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21“…Cushing’s syndrome (CS) is a rare condition associated with increased morbidity and mortality. …”
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22Choroidal and Retinal Abnormalities by Optical Coherence Tomography in Endogenous Cushing’s Syndromepor Abalem, Maria Fernanda, Machado, Marcio Carlos, Santos, Helen Nazareth Veloso Dos, Garcia, Rafael, Helal, John, Carricondo, Pedro Carlos, Pimentel, Sérgio Luis Gianotti, Monteiro, Mario Luiz Ribeiro, Qian, Cynthia X., Bronstein, Marcello Delano, Fragoso, Maria Cândida Villares Barisson“…METHODS: Choroidal and retinal morphology was assessed using OCT. MAIN OUTCOME MEASURES: Choroidal thickness measurements and the presence of retinal changes. …”
Publicado 2016
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23Clinical characterization of patients with primary aldosteronism plus subclinical Cushing’s syndromepor Yasuda, Shigemitsu, Hikima, Yusuke, Kabeya, Yusuke, Iida, Shinichiro, Oikawa, Yoichi, Isshiki, Masashi, Inoue, Ikuo, Shimada, Akira, Noda, Mitsuhiko“…BACKGROUND: Primary aldosteronism (PA) plus subclinical Cushing’s syndrome (SCS), PASCS, has occasionally been reported. …”
Publicado 2020
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24por Akirov, Amit, Larouche, Vincent, Shimon, Ilan, Asa, Sylvia L., Mete, Ozgur, Sawka, Anna M., Gentili, Fred, Ezzat, Shereen“…BACKGROUND: Glucocorticoid excess in Cushing disease (CD) leads to negative feedback suppression, resulting in Crooke's hyaline change (CC) of nontumorous pituitary corticotrophs. …”
Publicado 2021
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25“…Conclusion: The severity of hypercortisolism is a negative predictor of survival and prompt control should be the main therapeutic goal along with prevention of cortisol-induced complications in patients with ECS. …”
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26por Viecceli, Camila, Mattos, Ana Carolina Viana, Costa, Maria Carolina Bittencourt, de Melo, Rafael Borba, Rodrigues, Ticiana da Costa, Czepielewski, Mauro Antonio“…Drug therapies are indicated for patients without initial remission or with surgical contraindications or recurrence, and ketoconazole is one of the main available therapies. The objective of this study was to evaluate the safety profile of and the treatment response to ketoconazole in Cushing’s disease patients followed up at the endocrinology outpatient clinic of a Brazilian university hospital. …”
Publicado 2022
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27por Valente do Couto, Hugo, Sampaio, Klevia, Peres, Bruna, de Castro Musolino, Nina, Cescato, Valter, Silva, Gilberto, Fragoso, Maria, Bronstein, Marcello, Machado, Marcio“…Introduction: Patients with Cushing’s syndrome (CS) present a higher mortality compared with the general population mainly due to cardiovascular and infectious diseases. …”
Publicado 2019
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28“…F.Z. Alharraki: None. Cushing syndrome is one of the endocrine diseases that is mainly due to the high levels of cortisol. …”
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29por Brzezniak, Christina E., Vietor, Nicole, Hogan, Patricia E., Oronsky, Bryan, Thilagar, Bennett, Ray, Carolyn M., Caroen, Scott, Lybeck, Michelle, Oronsky, Neil, Carter, Corey A.“…Carcinoid tumors are neuroendocrine tumors that mainly arise in the gastrointestinal tract, lungs, and bronchi. …”
Publicado 2017
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30por Cui, Xiaobo, Yang, Lu, Li, Jianwei, Bu, Siyuan, Wei, Qiang, An, Zhenmei, Fan, Tianyong“…This perioperative endocrine therapy for patients with Cushing's syndrome (mainly for adrenocortical adenoma) undergoing retro-laparoscopic adrenalectomy is both effective and safe.…”
Publicado 2012
