A Single and Two-Stage, Closed-Tube, Molecular Test for the 2019 Novel Coronavirus (COVID-19) at Home, Clinic, and Points of Entry

por El-Tholoth, Mohamed, Bau, Haim H., Song, Jinzhao
Publicado 2020

Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019-nCoV

por Morse, Jared S., Lalonde, Tyler, Xu, Shiqing, Liu, Wenshe R.
Publicado 2020

Shotgun drug repurposing biotechnology to tackle epidemics and pandemics

por Mangione, William, Falls, Zackary, Melendy, Thomas, Chopra, Gaurav, Samudrala, Ram
Publicado 2020

Computational models identify several FDA approved or experimental drugs as putative agents against SARS-CoV-2

por Bobrowski, Tesia, Alves, Vinicius M., Melo-Filho, Cleber C., Korn, Daniel, Auerbach, Scott, Schmitt, Charles, Muratov, Eugene N., Tropsha, Alexander
Publicado 2020

Homology modeling of TMPRSS2 yields candidate drugs that may inhibit entry of SARS-CoV-2 into human cells.

por Rensi, Stefano, Keys, Allison, Lo, Yu-Chen, Derry, Alexander, McInnes, Greg, Liu, Tianyun, Altman, Russ
Publicado 2020

Fast Identification of Possible Drug Treatment of Coronavirus Disease −19 (COVID-19) Through Computational Drug Repurposing Study

por Wang, Junmei
Publicado 2020

An online repository of solvation thermodynamic and structural maps of SARS-CoV-2 targets

por Olson, Brian, Cruz, Anthony, Chen, Lieyang, Ghattas, Mossa, Ji, Yeonji, Huang, Kunhui, McKay, Daniel J, Kurtzman, Tom
Publicado 2020

Computational target-based drug repurposing of elbasvir, an antiviral drug predicted to bind multiple SARS-CoV-2 proteins

por Balasubramaniam, Meenakshisundaram, Reis, Robert J. Shmookler
Publicado 2020

Structural Similarity of SARS-CoV2 M(pro) and HCV NS3/4A Proteases Suggests New Approaches for Identifying Existing Drugs Useful as COVID-19 Therapeutics

por Bafna, Khushboo, Krug, Robert M., Montelione, Gaetano T.
Publicado 2020

COVID-KOP: Integrating Emerging COVID-19 Data with the ROBOKOP Database

por Korn, Daniel, Bobrowski, Tesia, Li, Michael, Kebede, Yaphet, Wang, Patrick, Owen, Phillips, Vaidya, Gaurav, Muratov, Eugene, Chirkova, Rada, Bizon, Chris, Tropsha, Alexander
Publicado 2020

A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19

por Zhou, Yadi, Hou, Yuan, Shen, Jiayu, Kallianpur, Asha, Zein, Joe, Culver, Daniel A., Farha, Samar, Comhair, Suzy, Fiocchi, Claudio, Gack, Michaela U., Mehra, Reena, Stappenbeck, Thaddeus, Chan, Timothy, Eng, Charis, Jung, Jae U., Jehi, Lara, Erzurum, Serpil, Cheng, Feixiong
Publicado 2020

Adaptive evolution of peptide inhibitors for mutating SARS-CoV-2

por Chaturvedi, Parth, Han, Yanxiao, Král, Petr, Vuković, Lela
Publicado 2020

A rational design of a multi-epitope vaccine against SARS-CoV-2 which accounts for the glycan shield of the spike glycoprotein

por Martin, William R., Cheng, Feixiong
Publicado 2020

Structure-Based Drug Design of an Inhibitor of the SARS-CoV-2 (COVID-19) Main Protease Using Free Software: A Tutorial for Students and Scientists

por Zhang, Sheng, Krumberger, Maj, Morris, Michael A., Parrocha, Chelsea Marie T., Griffin, James H., Kreutzer, Adam G., Nowick, James S.
Publicado 2020

LCMS Measurement of Steroid Biomarkers Collected from Palmar Sweat.

por Runyon, J. Ray, Hyde, Jacob N., Staroschak, Christina, Kromenacker, Bryan, Wilson, Robert C., Sternberg, Esther M.
Publicado 2020

Tuning proton transfer thermodynamics in SARS-Cov-2 main protease: implications for catalysis and inhibitor design

por Zanetti-Polzi, Laura, Smith, Micholas Dean, Chipot, Chris, Gumbart, James C., Lynch, Diane L., Pavlova, Anna, Smith, Jeremy C., Daidone, Isabella
Publicado 2020

A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening

por Gorgulla, Christoph, Padmanabha Das, Krishna M., Leigh, Kendra E., Cespugli, Marco, Fischer, Patrick D., Wang, Zi-Fu, Tesseyre, Guilhem, Pandita, Shreya, Shnapir, Alec, Calderaio, Anthony, Gechev, Minko, Rose, Alexander, Lewis, Noam, Hutcheson, Colin, Yaffe, Erez, Luxenburg, Roni, Herce, Henry D., Durmaz, Vedat, Halazonetis, Thanos D., Fackeldey, Konstantin, Patten, Justin J., Chuprina, Alexander, Dziuba, Igor, Plekhova, Alla, Moroz, Yurii, Radchenko, Dmytro, Tarkhanova, Olga, Yavnyuk, Irina, Gruber, Christian, Yust, Ryan, Payne, Dave, Näär, Anders M., Namchuk, Mark N., Davey, Robert A., Wagner, Gerhard, Kinney, Jamie, Arthanari, Haribabu
Publicado 2020

Supercomputer-Based Ensemble Docking Drug Discovery Pipeline with Application to Covid-19

por Acharya, A., Agarwal, R., Baker, M., Baudry, J., Bhowmik, D., Boehm, S., Byler, K. G., Coates, L., Chen, S.Y., Cooper, C.J., Demerdash, O., Daidone, I., Eblen, J.D., Ellingson, S., Forli, S., Glaser, J., Gumbart, J. C., Gunnels, J., Hernandez, O., Irle, S., Larkin, J., Lawrence, T.J., LeGrand, S., Liu, S.-H., Mitchell, J.C., Park, G., Parks, J.M., Pavlova, A., Petridis, L., Poole, D., Pouchard, L., Ramanathan, A., Rogers, D., Santos-Martins, D., Scheinberg, A., Sedova, A., Shen, S., Smith, J.C., Smith, M.D., Soto, C., Tsaris, A., Thavappiragasam, M., Tillack, A.F., Vermaas, J.V., Vuong, V.Q., Yin, J., Yoo, S., Zahran, M., Zanetti-Polzi, L.
Publicado 2020

Copper(II) Inhibition of the SARS-CoV-2 Main Protease

por Garza-López, Roberto A., Kozak, John J., Gray, Harry B.
Publicado 2020

REDIAL-2020: A suite of machine learning models to estimate Anti-SARS-CoV-2 activities

por Govinda, KC, Bocci, Giovanni, Verma, Srijan, Hassan, Mahmudulla, Holmes, Jayme, Yang, Jeremy J., Sirimulla, Suman, Oprea, Tudor I.
Publicado 2020