Mostrando 61 - 80 Resultados de 191 Para Buscar 'Cushing (Maine)', tiempo de consulta: 0.17s Limitar resultados
  1. 61
    “…Associations between GR polymorphisms and multiple vascular, body composition and metabolic parameters were investigated. MAIN OUTCOME MEASURES: Allelic frequencies of the polymorphisms and their associations with several cardiometabolic risk factors. …”
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  2. 62
    “…CONCLUSION: While well-described in older children and adults, in neonates the Cushing reflex has mainly been described in animal experiments and infants who have developed hydrocephalus. …”
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  3. 63
    “…Background: Autonomous glucocorticoid excess in patients with Cushing disease (CD) may lead to negative feedback suppression, resulting in Crooke's hyaline change (CC) of the non-tumorous corticotrophs in the pituitary. …”
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  4. 64
    “…CONTEXT: Impaired cognition and altered quality of life (QoL) may persist despite long-term remission of Cushing’s disease (CD). Persistent comorbidities and treatment modalities may account for cognitive impairments. …”
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  5. 65
    “…CONTEXT: Confirming a diagnosis of Cushing disease (CD) remains challenging, yet is critically important before recommending transsphenoidal surgery for adenoma resection. …”
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  6. 66
    por Firme, Ricardo
    Publicado 2019
    “…Salivary cortisol increased in comparison to baseline in patients with Cushing’s disease (range: 66 to 309%) mainly at 60 minutes, declining thereafter. …”
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  7. 67
    “…BACKGROUND: Cushing’s syndrome (CS) is a rare clinical condition caused by excessive cortisol secretion from adrenal glands. …”
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  8. 68
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  10. 70
    “…CONTEXT: Late-night salivary cortisol (LNSC) measured by enzyme immunoassay (EIA-F) is a first-line screening test for Cushing syndrome (CS) with a reported sensitivity and specificity of >90%. …”
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  11. 71
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  13. 73
    “…In these cases, when considering ACTH-independent hypercortisolism, the main etiology reported is adrenal adenoma. We will describe the case of an acromegalic patient with ACTH-independent cushing syndrome due to adrenal cortical carcinoma. …”
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  14. 74
  15. 75
    por Kim, Kyungwon
    Publicado 2023
    “…Serum ACTH level determines the successful lateralization of ACTH secreting pituitary tumor in Cushing disease. Presentation: Thursday, June 15, 2023…”
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  16. 76
    “…PURPOSE: In a 10-week proof-of-concept study (LINC 1), the potent oral 11β-hydroxylase inhibitor osilodrostat (LCI699) normalized urinary free cortisol (UFC) in 11/12 patients with Cushing’s disease. The current 22-week study (LINC 2; NCT01331239) further evaluated osilodrostat in patients with Cushing’s disease. …”
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  17. 77
    “…BACKGROUND: Increased urinary free cortisol in response to the oral administration of dexamethasone is a paradoxical reaction mainly reported in patients with primary pigmented nodular adrenocortical disease. …”
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  18. 78
    “…BACKGROUND: Although surgery is considered the first-line treatment for patients with endogenous Cushing’s syndrome (CS), medical therapy is often required to control severe hypercortisolism. …”
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  19. 79
    “…Clinical cases: Herein, we present two unrelated patients with ACTH-independent CS that harbor USP8 gene variants. USP8 is mainly known for being mutated in Cushing disease but as a deubiquitinase it may be involved into the Wnt/β-Catenin signaling pathway. …”
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  20. 80
    “…Cushing´s syndrome (CS) secondary to bilateral adrenal cortical disease may be caused by bilateral macronodular adrenal cortical disease (BMACD) or by bilateral micronodular adrenal cortical disease (miBACD). …”
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