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202261por Pacheco, Ana, Soós, Balázs, Lempel, Edina, Simon, Imre, Maróti, Péter, Möhlhenrich, Stephan Christian, Szalma, József“…CLINICAL RELEVANCE: Coronectomy sections may result in lingual hard and soft tissue injury with the possibility of damaging the lingual nerve. The precision of the buccolingual depth-control can be improved, while surgical time can be reduced when applying a drilling sleeve. …”
Publicado 2023
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202262por Sun, G., Zang, Y., Ding, H., Chen, Y., Groothof, D., Gong, H., Lou, Z., Meng, R., Chen, Z., Furnee, E., Xiang, J., Zhang, W.“…Compared to intersphincteric resection (ISR), CSPO retains more dentate line and distal rectal wall, and also avoids damaging the nerves in the intersphincteric space. …”
Publicado 2023
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202263por Pratesi, G, Perego, P, Polizzi, D, Righetti, S C, Supino, R, Caserini, C, Manzotti, C, Giuliani, F C, Pezzoni, G, Tognella, S, Spinelli, S, Farrell, N, Zunino, F“…The peculiar pattern of anti-tumour activity of the triplatinum complex and its ability to induce p53-independent cell death may have relevant pharmacological implications, since p53, a critical protein involved in DNA repair and induction of apoptosis by conventional DNA-damaging agents, is defective in several human tumours. …”
Publicado 1999
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202264por Morguette, Ana Elisa Belotto, Bigotto, Briani Gisele, Varella, Renata de Lima, Andriani, Gabriella Maria, Spoladori, Laís Fernanda de Almeida, Pereira, Patrícia Moraes Lopes, de Andrade, Fabio Goulart, Lancheros, Cesar Armando Contreras, Nakamura, Celso Vataru, Syogo Arakawa, Nilton, Bruschi, Marcos Luciano, Carlos Tomaz, José, Lonni, Audrey Alesandra Stinghen Garcia, Kerbauy, Gilselena, Tavares, Eliandro Reis, Yamauchi, Lucy Megumi, Yamada-Ogatta, Sueli Fumie“…Microscopy analyses of planktonic GBS cells treated with copaiba oil revealed morphological and ultrastructural alterations, displaying disruption of the cell wall, damaged cell membrane, decreased electron density of the cytoplasm, presence of intracellular condensed material, and asymmetric septa. …”
Publicado 2019
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202265“…BACKGROUND: Victimisation of women is encountered in all countries across the world, it damages the mental and physical health of women. During pregnancy and the postpartum period, women are at a greater risk of experiencing violence from an intimate partner. …”
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202266por Di Benedetto, Paola, Guggino, Giuliana, Manzi, Giovanna, Ruscitti, Piero, Berardicurti, Onorina, Panzera, Noemi, Grazia, Nicolò, Badagliacca, Roberto, Riccieri, Valeria, Vizza, Carmine Dario, Radchenko, Ganna, Liakouli, Vasiliki, Ciccia, Francesco, Cipriani, Paola, Giacomelli, Roberto“…Interleukin-32 (IL-32) is a proinflammatory cytokine expressed in damaged vascular cells, and the present study aimed to assess if this cytokine could be a new biomarker of PAH during SSc. …”
Publicado 2020
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202267por Naher, Nahitun, Hoque, Roksana, Hassan, Muhammad Shaikh, Balabanova, Dina, Adams, Alayne M., Ahmed, Syed Masud“…Poor salary and benefits, poor incentives and motivation, and poor governance have a damaging impact on health outcomes and the quality of health care services. …”
Publicado 2020
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202268por Smith, Brandon C., Sinyuk, Maksim, Jenkins, Julius E., Psenicka, Morgan W., Williams, Jessica L.“…In vitro, IFNγ stimulation enhanced iP expression, reduced reactive oxygen species burden, and decreased oxidatively damaged and poly-ubiquitinated protein accumulation preferentially in human spinal cord astrocytes, which was abrogated with the use of the iP inhibitor, ONX 0914. …”
Publicado 2020
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202269“…These molecular and pathological changes suggested increased inflammation in damaged kidneys. Oxidative stress, as evidenced by an increased level of MDA and decreased levels of SOD1 and Catalase, was also observed in UUO kidneys. …”
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202270por Labadie, Julia D., Elvers, Ingegerd, Feigelson, Heather Spencer, Magzamen, Sheryl, Yoshimoto, Janna, Dossey, Jeremy, Burnett, Robert, Avery, Anne C.“…Targeted resequencing of this region using a custom sequence capture array identified missense mutations in all three genes; the variant in SPAM1 was predicted to be damaging. These mutations were also associated with risk for mast cell tumors among Golden Retrievers in an unrelated study. …”
Publicado 2020
