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881por Huber, Julia M., Amann, Arno, Koeck, Stefan, Lorenz, Edith, Kelm, Jens M., Obexer, Petra, Zwierzina, Heinz, Gamerith, Gabriele“…METHODS: The non-small cell lung cancer (NSCLC) cell line Colo699 was cultivated as monolayer (2D) on plates for 5 days or as microtissues (3D) using a hanging-drop system for 5 and 10 days. …”
Publicado 2016
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882por Henderson, Sally E., Ding, Li-Yun, Mo, Xiaokui, Bekaii-Saab, Tanios, Kulp, Samuel K., Chen, Ching-Shih, Huang, Po-Hsien“…EXPERIMENTAL DESIGN: The in vitro antiproliferative activity of AR-42 was evaluated in six human pancreatic cancer cell lines (AsPC-1, COLO-357, PANC-1, MiaPaCa-2, BxPC-3, SW1990). AsPC-1 subcutaneous xenograft and transgenic KP(fl/fl)C (LSL-Kras(G12D);Trp53(flox/flox);Pdx-1-Cre) mouse models of pancreatic cancer were used to evaluate the in vivo efficacy of AR-42 in suppressing tumor growth and/or muscle wasting. …”
Publicado 2016
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883por Tamhankar, Anup Sunil, Ingle, Parag, Engineer, Reena, Bal, Munita, Ostwal, Vikas, Saklani, Avanish“…METHODS: It’s a retrospective study (2011-2014) of all patients diagnosed with signet ring colo-rectal cancer (SRCC). Various clinico-pathological variables were studied. …”
Publicado 2016
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884“…Further, we have used human colon cancer cell lines, HT29 and COLO205, and mouse primary embryonic fibroblast to understand the molecular mechanism of WDR13 action. …”
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885“…Colo-Rectal Cancer is a common cancer worldwide with 5–10% cases being hereditary. …”
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886por Kovacs, Eva“…In this study, the effects of VAQuFrF extract were compared with those of vincristine in six human multiple myeloma cell lines (Molp-8, LP-1, RPMI-8226, OPM-2, Colo-677, and KMS-12-BM) using an in vitro model. …”
Publicado 2010
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887por Patra, Arup Ranjan, Roy, Somnath Singha, Basu, Abhishek, Bhuniya, Avishek, Bhattacharjee, Arin, Hajra, Subhadip, Sk, Ugir Hossain, Baral, Rathindranath, Bhattacharya, Sudin“…Additionally, MUS synergistically enhanced the cytotoxicity of carboplatin against two human cancer cell lines (MCF-7 and Colo-205). Furthermore, MUS can effectively potentiate the antitumour activity of carboplatin against two murine cancers (Dalton’s Lymphoma and Sarcoma-180) in vivo. …”
Publicado 2018
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888por Fernández, Lara P., Ramos-Ruiz, Ricardo, Herranz, Jesús, Martín-Hernández, Roberto, Vargas, Teodoro, Mendiola, Marta, Guerra, Laura, Reglero, Guillermo, Feliu, Jaime, Ramírez de Molina, Ana“…The overexpression of four lipid metabolism-related genes (ABCA1, ACSL1, AGPAT1 and SCD genes) has been proposed as prognostic marker of stage II CRC (ColoLipidGene signature). In order to explore in depth the transcriptomic and genomic scenarios of ABCA1, ACSL1, AGPAT1 and SCD genes, we performed a transcriptomic meta-analysis in more than one thousand CRC individuals. …”
Publicado 2017
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889por Throm, Verena M., Männle, David, Giese, Thomas, Bauer, Andrea S., Gaida, Matthias M., Kopitz, Juergen, Bruckner, Thomas, Plaschke, Konstanze, Grekova, Svetlana P., Felix, Klaus, Hackert, Thilo, Giese, Nathalia A., Strobel, Oliver“…The CHRNA7 mRNA levels were decreased in PDAC, and CHRNA7(high)-PDAC patients lived longer. In CHRNA7(high) COLO357 and PANC-1 cultures, opposing activities of SLURP1 (anti-malignant/CHRNA7-dependent) and nicotine (pro-malignant/CHRNA7-infidel) were exerted without reciprocally interfering with receptor binding or downstream signaling. …”
Publicado 2018
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890“…Operative time for loop colostomy closure was shorter than with divided colo6stomy (76 minutes vs 94 minutes, P=.002). Three patients among the divided group had reversed orientation of the colostomy that had affected bowel preparations negatively prior to its repair. …”
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891“…Repression of LGR5 by DDX1 knockdown was observed in 2 other human colorectal cancer cell lines, Colo320 and SW837. These results suggest that LGR5 is a critical effector of DDX1 in colorectal cancer cells. …”
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892por Halekotte, Jakob, Witt, Lydia, Ianes, Chiara, Krüger, Marc, Bührmann, Mike, Rauh, Daniel, Pichlo, Christian, Brunstein, Elena, Luxenburger, Andreas, Baumann, Ulrich, Knippschild, Uwe, Bischof, Joachim, Peifer, Christian“…Cellular efficacy has been evaluated in human pancreatic cancer cell lines Colo357 (EC(50) = 3.5 µM) and Panc89 (EC(50) = 1.5 µM). …”
