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202701por Sharma, Niharika, Radha, Kumar, Manoj, Kumari, Neeraj, Puri, Sunil, Rais, Nadeem, Natta, Suman, Dhumal, Sangram, Navamaniraj, Nelson, Chandran, Deepak, Mohankumar, Pran, Muthukumar, Muthamilselvan, Senapathy, Marisennayya, Deshmukh, Vishal, Damale, Rahul D., Anitha, T., Balamurugan, V., Sathish, G., Lorenzo, Jose M.Enlace del recurso
Publicado 2023
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202702por Pultz, Christina Juul, Lohse, Thea Mundt, Justesen, Just Bendix, Særvoll, Charlotte Ahlgren, Møller, Sofie Fønsskov, Lindegaard, Birgitte, Fischer, Thea K., Dalager, Tina, Molsted, StigEnlace del recurso
Publicado 2023
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202703por Rennie, Sarah, Dalby, Maria, Lloret-Llinares, Marta, Bakoulis, Stylianos, Dalager Vaagensø, Christian, Heick Jensen, Torben, Andersson, RobinEnlace del recurso
Publicado 2018
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202704por Nimbalkar, Urja D., Seijas, Julio A., Vazquez-Tato, Maria Pilar, Damale, Manoj G., Sangshetti, Jaiprakash N., Nikalje, Anna Pratima G.Enlace del recurso
Publicado 2017
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202705por Nielsen, Hans Linde, Tarpgaard, Irene Harder, Fuglsang-Damgaard, David, Thomsen, Philip Kjettinge, Brisse, Sylvain, Dalager-Pedersen, MichaelEnlace del recurso
Publicado 2018
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202706“…Based on this background, milled wood lignins (MWL(ML) and MWL(FZ)) and lignin-carbohydrate complexes (LCC(ML) and LCC(FZ)) were isolated from the shells of Ginkgo biloba L. cv. Damaling (ML) and Ginkgo biloba L. cv. Dafozhi (FZ) correspondingly, and were structurally characterized by comprehensive NMR spectroscopy. …”
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202707“…In this work, a new methodology that uses faults emulation to obtain parameters similar to the Development and Application of Methods for Diagnosis of Actuators in Industrial Control Systems (DAMADICS) benchmark model will be developed. This methodology uses previous information from tests on sensors with and without faults to detect and classify the situation of the plant and, in the presence of faults, perform the diagnosis through a process of elimination in a hierarchical manner. …”
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202708por Kumar, Manoj, Radha, Devi, Himani, Prakash, Suraj, Rathore, Sonia, Thakur, Mamta, Puri, Sunil, Pundir, Ashok, Bangar, Sneh Punia, Changan, Sushil, Ilakiya, Tamilselvan, Samota, Mahesh Kumar, Damale, Rahul D., Singh, Surinder, Berwal, Mukesh K., Dhumal, Sangram, Bhoite, Anilkumar G., Sharma, Anshu, Senapathy, Marisennayya, Bhushan, Bharat, Maurya, Vineet Kumar, Asha, Natta, Suman, Amarowicz, Ryszard, Mekhemar, MohamedEnlace del recurso
Publicado 2021
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202709por Altantogtokh, Doniddemberel, Lilak, Abigail A., Takhampunya, Ratree, Sakolvaree, Jira, Chanarat, Nitima, Matulis, Graham, Poole-Smith, Betty Katherine, Boldbaatar, Bazartseren, Davidson, Silas, Hertz, Jeffrey, Bolorchimeg, Buyandelger, Tsogbadrakh, Nyamdorj, Fiorenzano, Jodi M., Lindroth, Erica J., von Fricken, Michael E.“…This study sought to further characterize tick-borne pathogens present in Dermacentor ticks (n = 1,773) sampled in 2019 from 15 of Mongolia’s 21 aimags (provinces). The ticks were morphologically identified and sorted into 377 pools which were then screened using Next-Generation Sequencing paired with confirmatory PCR and DNA sequence analysis. …”
Publicado 2022
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202710por Pan, Li, E, Tianjiao, Xu, Chengyu, Fan, Xiapu, Xia, Jiajia, Liu, Yan, Liu, Jiawei, Zhao, Jinpeng, Bao, Nan, Zhao, Yuan, Sun, Hui, Qin, Guixin, Farouk, Mohammed Hamdy“…SBA up-regulated mitochondrial fission variant protein (FIS1) and fusion protein (Mfn2) promoted CytC and AIF in mitochondria to enter the cytoplasm, activated caspase-9 and caspase-3, damaged or declined mitochondrial function and reduced ATP synthesis (p < 0.05). …”
Publicado 2023
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202711por Xu, Wenchang, Liu, Xinqi, Han, Wenjuan, Wu, Keling, Zhao, Minglei, Mei, Tingfang, Shang, Bizhi, Wu, Jinwen, Luo, Jingyi, Lai, Yuhua, Yang, Boyu, Zhuo, Yehong, Lu, Lin, Liu, Yizhi, Tian, Xiao-li, Zhao, Ling“…CONCLUSIONS: Our study showed elevated HTRA1 contributes to the pathogenesis of AMD by promoting cellular senescence in RPE through damaging mitochondrial function and activating HIF-1 signaling. …”
Publicado 2023