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202271por Briet, Olivier, Koenker, Hannah, Norris, Laura, Wiegand, Ryan, Vanden Eng, Jodi, Thackeray, Alex, Williamson, John, Gimnig, John E., Fortes, Filomeno, Akogbeto, Martin, Yadouleton, Anges W., Ombok, Maurice, Bayoh, M. Nabie, Mzilahowa, Themba, Abílio, Ana Paula, Mabunda, Samuel, Cuamba, Nelson, Diouf, Elhadji, Konaté, Lassana, Hamainza, Busiku, Katebe-Sakala, Cecilia, Ponce de León, Gabriel, Asamoa, Kwame, Wolkon, Adam, Smith, Stephen C., Swamidoss, Isabel, Green, Mike, Gueye, Salam, Mihigo, Jules, Morgan, Juliette, Dotson, Ellen, Craig, Allen S., Tan, Kathrine R., Wirtz, Robert A., Smith, Tom“…While LLINs are expected to last at least 3 years under normal use conditions, they can lose effectiveness because they fall out of use, are discarded, repurposed, physically damaged, or lose insecticidal activity. The contributions of these different interrelated factors to durability of nets and their protection against malaria have been unclear. …”
Publicado 2020
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202272por Gheller, Brandon J., Blum, Jamie E., Fong, Ern Hwei Hannah, Malysheva, Olga V., Cosgrove, Benjamin D., Thalacker-Mercer, Anna E.“…To ensure efficient skeletal muscle regeneration after injury, MuSCs must undergo state transitions as they are activated from quiescence, give rise to a population of proliferating myoblasts, and continue either to terminal differentiation, to repair or replace damaged myofibers, or self-renewal to repopulate the quiescent population. …”
Publicado 2020
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202273por França, Elisabeth, Ishitani, Lenice Harumi, Teixeira, Renato, Duncan, Bruce B., Marinho, Fatima, Naghavi, Mohsen“…GC levels 1 and 2 are the most damaging unusable codes, or major GCs. Proportionate distribution of deaths by GC levels according selected variables were performed. …”
Publicado 2020
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202274“…Among them, 26.8% (1,904,787 cases) were attributed to vascular complications in damaged organs, including the kidneys (1,355,085 cases, 71.1%), peripheral circulatory (515,293 cases, 27.1%), nerves (28,697 cases, 1.5%) and eyes (5751 cases, 0.3%). …”
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202275por Alexeev, Vitali, Olavarria, Jacquelyn, Bonaldo, Paolo, Merlini, Luciano, Igoucheva, Olga“…Also, the specific populations of ADSC selected with an affinity for the chemokines being released by damaged muscle showed efficient migration to injured site and presented their therapeutic effect. …”
Publicado 2020
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202276por Safa, Farhana, Anjum, Afifa, Hossain, Sahadat, Trisa, Tonima Islam, Alam, Syeda Fatema, Abdur Rafi, Md., Podder, Vivek, Koly, Kamrun Nahar, Azad, Dewan Tasnia, Ahmad, Wasi Uddin, Nodi, Rhedeya Nury, Ashraf, Fatema, Quamrul Akhter, S.M., Ahmed, Helal Uddin, Hasan, M. Tasdik“…BACKGROUND: The most recent global pandemic of COVID-19 has been creating multidimensional damages, including a detrimental impact on the mental health status of individuals. …”
Publicado 2021
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202277por Wu, Lei, Quan, Wen, Yue, Guojun, Luo, Qiong, Peng, Dongxu, Pan, Ying, Zhang, Guihai“…BACKGROUND: Autophagy is a highly conserved homeostatic process in the human body that is responsible for the elimination of aggregated proteins and damaged organelles. Several autophagy-related genes (ARGs) contribute to the process of tumorigenesis and metastasis of prostate cancer (PCa). …”
Publicado 2021
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202278por Son, Seung Seob, Hwang, Soohyun, Park, Jun Hong, Ko, Youngho, Yun, Sung-Il, Lee, Ji-Hye, Son, Beomseok, Kim, Tae Rim, Park, Han-Oh, Lee, Eun Young“…In both kidney disease models, SAMiRNA-AREG was delivered primarily to the damaged kidney. We also confirmed the protective effect of SAMiRNA-AREG in renal fibrosis models. …”
Publicado 2021
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202279por Li, Guangdi, Zhang, Mi, Huang, Yuan, Yang, Jiafei, Dong, Lianghong, Shi, Hao, Li, Long, Liu, Riguang, Li, Jiangwei“…Normal cell counts were significantly reduced, cartilage extracellular matrix was obviously damaged, and type II collagen expression was significantly decreased. …”
Publicado 2021
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202280por Lin, Li-Yun, Huang, Hui-Ying, Liang, Xue-Yan, Xie, Dong-De, Chen, Jiang-Tao, Wei, Hua-Gui, Huang, Wei-Yi, Ehapo, Carlos Salas, Eyi, Urbano Monsuy, Li, Jian, Wang, Jun-Li, Zheng, Yu-Zhong, Zha, Guang-Cai, Wang, Yu-Ling, Chen, Wei-Zhong, Liu, Xiang-Zhi, Mo, Huan-Tong, Chen, Xin-Yao, Lin, Min“…The mutations I116T, L221I, Y128F, G228V and P299S were predicted as probably damaging by PolyPhen online service, while mutations L49V, R285G, R285S, P299S and K421N would lead to a significant increase of free energy difference (ΔΔG > 1) indicated a destabilization of protein structure. …”
Publicado 2021
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