Publicado 2017
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893por Radke, David I., Ling, Qi, Häsler, Robert, Alp, Gökhan, Ungefroren, Hendrik, Trauzold, Anna“…Moreover, stable TRAIL-R1 knockdown in Colo357 cells increased TGFβ1-induced SERPINE1 expression and this effect was partially reversed by transient expression of the miR-370 mimic. …”
Publicado 2018
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894por Jang, Jee-Eun, Kim, Hwang-Phill, Han, Sae-Won, Jang, Hoon, Lee, Si-Hyun, Song, Sang-Hyun, Bang, Duhee, Kim, Tae-You“…Knockdown of NFATC3–PLA2G15 using siRNA reduced mRNA expression of epithelial–mesenchymal transition (EMT) markers such as vimentin, twist, and fibronectin and increased mesenchymal–epithelial transition markers of E-cadherin, claudin-1, and FOXC2 in colo-320 cell line harboring NFATC3–PLA2G15 FT. The NFATC3–PLA2G15 knockdown also inhibited invasion, colony formation capacity, and cell proliferation. …”
Publicado 2019
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895National cohort study on postoperative risks after surgery for submucosal invasive colorectal cancerpor Vermeer, N. C. A., Backes, Y., Snijders, H. S., Bastiaannet, E., Liefers, G. J., Moons, L. M. G., van de Velde, C. J. H., Peeters, K. C. M. J.“…METHODS: This was a population‐based cohort study of patients treated surgically for pT1–3 colorectal cancer between 2009 and 2016, using data from the Dutch ColoRectal Audit. Postoperative complications (overall, surgical, severe complications and mortality) were compared using multivariable logistic regression. …”
Publicado 2018
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896por López-Gil Otero, María del Mar, Romero-Ventosa, Elena Yaiza, Feijoo-Meléndez, Débora, Casanova-Martínez, Cristina, Otero-Millán, Luis, Piñeiro-Corrales, Guadalupe“…CONCLUSIONS: The treatment with nebulised colistin during 6 and 12 months of non-cystic fibrosis bronchiectasis, colo-nised/infected by P. aeruginosa, seems beneficial for the pa-tient, from the clinical and quality of life point of view, and could reduce the economic cost of the process.…”
Publicado 2019
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897por Geijsen, Anne J.M.R., Brezina, Stefanie, Keski‐Rahkonen, Pekka, Baierl, Andreas, Bachleitner‐Hofmann, Thomas, Bergmann, Michael M., Boehm, Juergen, Brenner, Hermann, Chang‐Claude, Jenny, van Duijnhoven, Fränzel J.B., Gigic, Biljana, Gumpenberger, Tanja, Hofer, Philipp, Hoffmeister, Michael, Holowatyj, Andreana N., Karner‐Hanusch, Judith, Kok, Dieuwertje E., Leeb, Gernot, Ulvik, Arve, Robinot, Nivonirina, Ose, Jennifer, Stift, Anton, Schrotz‐King, Petra, Ulrich, Alexis B., Ueland, Per Magne, Kampman, Ellen, Scalbert, Augustin, Habermann, Nina, Gsur, Andrea, Ulrich, Cornelia M.“…Here, we performed a ultrahigh performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (UHPLC‐QTOF‐MS) screening on EDTA plasma from 268 colorectal cancer patients and 353 controls using independent discovery and replication sets from two European cohorts (ColoCare Study: n = 180 patients/n = 153 controls; the Colorectal Cancer Study of Austria (CORSA) n = 88 patients/n = 200 controls), aiming to identify circulating plasma metabolites associated with colorectal cancer and to improve knowledge regarding colorectal cancer etiology. …”
Publicado 2019
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898por Swaminathan, Srividya, Haribabu, Jebiti, Kalagatur, Naveen Kumar, Konakanchi, Ramaiah, Balakrishnan, Nithya, Bhuvanesh, Nattamai, Karvembu, Ramasamy“…The cytotoxicity of the complexes was evaluated against four different cancer cell lines: MCF-7 (breast), COLO 205 (colon), A549 (lung), and IMR-32 (neuroblastoma). …”
Publicado 2019
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899por Xie, Ming, Liang, Jin-Long, Huang, Han-Dong, Wang, Mai-Jian, Zhang, Tao, Yang, Xue-Feng“…MATERIALS AND METHODS: Colon cancer cell lines COLO 205 and SW480 were employed in our study. The cells were treated with NP or E2 followed by measurement of apoptosis and proliferation using flow cytometry and MTT assays, respectively. …”
Publicado 2019
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900por Hope, Jacob M., Lopez-Cavestany, Maria, Wang, Wenjun, Reinhart-King, Cynthia A., King, Michael R.“…A significant increase in apoptosis occurred when PC3, COLO 205, or MDA-MB-231 cells were treated with Yoda1 and TRAIL in combination, but not in Bax-deficient DU145 cells. …”
Publicado 2019
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