Mostrando 21 - 40 Resultados de 191 Para Buscar 'Cushing (Maine)', tiempo de consulta: 0.60s Limitar resultados
  1. 21
    “…Cushing’s syndrome (CS) is a rare condition associated with increased morbidity and mortality. …”
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    “…BACKGROUND: Glucocorticoid excess in Cushing disease (CD) leads to negative feedback suppression, resulting in Crooke's hyaline change (CC) of nontumorous pituitary corticotrophs. …”
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  5. 25
    por Fasen, Madeline, Mayson, Sarah Emily
    Publicado 2023
    “…Conclusion: The severity of hypercortisolism is a negative predictor of survival and prompt control should be the main therapeutic goal along with prevention of cortisol-induced complications in patients with ECS. …”
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  6. 26
    “…Drug therapies are indicated for patients without initial remission or with surgical contraindications or recurrence, and ketoconazole is one of the main available therapies. The objective of this study was to evaluate the safety profile of and the treatment response to ketoconazole in Cushing’s disease patients followed up at the endocrinology outpatient clinic of a Brazilian university hospital. …”
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  7. 27
    “…Introduction: Patients with Cushing’s syndrome (CS) present a higher mortality compared with the general population mainly due to cardiovascular and infectious diseases. …”
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    “…F.Z. Alharraki: None. Cushing syndrome is one of the endocrine diseases that is mainly due to the high levels of cortisol. …”
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    “…This perioperative endocrine therapy for patients with Cushing's syndrome (mainly for adrenocortical adenoma) undergoing retro-laparoscopic adrenalectomy is both effective and safe.…”
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  11. 31
    “…OBJECTIVE: To investigate the validity of discharge ICD-10 codes in detecting the etiology of endogenous Cushing’s syndrome (CS) in hospitalized patients. METHODS: We evaluated the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of CS etiology-related ICD-10 codes or code combinations by comparing hospital discharge administrative data (DAD) with established diagnoses from medical records. …”
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    “…SUMMARY: Osilodrostat is a novel, orally administered cortisol synthesis inhibitor, approved in 2020 by the European Medicines Agency (EMA) for the treatment of Cushing’s syndrome in adults. A significant amount of the studies currently available in the literature focus on treatment in patients with Cushing’s disease. …”
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    “…CONTEXT: Elevated human choriogonadotropin (hCG) may stimulate aberrantly expressed luteinizing hormone (LH)/hCG receptor (LHCGR) in adrenal glands, resulting in pregnancy-induced bilateral macronodular adrenal hyperplasia and transient Cushing syndrome (CS). OBJECTIVE: To determine the role of LHCGR in transient, pregnancy-induced CS. …”
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    “…It usually metastasizes to distant organs at time of diagnosis and rarely presents as Cushing syndrome. Surgical resection is the main management of localized tumors with controlling the effects of secreted hormones. …”
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    “…BACKGROUND Cushing's disease (CD) is mainly due to pituitary microadenomas producing ACTH. …”
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  19. 39
    “…OBJECTIVES: establish the relationship between Cushing’s syndrome and bipolar disorder and identify the main pillars of care. …”
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    “…However, in vivo studies demonstrated normalization of urinary cortisol (UC) in about 30-40% of cases over the long term, mainly after surgical failure. Objective: To evaluate the effect of CAB as monotherapy in early preoperative period and on recurrence of Cushing’s disease. …”
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