ASD); people with Phelan McDermid syndrome (PMS), in particular, show reduced responses to sensory stimuli. …”
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    Drugs prescribed for Phelan-McDermid syndrome differentially impact sensory behaviors in shank3 zebrafish models.
  2. 1742
    “…For radiometal–antibody complexes, it is important to control the properties of the antibody–chelator conjugate to maintain the quality of the final product. …”
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    Process to Remove the Size Variants Contained in the Antibody–Chelator Complex PCTA-NCAB001 for Radiolabeling with Copper-64
  3. 1743
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    Effectiveness of a novel chelating agent in removing calcium hydroxide using conventional and passive ultrasonic irrigation techniques
  4. 1744
    “…Furthermore, potential problems associated with LSW such as scale precipitation in carbonate reservoirs and fine migration in sandstone reservoirs raise concerns. Chelating agents have the ability to chelate metal ions from solution, effectively reducing the salinity of seawater (SW) and mimicking the behavior of LSW. …”
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    A comprehensive evaluation of the effect of key parameters on the performance of DTPA chelating agent in modifying sandstone surface charge
  5. 1745
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    Crown-hydroxylamines are pH-dependent chelating N,O-ligands with a potential for aerobic oxidation catalysis
  6. 1746
    por Das, M., Livingstone, S. E.
    Publicado 1978
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    Metal chelates as anti-cancer agents. II cytotoxic action of palladium and platinum complexes of 6-mercaptopurine and thioguanine.
  7. 1747
    Publicado 1992
    “…Free Ca2+ is extruded, and probably also Ca2+ bound to CaM or other chelators, while CaM and the chelators are retained in the cell.…”
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    Calmodulin activation of the Ca2+ pump revealed by fluorescent chelator dyes in human red blood cell ghosts
  8. 1748
    “…OBJECTIVE: Many patients with transfusional iron overload are at risk for progressive organ dysfunction and early death and poor compliance with older chelation therapies is believed to be a major contributing factor. …”
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    Efficacy and safety of deferasirox, an oral iron chelator, in heavily iron-overloaded patients with β-thalassaemia: the ESCALATOR study
  9. 1749
    “…CONCLUSION: This case supports the use of chelation therapy with disodium edetate to remove damages caused by mercury intoxication.…”
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    The usefulness of chelation therapy for the remission of symptoms caused by previous treatment with mercury-containing pharmaceuticals: a case report
  10. 1750
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    pH-Potentiometric Investigation towards Chelating Tendencies of p-Hydroquinone and Phenol Iminodiacetate Copper(II) Complexes
  11. 1751
    “…The title compound, C(27)H(47)NO(3), is a (3-hydroxy­prop­yl)amide derivative of naturally occurring enanti­opure lithocholic acid (3α-hydr­oxy-5β-cholan-24-oic acid). The mol­ecule contains four fused rings: three six-membered rings in chair conformations and one five-membered ring in a half-chair form. …”
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    3α-Hydr­oxy-N-(3-hydroxy­prop­yl)-5β-cholan-24-amide
  12. 1752
    “…BACKGROUND: The 70% methanol extract of Terminalia chebula Retz. fruit (TCME) was investigated for its in vitro iron chelating property and in vivo ameliorating effect on hepatic injury of iron overloaded mice. …”
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    Reducing power and iron chelating property of Terminalia chebula (Retz.) alleviates iron induced liver toxicity in mice
  13. 1753
    “…(V.) braziliensis was analyzed by the use of the chelator 2,2-dipyridyl. Treatment with 2,2-dipyridyl affected parasites' growth in a dose- and time-dependent manner. …”
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    Cellular Growth and Mitochondrial Ultrastructure of Leishmania (Viannia) braziliensis Promastigotes Are Affected by the Iron Chelator 2,2-Dipyridyl
  14. 1754
    “…The goal of this research was to evaluate some morphological and physiological responses of morning glory grown on a Pb- and chelate-amended soil. Soil samples were analyzed, at Mississippi State University Soil Laboratory, for physico-chemical parameters, such as soil texture (73% sand, 23% silt, 4.4% clay), organic matter (6.24 ± 0.60%), and pH (7.95 ± 0.03), to establish soil conditions at the beginning of the experiments. …”
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    Morphological and Physiological Responses of Morning Glory (Ipomoea lacunosa L.) Grown in a Lead- and Chelate-Amended Soil
  15. 1755
    “…These differences could largely be reversed by the iron chelator desferal and to some degree by the iron chelator clioquinol, or by the free radical trapping agents salicylate or selenite (that may themselves also be iron chelators). …”
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    Profound Morphological Changes in the Erythrocytes and Fibrin Networks of Patients with Hemochromatosis or with Hyperferritinemia, and Their Normalization by Iron Chelators and Other Agents
  16. 1756
    “…MT2A overexpression induced chemoresistance to cytotoxic drugs through direct chelation of platinum-containing drugs and indirect action on p53 zinc-dependent activity. …”
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    Zinc chelation: a metallothionein 2A's mechanism of action involved in osteosarcoma cell death and chemotherapy resistance
  17. 1757
    “…By this, we find, compared to regular docking, QM based chelation calculations to significantly reduce the large number of false positives. …”
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    Inhibitor Ranking through QM Based Chelation Calculations for Virtual Screening of HIV-1 RNase H Inhibition
  18. 1758
    “…Herein, we present an octadentate chelator 3,4,3-(LI-1,2-HOPO) (or HOPO) as a potentially superior alternative to DFO. …”
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    Alternative Chelator for (89)Zr Radiopharmaceuticals: Radiolabeling and Evaluation of 3,4,3-(LI-1,2-HOPO)
  19. 1759
    “…We have previously shown that ATN-224, a copper chelator drug, induces cell death in murine thymic lymphoma cells transfected with Bcl-2. …”
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    The copper chelator ATN-224 induces caspase-independent cell death in diffuse large B cell lymphoma
  20. 1760
    “…Here we study the anti-tumor activity of the metal chelator, TPEN, and define its mechanism of action. …”
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    Copper chelation selectively kills colon cancer cells through redox cycling and generation of reactive oxygen species
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