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202712por Lee, Jihoon, Sung, Ki Woon, Bae, Eun-Jin, Yoon, Dabin, Kim, Dasarang, Lee, Jin Saem, Park, Da-ha, Park, Daniel Youngjae, Mun, Su Ran, Kwon, Soon Chul, Kim, Hye Yeon, Min, Joo-Ok, Lee, Seung-Jae, Suh, Young Ho, Kwon, Yong Tae“…In PD cellular models, ATC161 exhibited therapeutic efficacy to reduce cell-to-cell transmission of α-syn and to rescue cells from the damages in DNA and mitochondria. In PD mice established by injecting α-syn preformed fibrils (PFFs) into brain striata via stereotaxic surgery, oral administration of ATC161 at 10 mg/kg induced the degradation of α-syn aggregates and reduced their propagation. …”
Publicado 2023
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202713por Osuna-Caballero, Salvador, Olivoto, Tiago, Jiménez-Vaquero, Manuel A., Rubiales, Diego, Rispail, Nicolas“…BACKGROUND: Rust is a damaging disease affecting vital crops, including pea, and identifying highly resistant genotypes remains a challenge. …”
Publicado 2023
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202714por Jiang, Huijiao, Wang, Xiaoyi, Guo, Lijiao, Tan, Xiaowu, Gui, Xianwei, Liao, Zhenyu, Li, Zhiwei, Chen, Xueling, Wu, Xiangwei“…Host-targeted anti-angiogenesis treatment strategies constitute a new avenue for the treatment of AE. GRAPHICAL ABSTRACT: [Image: see text]…”
Publicado 2023
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202715por Gratten, Jacob, Zhao, Qiongyi, Benyamin, Beben, Garton, Fleur, He, Ji, Leo, Paul J., Mangelsdorf, Marie, Anderson, Lisa, Zhang, Zong-Hong, Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Edson, Janette, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jin, Zi-Bing, Li, Zhongshan, Lin, Yong, Liu, Xiaolu, Marshall, Mhairi, Mowry, Bryan J., Ran, Shu, Reutens, David C., Song, Sharon, Tan, Li-Jun, Tang, Lu, Wallace, Robyn H., Wheeler, Lawrie, Wu, Jinyu, Yang, Jian, Xu, Huji, Visscher, Peter M., Bartlett, Perry F., Brown, Matthew A., Wray, Naomi R., Fan, Dongsheng“…We assessed evidence for an excess of rare damaging mutations at the gene level and the gene set level, considering only singleton variants filtered to have allele frequency less than 5 × 10(–5) in reference databases. …”
Publicado 2017
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202716por Jäger, Ralf, Mohr, Alex E., Carpenter, Katie C., Kerksick, Chad M., Purpura, Martin, Moussa, Adel, Townsend, Jeremy R., Lamprecht, Manfred, West, Nicholas P., Black, Katherine, Gleeson, Michael, Pyne, David B., Wells, Shawn D., Arent, Shawn M., Smith-Ryan, Abbie E., Kreider, Richard B., Campbell, Bill I., Bannock, Laurent, Scheiman, Jonathan, Wissent, Craig J., Pane, Marco, Kalman, Douglas S., Pugh, Jamie N., ter Haar, Jessica A., Antonio, Jose“…Administration of selected anti-inflammatory probiotic strains have been linked to improved recovery from muscle-damaging exercise. 9. The minimal effective dose and method of administration (potency per serving, single vs. split dose, delivery form) of a specific probiotic strain depends on validation studies for this particular strain. …”
Publicado 2019
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202717por Ma, Shixing, Zhang, Aobo, Li, Xiaole, Zhang, Shizhou, Liu, Shaopeng, Zhao, Haoming, Wu, Shichao, Chen, Lei, Ma, Chuan, Zhao, Huaqiang“…RESULTS: In the UAC model, the cartilage thickness and extracellular matrix of miR-21-5p knockout mice were less damaged, and miR-21-5p and UAC model were shown to affect the expression of Spry1, IL-1β, MMP-13, and VEGF. …”
Publicado 2020
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202718por Harder, Jeffrey M., Williams, Pete A., Braine, Catherine E., Yang, Hongtian S., Thomas, Jocelyn M., Foxworth, Nicole E., John, Simon W. M., Howell, Gareth R.“…CONCLUSIONS: C3AR1 was identified as a damaging neuroinflammatory factor. These data help suggest complement activation causes glaucomatous neurodegeneration through multiple mechanisms, including inflammation. …”
Publicado 2020
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202719por Zhang, Xin, Li, Yuting, Sun, Yulong, Guo, Mingxing, Feng, Jianjun, Wang, Yilei, Zhang, Ziping“…As molecular chaperones, heat shock proteins (HSPs) are a group of highly conserved proteins that help in the refolding of misfolded proteins and the elimination of irreversibly damaged proteins. They are mediated by a family of transcription factors called heat shock factors (HSFs). …”
Publicado 2020
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202720por Sprave, Tanja, Zöller, Daniela, Stoian, Raluca, Rühle, Alexander, Kalckreuth, Tobias, Haehl, Erik, Fahrner, Harald, Binder, Harald, Grosu, Anca-Ligia, Heinemann, Felix, Nicolay, Nils Henrik“…Patients with HNC have a high burden of symptoms due to both the damaging effects of the tumor and the aggressive multimodal treatment. …”
Publicado 2020
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