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31por Zhou, Jingya, Zhang, Meng, Lu, Lin, Guo, Xiaopeng, Gao, Lu, Yan, Weigang, Pang, Haiyu, Wang, Yi, Xing, Bing“…OBJECTIVE: To investigate the validity of discharge ICD-10 codes in detecting the etiology of endogenous Cushing’s syndrome (CS) in hospitalized patients. METHODS: We evaluated the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of CS etiology-related ICD-10 codes or code combinations by comparing hospital discharge administrative data (DAD) with established diagnoses from medical records. …”
Publicado 2019
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32por Caffarini, Miriam, Armeni, Tatiana, Pellegrino, Pamela, Cianfruglia, Laura, Martino, Marianna, Offidani, Annamaria, Di Benedetto, Giovanni, Arnaldi, Giorgio, Campanati, Anna, Orciani, Monia“…Cushing syndrome (CS), caused by glucocorticoid (GCs) excess, is strictly connected to onset of different metabolic diseases and impaired wound healing. …”
Publicado 2019
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33por Antonini, Simone, Brunetti, Alessandro, Zampetti, Benedetta, Boeris, Davide, Saladino, Andrea, Cesare Cozzi, Renato“…SUMMARY: Osilodrostat is a novel, orally administered cortisol synthesis inhibitor, approved in 2020 by the European Medicines Agency (EMA) for the treatment of Cushing’s syndrome in adults. A significant amount of the studies currently available in the literature focus on treatment in patients with Cushing’s disease. …”
Publicado 2022
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34por Plöckinger, Ursula, Chrusciel, Marcin, Doroszko, Milena, Saeger, Wolfgang, Blankenstein, Oliver, Weizsäcker, Katharina, Kroiss, Matthias, Hauptmann, Kathrin, Radke, Cornelia, Pöllinger, Alexander, Tiling, Nikolaus, Steinmüller, Thomas, Huhtaniemi, Ilpo, Quinkler, Marcus, Bertherat, Jerome, Lacroix, André, Rahman, Nafis“…CONTEXT: Elevated human choriogonadotropin (hCG) may stimulate aberrantly expressed luteinizing hormone (LH)/hCG receptor (LHCGR) in adrenal glands, resulting in pregnancy-induced bilateral macronodular adrenal hyperplasia and transient Cushing syndrome (CS). OBJECTIVE: To determine the role of LHCGR in transient, pregnancy-induced CS. …”
Publicado 2017
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35por Seastedt, Kenneth P., Alyateem, George A., Pittala, Karthik, Steinberg, Seth M., Schrump, David S., Nieman, Lynnette K., Hoang, Chuong D.“…IMPORTANCE: Ectopic adrenocorticotropic hormone secretion from lung tumors causing Cushing syndrome are associated with high rates of morbidity. …”
Publicado 2021
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36por Soares, Vinicius, Martins, Clarissa, Martinez, Edson, Domingues de Araújo, Leonardo, Roa, Silvia, Silva, Lucas, Moreira, Ayrton, De Castro, Margaret“…Main Outcome Measures: Participants underwent salivary cortisol measurement at 0900h and 2300h. …”
Publicado 2019
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37“…It usually metastasizes to distant organs at time of diagnosis and rarely presents as Cushing syndrome. Surgical resection is the main management of localized tumors with controlling the effects of secreted hormones. …”
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38“…BACKGROUND Cushing's disease (CD) is mainly due to pituitary microadenomas producing ACTH. …”
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39“…OBJECTIVES: establish the relationship between Cushing’s syndrome and bipolar disorder and identify the main pillars of care. …”
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40por Pereira, Ana Julia Garcia, Andrade, Natália Xavier S, Musolino, Nina Rosa de Castro, Cescato, Valter Angelo Sperling, da Silva, Gilberto Ochman, Fragoso, Maria Candida Barisson Villares, Bronstein, Marcello Delano, Machado, Marcio Carlos“…However, in vivo studies demonstrated normalization of urinary cortisol (UC) in about 30-40% of cases over the long term, mainly after surgical failure. Objective: To evaluate the effect of CAB as monotherapy in early preoperative period and on recurrence of Cushing’s disease. …”
Publicado 2020
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